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Gastric cancer (GC) is one of the leading causes of cancer-related deaths worldwide. Despite progress in the last decades, there are still no reliable biomarkers for the diagnosis of and prognosis for GC.
Michael W.L. Quirino +7 more
doaj +1 more source
FUCA2 and TSTA3 expression in gastric cancer: candidate biomarkers of malignant transformation
INTRODUCTION: Aberrant fucosylation is closely related to malignant transformation, cancer detection, and evaluation of treatment efficacy. The fucosylation process requires GDP-L-fucose, fucosyltransferases, and fucosidases.
Michael Williames Leal Quirino +7 more
doaj +1 more source
Development, Characterization, and Immunomodulatory Evaluation of Carvacrol-loaded Nanoemulsion
Carvacrol (CV) is an essential oil with numerous therapeutic properties, including immunomodulatory activity. However, this effect has not been studied in nanoemulsion systems.
Amanda Gabrielle Barros Dantas +6 more
doaj +1 more source
Synthetic thiophenes induce chromosomal damage and trigger apoptosis in human cancer cell lines
Thiophenes are heterocyclic compounds containing a five-membered ring with sulphur as the heteroatom. This class of substances has been shown to have several biological activities, including specific anti-proliferative effects against some cancer cell ...
Filipe N. Franco +10 more
doaj +1 more source
Excessive daytime sleepiness in adolescents: current treatment strategies [PDF]
The complaints of excessive daytime sleepiness are very common among adolescents. In addition, in this particular subpopulation, the presence of excessive daytime sleepiness is associated with negative impact on school ...
Matthieu Hein +3 more
doaj +1 more source
Galectins as pivotal components in oncogenesis and immune exclusion in human malignancies
Galectins are galactoside-binding proteins, exerting numerous functions inside and outside the cell, particularly conferring adaptation to stress factors. For most of them, aberrant expression profiles have been reported in the context of cancer.
Nikiforos-Ioannis Kapetanakis +1 more
doaj +1 more source
Inclusion body myositis: therapeutic approaches. [PDF]
The idiopathic inflammatory myopathies are a heterogeneous group of diseases that include dermatomyositis (DM), polymyositis (PM), inclusion body myositis (IBM) and other less common myopathies.
Aggarwal, Rohit, Oddis, Chester V
core +1 more source
Measuring quality in the therapeutic relationship-Part 2: subjective approaches [PDF]
Publisher version: http://qualitysafety.bmj.com/content/19/6/479 ...
Greenhalgh, T, Heath, I
core +1 more source
Syncope: therapeutic approaches.
Syncope is a common clinical problem characterized by transient, spontaneously self-terminating loss of consciousness with complete and prompt recovery; the cause is insufficiency of cerebral oxygen/nutrient supply most often due to a transient fall of systemic arterial pressure to levels below those tolerated by cerebrovascular autoregulation. Careful
Benditt, David G., Nguyen, John T.
openaire +2 more sources
In silico and in vitro drug screening identifies new therapeutic approaches for Ewing sarcoma. [PDF]
The long-term overall survival of Ewing sarcoma (EWS) patients remains poor; less than 30% of patients with metastatic or recurrent disease survive despite aggressive combinations of chemotherapy, radiation and surgery.
Alturkmani, Hani +11 more
core +8 more sources

