Antibiotic resistance in K. pneumoniae: perspectives, challenges, health risks, therapeutic approaches [PDF]
Frontiers in MicrobiologyKlebsiella pneumoniae is an opportunistic Gram-negative pathogen of increasing global concern due to its expanding virulence potential and rapid acquisition of antimicrobial resistance.
Tülay Kandemir +6 more
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Advances in Therapeutic Approaches to Gastric Cancer. [PDF]
Ca-A Cancer Journal for CliniciansJiafu Ji, Rui-Hua Xu, Jia-Fu Ji
exaly +2 more sources
European Journal of Histochemistry, 2022 Gastric cancer (GC) is one of the leading causes of cancer-related deaths worldwide. Despite progress in the last decades, there are still no reliable biomarkers for the diagnosis of and prognosis for GC.
Michael W.L. Quirino +7 more
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FUCA2 and TSTA3 expression in gastric cancer: candidate biomarkers of malignant transformation
Folia Histochemica et Cytobiologica, 2022 INTRODUCTION: Aberrant fucosylation is closely related to malignant transformation, cancer detection, and evaluation of treatment efficacy. The fucosylation process requires GDP-L-fucose, fucosyltransferases, and fucosidases.
Michael Williames Leal Quirino +7 more
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Development, Characterization, and Immunomodulatory Evaluation of Carvacrol-loaded Nanoemulsion
Molecules, 2021 Carvacrol (CV) is an essential oil with numerous therapeutic properties, including immunomodulatory activity. However, this effect has not been studied in nanoemulsion systems.
Amanda Gabrielle Barros Dantas +6 more
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Synthetic thiophenes induce chromosomal damage and trigger apoptosis in human cancer cell lines
European Journal of Medicinal Chemistry Reports, 2022 Thiophenes are heterocyclic compounds containing a five-membered ring with sulphur as the heteroatom. This class of substances has been shown to have several biological activities, including specific anti-proliferative effects against some cancer cell ...
Filipe N. Franco +10 more
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Excessive daytime sleepiness in adolescents: current treatment strategies [PDF]
Sleep Science, 2020 The complaints of excessive daytime sleepiness are very common among adolescents. In addition, in this particular subpopulation, the presence of excessive daytime sleepiness is associated with negative impact on school ...
Matthieu Hein +3 more
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Galectins as pivotal components in oncogenesis and immune exclusion in human malignancies
Frontiers in Immunology, 2023 Galectins are galactoside-binding proteins, exerting numerous functions inside and outside the cell, particularly conferring adaptation to stress factors. For most of them, aberrant expression profiles have been reported in the context of cancer.
Nikiforos-Ioannis Kapetanakis +1 more
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Role of Vγ9vδ2 T lymphocytes in infectious diseases
Frontiers in Immunology, 2022 The T cell receptor Vγ9Vδ2 T cells bridge innate and adaptive antimicrobial immunity in primates. These Vγ9Vδ2 T cells respond to phosphoantigens (pAgs) present in microbial or eukaryotic cells in a butyrophilin 3A1 (BTN3) and butyrophilin 2A1 (BTN2A1 ...
Laetitia Gay +11 more
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Insulin resistance in ischemic stroke: Mechanisms and therapeutic approaches
Frontiers in Endocrinology, 2022 The pathological condition of insulin resistance prevents the neuroprotective effects of insulin. Numerous studies have demonstrated that insulin resistance, as an independent risk factor for ischemic stroke, accelerates the formation of thrombosis and ...
Peng-Fei Ding +11 more
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