Results 1 to 10 of about 1,011,230 (120)

alpha2,3 sialic acid processing enzymes expression in gastric cancer tissues reveals that ST3Gal3 but not Neu3 are associated with Lauren's classification, angiolymphatic invasion and histological grade

open access: yesEuropean Journal of Histochemistry, 2022
Gastric cancer (GC) is one of the leading causes of cancer-related deaths worldwide. Despite progress in the last decades, there are still no reliable biomarkers for the diagnosis of and prognosis for GC.
Michael W.L. Quirino   +7 more
doaj   +1 more source

FUCA2 and TSTA3 expression in gastric cancer: candidate biomarkers of malignant transformation

open access: yesFolia Histochemica et Cytobiologica, 2022
INTRODUCTION: Aberrant fucosylation is closely related to malignant transformation, cancer detection, and evaluation of treatment efficacy. The fucosylation process requires GDP-L-fucose, fucosyltransferases, and fucosidases.
Michael Williames Leal Quirino   +7 more
doaj   +1 more source

Development, Characterization, and Immunomodulatory Evaluation of Carvacrol-loaded Nanoemulsion

open access: yesMolecules, 2021
Carvacrol (CV) is an essential oil with numerous therapeutic properties, including immunomodulatory activity. However, this effect has not been studied in nanoemulsion systems.
Amanda Gabrielle Barros Dantas   +6 more
doaj   +1 more source

Synthetic thiophenes induce chromosomal damage and trigger apoptosis in human cancer cell lines

open access: yesEuropean Journal of Medicinal Chemistry Reports, 2022
Thiophenes are heterocyclic compounds containing a five-membered ring with sulphur as the heteroatom. This class of substances has been shown to have several biological activities, including specific anti-proliferative effects against some cancer cell ...
Filipe N. Franco   +10 more
doaj   +1 more source

Excessive daytime sleepiness in adolescents: current treatment strategies [PDF]

open access: yesSleep Science, 2020
The complaints of excessive daytime sleepiness are very common among adolescents. In addition, in this particular subpopulation, the presence of excessive daytime sleepiness is associated with negative impact on school ...
Matthieu Hein   +3 more
doaj   +1 more source

Galectins as pivotal components in oncogenesis and immune exclusion in human malignancies

open access: yesFrontiers in Immunology, 2023
Galectins are galactoside-binding proteins, exerting numerous functions inside and outside the cell, particularly conferring adaptation to stress factors. For most of them, aberrant expression profiles have been reported in the context of cancer.
Nikiforos-Ioannis Kapetanakis   +1 more
doaj   +1 more source

Role of Vγ9vδ2 T lymphocytes in infectious diseases

open access: yesFrontiers in Immunology, 2022
The T cell receptor Vγ9Vδ2 T cells bridge innate and adaptive antimicrobial immunity in primates. These Vγ9Vδ2 T cells respond to phosphoantigens (pAgs) present in microbial or eukaryotic cells in a butyrophilin 3A1 (BTN3) and butyrophilin 2A1 (BTN2A1 ...
Laetitia Gay   +11 more
doaj   +1 more source

Insulin resistance in ischemic stroke: Mechanisms and therapeutic approaches

open access: yesFrontiers in Endocrinology, 2022
The pathological condition of insulin resistance prevents the neuroprotective effects of insulin. Numerous studies have demonstrated that insulin resistance, as an independent risk factor for ischemic stroke, accelerates the formation of thrombosis and ...
Peng-Fei Ding   +11 more
doaj   +1 more source

The total terpenoids of (TTC) inhibit NOX-dependent formation of PMA-induced neutrophil extracellular traps (NETs)

open access: yesEuropean Journal of Inflammation, 2018
Previously, we identified that Celastrus orbiculatus , a traditional Chinese herbal medicine, exhibited prominent anti-inflammatory and anti-tumor activities.
Li Tao, Min Xu, Yanqing Liu
doaj   +1 more source

SARS‐CoV‐2 modulation of RIG‐I‐MAVS signaling: Potential mechanisms of impairment on host antiviral immunity and therapeutic approaches

open access: yesMedComm – Future Medicine, 2022
The coronavirus disease 2019 (COVID‐19) is a global infectious disease aroused by RNA virus severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2).
Mingming Wang   +3 more
doaj   +1 more source

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