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Gastric cancer (GC) is one of the leading causes of cancer-related deaths worldwide. Despite progress in the last decades, there are still no reliable biomarkers for the diagnosis of and prognosis for GC.
Michael W.L. Quirino +7 more
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FUCA2 and TSTA3 expression in gastric cancer: candidate biomarkers of malignant transformation
INTRODUCTION: Aberrant fucosylation is closely related to malignant transformation, cancer detection, and evaluation of treatment efficacy. The fucosylation process requires GDP-L-fucose, fucosyltransferases, and fucosidases.
Michael Williames Leal Quirino +7 more
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Development, Characterization, and Immunomodulatory Evaluation of Carvacrol-loaded Nanoemulsion
Carvacrol (CV) is an essential oil with numerous therapeutic properties, including immunomodulatory activity. However, this effect has not been studied in nanoemulsion systems.
Amanda Gabrielle Barros Dantas +6 more
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Synthetic thiophenes induce chromosomal damage and trigger apoptosis in human cancer cell lines
Thiophenes are heterocyclic compounds containing a five-membered ring with sulphur as the heteroatom. This class of substances has been shown to have several biological activities, including specific anti-proliferative effects against some cancer cell ...
Filipe N. Franco +10 more
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Excessive daytime sleepiness in adolescents: current treatment strategies [PDF]
The complaints of excessive daytime sleepiness are very common among adolescents. In addition, in this particular subpopulation, the presence of excessive daytime sleepiness is associated with negative impact on school ...
Matthieu Hein +3 more
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Galectins as pivotal components in oncogenesis and immune exclusion in human malignancies
Galectins are galactoside-binding proteins, exerting numerous functions inside and outside the cell, particularly conferring adaptation to stress factors. For most of them, aberrant expression profiles have been reported in the context of cancer.
Nikiforos-Ioannis Kapetanakis +1 more
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Role of Vγ9vδ2 T lymphocytes in infectious diseases
The T cell receptor Vγ9Vδ2 T cells bridge innate and adaptive antimicrobial immunity in primates. These Vγ9Vδ2 T cells respond to phosphoantigens (pAgs) present in microbial or eukaryotic cells in a butyrophilin 3A1 (BTN3) and butyrophilin 2A1 (BTN2A1 ...
Laetitia Gay +11 more
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Insulin resistance in ischemic stroke: Mechanisms and therapeutic approaches
The pathological condition of insulin resistance prevents the neuroprotective effects of insulin. Numerous studies have demonstrated that insulin resistance, as an independent risk factor for ischemic stroke, accelerates the formation of thrombosis and ...
Peng-Fei Ding +11 more
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Previously, we identified that Celastrus orbiculatus , a traditional Chinese herbal medicine, exhibited prominent anti-inflammatory and anti-tumor activities.
Li Tao, Min Xu, Yanqing Liu
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The coronavirus disease 2019 (COVID‐19) is a global infectious disease aroused by RNA virus severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2).
Mingming Wang +3 more
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