Results 241 to 250 of about 1,376,471 (276)

Measuring Intracellular Concentrations of Calcineurin Inhibitors: Expert Consensus from the International Association of Therapeutic Drug Monitoring and Clinical Toxicology (IATDMCT) Expert Panel.

Therapeutic Drug Monitoring, 2020
BACKGROUND Therapeutic drug monitoring (TDM) of the two calcineurin inhibitors (CNIs), tacrolimus (TAC) and cyclosporine A (CsA), has resulted in improvements in the management of patients who have undergone solid organ transplantation.
F. Lemaitre, N. T. Vethe, A. D’Avolio, C. Tron, Ida Robertsen, B. D. de Winter, Amedeo Denicolo, B. Koch, R. Venkataramanan, T. van Gelder, M. Brunet, S. Bergan, D. Hesselink, P. Wallemacq   +13 more
semanticscholar   +1 more source

Therapeutic drug monitoring for triazoles

Current Opinion in Infectious Diseases, 2008
Invasive fungal infections are a leading cause of morbidity and mortality in immunocompromised patients, and mechanisms to optimize therapeutic outcomes are urgently required. Therapeutic drug monitoring represents an important component for the routine use of the triazoles.Triazoles have revolutionized the prevention and treatment of invasive fungal ...
Hope, William W., Billaud, Eliane M., Lestner, Jodie, Denning, David W.   +3 more
openaire   +3 more sources

Therapeutic drug monitoring of cyclosporine

Transplantation Proceedings, 2004
Therapeutic drug monitoring of cyclosporine has been established as part of the routine clinical treatment for patients after organ transplantation. The inability to define optimal dose (maximize efficacy/minimize toxicity) has been a problem related to drug monitoring of cyclosporine.
David W. Holt, Atholl Johnston, A Jorga
openaire   +6 more sources

Review article: determination of the therapeutic range for therapeutic drug monitoring of adalimumab and infliximab in patients with inflammatory bowel disease

Alimentary Pharmacology and Therapeutics, 2020
Clinical application of therapeutic drug monitoring (TDM) to optimise anti‐TNF therapies in patients with IBD depends upon target ranges.
D. Gibson, M. Ward, C. Rentsch, A. Friedman, K. Taylor, M. Sparrow, P. Gibson   +6 more
semanticscholar   +1 more source

Therapeutic Drug Monitoring of Antiarrhythmic Drugs

Clinical Pharmacokinetics, 2003
Most antiarrhythmic drugs fulfil the formal requirements for rational use of therapeutic drug monitoring, as they show highly variable plasma concentration profiles at a given dose and a direct concentration-effect relationship. Therapeutic ranges for antiarrhythmic drugs are, however, often very poorly defined.
Jens Peter Kampmann, Gesche Jürgens, Niels Graudal   +2 more
openaire   +3 more sources

Glucuronidation in therapeutic drug monitoring

Clinica Chimica Acta, 2005
Glucuronidation is a major drug-metabolizing reaction in humans. A pharmacological effect of glucuronide metabolites is frequently neglected and the value of therapeutic drug monitoring has been questioned. However, this may not always be true.In this review the impact of glucuronidation on therapeutic drug monitoring has been evaluated on the basis of
Maria Shipkova, Eberhard Wieland
openaire   +3 more sources

Overview of therapeutic drug monitoring and clinical practice.

Talanta: The International Journal of Pure and Applied Analytical Chemistry, 2023
Zijun Fang, He Zhang, Jiuchuan Guo, Jinhong Guo   +3 more
semanticscholar   +1 more source

[Therapeutic drug monitoring of antimicrobials].

Nederlands tijdschrift voor geneeskunde, 2014
Contains fulltext : 136169.pdf (Publisher’s version ) (Closed access)
Mouton, J.W., Aarnoutse, R.E.
openaire   +3 more sources

Therapeutic Drug Monitoring in Saliva

Clinical Pharmacokinetics, 1978
The observation that drug concentrations in saliva are often proportional to the concentrations in plasma has led to the suggestion that in therapeutic drug monitoring, or in pharmacokinetic studies in general, saliva might be substituted for plasma.
Meindert Danhof, D. D. Breimer
openaire   +3 more sources

Therapeutic Drug Monitoring of the Antimycobacterial Drugs

Clinics in Laboratory Medicine, 1996
Because MDR tuberculosis and MAC are difficult to treat, TDM with the antimycobacterial drugs has become the standard of practice at NJC. By combining specific and sensitive assays, carefully collected samples, and clinical expertise, we are able to control and optimize antimycobacterial drug therapy.
openaire   +3 more sources