Results 31 to 40 of about 3,654,817 (358)

Three-Dimensional (3D) Printed Microneedles for Microencapsulated Cell Extrusion [PDF]

open access: yes, 2018
Cell-hydrogel based therapies offer great promise for wound healing. The specific aim of this study was to assess the viability of human hepatocellular carcinoma (HepG2) cells immobilized in atomized alginate capsules (3.5% (w/v) alginate, d = 225 µm ...
Bouzos, Evangelia   +6 more
core   +3 more sources

The introduction of biosimilars of low molecular weight heparins in Europe: a critical review and reappraisal endorsed by the Italian Society for Haemostasis and Thrombosis (SISET) and the Italian Society for Angiology and Vascular Medicine (SIAPAV)

open access: yesThrombosis Journal, 2017
Recently, the European Medicines Agency (EMA) authorized the introduction and marketing of Thorinane® and Inhixa®, biosimilars of the Low Molecular Weight Heparin (LMWH) enoxaparin.
Davide Imberti   +3 more
doaj   +1 more source

Case report: inability to achieve a therapeutic dose of tacrolimus in a pediatric allogeneic stem cell transplant patient after generic substitution

open access: yesBMC Pharmacology and Toxicology, 2014
BackgroundTacrolimus is an immunosuppressive drug that is used to lower the activity of the patient’s immune system to prevent organ rejection. Unfortunately, there is limited data regarding the therapeutic equivalency of generic tacrolimus formulations ...
A. Madian   +3 more
semanticscholar   +1 more source

Circadian rest-activity rhythms predict cognitive function in early Parkinson's disease independently of sleep [PDF]

open access: yes, 2018
BACKGROUND: Cognitive impairment is a common and debilitating symptom of Parkinson's disease (PD), and its etiology is likely multifactorial. One candidate mechanism is circadian disruption. Although there is evidence of circadian abnormalities in PD, no
Cronin-Golomb, Alice   +4 more
core   +1 more source

Synthesis and therapeutic potential of imidazole containing compounds

open access: yesBMC Chemistry, 2021
Imidazole is a five-membered heterocyclic moiety that possesses three carbon, two nitrogen, four hydrogen atoms, and two double bonds. It is also known as 1, 3-diazole.
Ankit Siwach, P. Verma
semanticscholar   +1 more source

The impact of motor symptoms on self-reported anxiety in Parkinson's disease [PDF]

open access: yes, 2017
OBJECTIVE: Anxiety is commonly endorsed in Parkinson's disease (PD) and significantly affects quality of life. The Beck Anxiety Inventory (BAI) is often used but contains items that overlap with common PD motor symptoms (e.g., “hands trembling”). Because
Cronin-Golomb, A.   +3 more
core   +1 more source

Human skin dermis-derived fibroblasts are a kind of functional mesenchymal stromal cells: judgements from surface markers, biological characteristics, to therapeutic efficacy

open access: yesCell & Bioscience, 2022
Human mesenchymal stromal cells (MSCs) have been widely advocated to clinical use. Human skin dermis-derived fibroblasts shared similar cellular morphology and biological characteristics to MSCs, while it still keeps elusive whether fibroblasts are ...
Chenxu Tai   +7 more
semanticscholar   +1 more source

Determination of captopril by hplctandem mass spectrometry: application in a bioequivalence study [PDF]

open access: yesRevista Brasileira em Promoção da Saúde, 2012
Objective: To assess three different captopril tablet formulations of 25mg for their bioavailability (Capoten® as the reference formulation and Captopril from FURP and Farmanguinhos as the test formulations) in 24 healthy volunteers of both sexes ...
Aline Kércia Alves Soares   +4 more
doaj  

Retroviral Replicating Vector Delivery of miR-PDL1 Inhibits Immune Checkpoint PDL1 and Enhances Immune Responses In Vitro

open access: yesMolecular Therapy: Nucleic Acids, 2017
Tumor cells express a number of immunosuppressive molecules that can suppress anti-tumor immune responses. Efficient delivery of small interfering RNAs to treat a wide range of diseases including cancers remains a challenge.
Amy H. Lin   +7 more
doaj   +1 more source

Nutritional and Behavioral Intervention for Long‐Term Childhood Acute Leukemia Survivors With Metabolic Syndrome

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Metabolic syndrome (MetS) is a common complication in survivors of childhood acute lymphoblastic and myeloid leukemia (AL), and a major risk factor for premature cardiovascular disease, type‐2‐diabetes, and metabolic dysfunction‐associated steatotic liver disease (MASLD).
Visentin Sandrine   +10 more
wiley   +1 more source

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