Inter-rater reliability of post-arrest cerebral performance category (CPC) scores. [PDF]
PURPOSE: Cerebral Performance Category (CPC) scores are often an outcome measure for post-arrest neurologic function, collected worldwide to compare performance, evaluate therapies, and formulate recommendations.
Abella, Benjamin S. +7 more
core +1 more source
Pharmacokinetics of morphine in encephalopathic neonates treated with therapeutic hypothermia
Objective Morphine is a commonly used drug in encephalopathic neonates treated with therapeutic hypothermia after perinatal asphyxia. Pharmacokinetics and optimal dosing of morphine in this population are largely unknown.
Laurent M A Favié +18 more
semanticscholar +1 more source
A pre‐cannulation survey of the circle of Willis (CoW) using transcranial Doppler (TCD) ultrasound was implemented to assess cerebral collateral circulation in children undergoing VA ECMO or cardiac surgery with cervical cannulation. The technique, in use since 2019, employs high‐end ultrasound platforms to assess brain morphology, haemorrhage and ...
Tristan Reddan +3 more
wiley +1 more source
Enhanced cancer therapy with cold-controlled drug release and photothermal warming enabled by one nanoplatform [PDF]
Stimuli-responsive nanoparticles hold great promise for drug delivery to improve the safety and efficacy of cancer therapy. One of the most investigated stimuli-responsive strategies is to induce drug release by heating with laser, ultrasound, or ...
Agarwal, Pranay +7 more
core +1 more source
ABSTRACT Lung injury is a common complication in critical sepsis. PRMT5 is implicated in endothelial inflammation and lung diseases, but its role in sepsis‐associated lung injury remains unclear. This study collected clinical sepsis samples and detected the mRNA expression of PRMT5.
Bo Wang, Zhen Ge, Fei‐Xiang Chen
wiley +1 more source
Worsening of cerebral hyperemia by the administration of terlipressin in acute liver failure with severe hepatic encephalopathy [PDF]
There is increasing evidence that terlipressin is useful in patients with cirrhosis and hepatorenal syndrome, but there are no data of its use in patients with acute liver failure (ALF) in whom hepatorenal syndrome is common.
Davies, N.A. +6 more
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A Comprehensive Update of Current Anesthesia Perspectives on Therapeutic Hypothermia
Normal thermal regulation is a result of the integration of afferent sensory, central control, and efferent responses to temperature change. Therapeutic hypothermia (TH) is a technique utilized during surgery to protect vital organs from ischemia ...
Ivan Urits +7 more
semanticscholar +1 more source
Cerebral in situ ischemic postconditioning: From bench to bedside and beyond
This review explores the translational potential of in situ ischemic postconditioning in acute ischemic stroke. Preclinical and clinical evidence is summarized to highlight its promise as a neuroprotective strategy in the era of endovascular therapy.
Xiao Jiang +4 more
wiley +1 more source
Neuroprotection Mechanisms in Cerebral Hypothermia (Review)
The review focuses on the neuroprotective mechanisms of therapeutic hypothermia from the standpoint of metabolic depression and genomic reprogramming of neurons that develop when brain temperature decreases.The concept of hypothermic pre-conditioning ...
Oleg A. Shevelev +4 more
doaj +1 more source
Elvytetyn aikuispotilaan hypotermiahoito : Hoito-ohje ja koulutus Med Group Oy:n Kuusamon toimipisteeseen [PDF]
Kammiovärinästä elvytettyjen aikuispotilaiden hypotermiahoidosta saadut tulokset viittaavat potilaiden mielekkäämpään neurologiseen toipumiseen sekä kuolleisuuden vähenemiseen. Hypotermiahoito tulisi aloittaa jo ensihoitovaiheessa. Osassa Suomea on hoito-
Lehtinen, Anni, Talja, Eveliina
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