Results 71 to 80 of about 14,507 (219)

Stains Induce Apoptosis and Autophagy in Primary and Transformed Mast Cells [PDF]

open access: yes, 2016
Statin drugs are widely employed in the clinic to reduce serum low density lipoproteins (LDLs) in patients with hypocholesteremia. In addition to their cholesterol-lowering effects through HMG CoA reductase antagonism, isoprenyl lipids necessary for ...
Paez, Patrick A
core   +1 more source

Heart rate changes after phlebotomy in polycythaemia vera and healthy donors: An observational case‐crossover pilot study

open access: yesTransfusion Medicine, EarlyView.
Abstract Background Haemoglobin plays a crucial role in oxygen transport, and any acute deviation will trigger compensatory hemodynamic functions. While the consequences of anaemia are well documented, the effects of haemoglobin reduction in individuals without anaemia remain less explored. Patients with polycythaemia vera and healthy blood donors, who
Rik P. B. Tonino   +3 more
wiley   +1 more source

The effect of therapeutic phlebotomy for hemochromatosis on non-suicidal self-injury: A case report [PDF]

open access: yesThe International Journal of Psychiatry in Medicine, 2018
Background Self-phlebotomy has been described as a form of non-suicidal self-injury. However, a relationship between non-suicidal self-injury and therapeutic phlebotomy for hemochromatosis has not previously been described. Case presentation: We present a case of a 52-year-old man in whom the frequency of his therapeutic phlebotomy and non-suicidal ...
Newham, BJC, Khanna, R
openaire   +3 more sources

The medicinal use of leeches in Malta [PDF]

open access: yes, 2002
The medical practice based on the Greek doctrine of the four humors considered that disease was due to alterations in the composition of these humors, and therapy was therefore based on attempting to restore the balance.
Savona-Ventura, Charles   +2 more
core  

Understanding donor behaviour following a deferral for low haemoglobin: A cross‐sectional survey study

open access: yesVox Sanguinis, EarlyView.
Abstract Background and Objectives While deferral due to low haemoglobin (Hb) is known to affect donor return, how donors react to and manage low Hb is less well understood. This paper aims to (1) describe donor activities to manage low Hb, and (2) examine donor knowledge, recalled emotions, satisfaction and potential concerns, and to determine their ...
Amanda Thijsen   +3 more
wiley   +1 more source

Hereditary hemochromatosis: pathogenesis, symptoms, diagnosis and current treatment - literature review

open access: yesJournal of Education, Health and Sport
Introduction: Hereditary hemochromatosis is the most common genetic disorder in Northern Europe. It involves an overload of iron in the tissues due to a deficiency of the protein hepcidin.
Dominika Prystacka-Szar   +9 more
doaj   +1 more source

Therapeutic Depletion of Iron Stores Is Not Associated with a Reduced Hemoglobin Mass in a Hemochromatosis Patient

open access: yesCase Reports in Gastroenterology, 2016
Introduction: Hereditary hemochromatosis features a dysregulated iron absorption leading to iron overload and organ damage. The regulation of total hemoglobin mass during depletion of iron deposits by therapeutic phlebotomy has not been studied.
Nina Wrobel   +4 more
doaj   +1 more source

Novel therapeutics in myeloproliferative neoplasms

open access: yesJournal of Hematology & Oncology, 2020
Hyperactive signaling of the Janus-Associated Kinase/Signal Transducers and Activators of Transcription (JAK/STAT) pathway is central to the pathogenesis of Philadelphia-chromosome-negative myeloproliferative neoplasms (MPN), i.e., polycythemia vera (PV),
Sangeetha Venugopal, John Mascarenhas
doaj   +1 more source

Emerging agents and regimens for polycythemia vera and essential thrombocythemia

open access: yesBiomarker Research, 2021
Polycythemia vera (PV) and essential thrombocythemia (ET) are both driven by JAK-STAT pathway activation and consequently much of the recent research efforts to improve the management and outcomes of patients with these neoplasms have centered around ...
Rory M. Shallis, Nikolai A. Podoltsev
doaj   +1 more source

Skin Fragility and Hyperpigmentation in a Patient With HIV

open access: yes
JEADV Clinical Practice, EarlyView.
Catalina Retamal   +2 more
wiley   +1 more source

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