Results 191 to 200 of about 1,137,024 (297)

New Diagnostic and Therapeutic Tools for Thyroid Cancer

International Journal of Endocrinology, 2013
Eleonore Fröhlich, Richard Wahl, Barbara Czarnocka, Leonidas Duntas   +3 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Macrophages in graft-versus-host disease (GVHD): dual roles as therapeutic tools and targets. [PDF]

Clin Exp Med
Raoufi A, Soleimani Samarkhazan H, Nouri S, Khaksari MN, Abbasi Sourki P, Sargazi Aval O, Baradaran B, Aghaei M.   +7 more
europepmc   +1 more source

Specifying the Efficacy of Digital Therapeutic Tools for Depression and Anxiety: Retrospective, 2-Cohort, Real-World Analysis.

J Med Internet Res, 2023
Fundoiano-Hershcovitz Y, Breuer Asher I, Ritholz MD, Feniger E, Manejwala O, Goldstein P.   +5 more
europepmc   +1 more source

Role of antibody engineering in generation of derivatives starting from MOv19 MAb: 40 years of biological/therapeutic tools against folate receptor alfa. [PDF]

Antib Ther, 2022
Frigerio B, Montermini M, Silvana C, Figini M.   +3 more
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Peptides Evaluated In Silico, In Vitro, and In Vivo as Therapeutic Tools for Obesity: A Systematic Review. [PDF]

Int J Mol Sci
Aguiar AJFC, de Medeiros WF, da Silva-Maia JK, Bezerra IWL, Piuvezam G, Morais AHA.   +5 more
europepmc   +1 more source

Editorial: Lectins from plants, algae, fungi, bacteria and animal therapeutic tools for SARS-CoV-2 and other pathogenic enveloped viruses, in a "one-health" perspective. [PDF]

Front Cell Infect Microbiol, 2023
Van Damme EJM, Rougé P.
europepmc   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Use of microRNAs as Diagnostic, Prognostic, and Therapeutic Tools for Glioblastoma. [PDF]

Int J Mol Sci
Valle-Garcia D, Pérez de la Cruz V, Flores I, Salazar A, Pineda B, Meza-Sosa KF.   +5 more
europepmc   +1 more source