Results 121 to 130 of about 1,970,330 (303)

Updated recommendations of the International dengue Initiative expert group for CYD-TDV vaccine implementation in Latin America

, 2019
Dengue disease represents a large and growing global threat to public health, causing a significant burden to health systems of endemic countries. For countries considering vaccination as part of their Integrated Management Strategy for Prevention and ...
Giambernardino, H. I.G., Castellanos-Martinez, J. M., Delrieu, Isabelle, Avila-Aguero, Maria L., Torres, Jaime, Torres, C. N, Falleiros-Arlant, Luiza Helena, Brea, J., Gessner, Bradford D., Mascareñas, Abiel   +9 more
core   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Enrichment of Ly6Chi monocytes by multiple GM-CSF injections with HBV vaccine contributes to viral clearance in a HBV mouse model

Human Vaccines & Immunotherapeutics, 2017
Adjuvants are considered a necessary component for HBV therapeutic vaccines but few are licensed in clinical practice due to concerns about safety or efficiency.
Weidong Zhao, Xian Zhou, Gan Zhao, Qing Lin, Xianzheng Wang, Xueping Yu, Bin Wang   +6 more
doaj   +1 more source

OTUD6A‐Mediated Deubiquitination of PRDX1 Protects Against Oral Ulcer by Restoring Mitochondrial Function

Advanced Science, EarlyView.
In human oral keratinocytes, OTUD6A promoted cell migration by deubiquitinating and stabilizing PRDX1. Conversely, OTUD6A deficiency reduced PRDX1 stability, triggering mitochondrial dysfunction and aggravating OU progression. ABSTRACT Oral ulcers (OU), as the most highly prevalent and recurrent oral mucosal lesion, have an unclear pathogenesis that ...
Xiaoyu Sun, Ruiwei Jia, Xingbei Pan, Rui Huang, Jiahong Chen, Ziyi Yao, Lei Yin, Jun Ma, Hongjieliang Wang, Xinyu Huang, Yilin Ma, Yifan Ping, Yuanyuan Chen, Huining Wang, Shengbin Huang, Guang Liang   +15 more
wiley   +1 more source

PROTAC‐Engineered Protein/DNA Nanoantigen is a Potent Booster for Dendritic Cell Vaccines in Cancer Immunotherapy

Advanced Science, EarlyView.
A PROTAC‐functionalized protein/DNA‐integrated nanoantigen platform is developed to enhance dendritic cell vaccine potency. By combining a VHL‐recruiting peptide‐modified antigen with a sustained expression plasmid within CaCO3 nanoparticles, this system amplifies cross‐presentation, promotes DC maturation, and elicits robust Th1 and CTL responses ...
Peng Liu, Qiang Chen, Zhe Zhou, Yuekang Xu, Jinyao Li   +4 more
wiley   +1 more source

Therapeutic recreation in mental health, from an Australian perspective : it's not just campfires and kangaroos

, 2017
Therapeutic recreation in Australia is a developing profession; therapeutic approaches of recreation to healthcare in particular mental health are still developing in a risk aware, medicalised model of care (Pegg & Lord, 2008).
Alford, Stewart (R19505)
core  

Concomitant administration of live attenuated Japanese encephalitis chimeric virus vaccine (JE-CV) and measles, mumps, rubella (MMR) vaccine: Randomized study in toddlers in Taiwan

, 2017
Background: Japanese encephalitis (JE) is the most important cause of viral encephalitis in Asia. ;Methods: In this randomized, open-label, multicenter trial in 550 children aged 12 to 18 months in Taiwan, children received one dose of JE-CV and one dose
Huang, Li-Min;Lin, Tzou-Yien;Chiu, Cheng-Hsun;Chiu, Nan-Chang;Chen, Po-Yen;Yeh, Shu-Jen;Boaz, Mark;Hutagalung, Yanee;Bouckenooghe, Alain;Feroldi, Emmanuel, 黃立民   +1 more
core   +1 more source

Chemical Bond‐Orchestrated Energy Depletion to Augment Lung Cancer Chemo‐Immunotherapy

Advanced Science, EarlyView.
This study grafted dichloroacetic acid (DCA) into perylenediimide (PDI) skeleton via ionic or covalent bond to create novel metabolic agent PDIC‐AC and PDIC‐NAC, explicitly elaborated the underlying energy metabolism and therapeutic mechanism, and developed a promising strategy for energy metabolism‐targeting chemo‐immunotherapy by chemical bond ...
Xuejie Zhao, Yuting Liu, Xiao Huang, Liwen Zhao, Chunli Li, Yongwei Huang   +5 more
wiley   +1 more source

On the future of therapeutic vaccination in chronic hepatitis B

Future Science OA, 2019
Julio Cesar Aguilar Rubido
doaj   +1 more source

Vaccine Innovation Conference 2017

, 2017
Proceedings from the Vaccine Innovation Conference 2017, held May 10, 2017, at Hyatt Regency Hotel, Montréal, QC, Canada, Presented by: Vaccine Industry ...
Committee, Vaccine Industry, Vaccine Industry Committee   +1 more
core   +1 more source