Results 21 to 30 of about 1,970,330 (303)

Combination therapy of therapeutic antibody and vaccine or entecavir in HBV carrier mice

Frontiers in Microbiology, 2023
Chronic infection with the hepatitis B virus (HBV) is a leading causes of liver cirrhosis and hepatocellular carcinoma. However, managing HBV treatments is challenging due to the lack of effective monotherapy. Here, we present two combination approaches,
Ruoyao Qi, Ruoyao Qi, Jiali Cao, Yangtao Wu, Yangtao Wu, Xing Lei, Xing Lei, Jinhang He, Jinhang He, Liang Zhang, Liang Zhang, Rao Fu, Rao Fu, Feng Chen, Feng Chen, Yingbin Wang, Yingbin Wang, Tianying Zhang, Tianying Zhang, Ningshao Xia, Ningshao Xia, Quan Yuan   +21 more
doaj   +1 more source

Preclinical assessment of a new live attenuated Mycobacterium tuberculosis Beijing-based vaccine for tuberculosis

, 2020
Tuberculosis still claims more lives than any other pathogen, and a vaccine better than BCG is urgently needed. One of the challenges for novel TB vaccines is to protect against all Mycobacterium tuberculosis lineages, including the most virulent ones ...
권기웅, 신성재
core   +1 more source

Patient-specific dendritic cell vaccines with autologous tumor antigens in 72 patients with metastatic melanoma

Melanoma Management, 2019
Aim: Metastatic melanoma patients were treated with patient-specific vaccines consisting of autologous dendritic cells loaded with antigens from irradiated cells from short-term autologous tumor cell lines. Patients & methods: A total of 72 patients were
Robert O Dillman, Andrew N Cornforth, Edward F McClay, Carol Depriest   +3 more
doaj   +1 more source

Chikungunya: vaccines and therapeutics [PDF]

F1000Research, 2017
Chikungunya virus (CHIKV) has come to prominence as a global, re-emerging pathogen over the last two decades, progressing from sporadic, remote outbreaks to worldwide explosive epidemics. From contained, though considerable, outbreaks in the southern Indian Ocean, parts of South America and the Caribbean, CHIKV continues to be a significant pathogen in
Kothila Tharmarajah, Suresh Mahalingam, Ali Zaid   +2 more
openaire   +3 more sources

Selective bacteriophages reduce the emergence of resistant bacteria in bacteriophage-antibiotic combination therapy

Microbiology Spectrum
Escherichia coli O157:H7 is a globally important foodborne pathogen with implications for food safety. Antibiotic treatment for O157 may potentially contribute to the exacerbation of hemolytic uremic syndrome, and the increasing prevalence of antibiotic ...
Aa Haeruman Azam, Koji Sato, Kazuhiko Miyanaga, Tomohiro Nakamura, Shinjiro Ojima, Kohei Kondo, Azumi Tamura, Wakana Yamashita, Yasunori Tanji, Kotaro Kiga   +9 more
doaj   +1 more source

Analysis of immunological mechanisms exerted by HBsAg-HBIG therapeutic vaccine combined with Adefovir in chronic hepatitis B patients

Human Vaccines & Immunotherapeutics, 2017
An HBsAg-HBIG therapeutic vaccine (Yeast-derived Immune Complexes, YIC) for chronic hepatitis B (CHB) patients has undergone a series of clinical trials.
Chenliang Zhou, Chaofan Li, Guo-Zhong Gong, Shuang Wang, Ji-Ming Zhang, Dao-Zhen Xu, Li-Min Guo, Hong Ren, Min Xu, Qing Xie, Chen Pan, Jie Xu, Zhongyu Hu, Shuang Geng, Xian Zhou, Xianzheng Wang, Xiaoyu Zhou, Haili Mi, Gan Zhao, Wencong Yu, Yu-Mei Wen, Lihua Huang, Xuan-Yi Wang, Bin Wang   +23 more
doaj   +1 more source

Nonlytic Fc-fused IL-7 synergizes with Mtb32 DNA vaccine to enhance antigen-specific T cell responses in a therapeutic model of tuberculosis

, 2013
Improvement to the immunogenicity of DNA vaccines was evaluated in a Mycobacterium tuberculosis (MTB) infection mouse model examining the combined effects of nonlytic Fc-fused IL-7 DNA (IL-7-nFc) and Flt3-ligand fused Mtb32 (F-Mtb32) DNA.
조상래
core   +1 more source

Potent Therapeutic Efficacy of a Novel HPV16E7-HBcAg-Hsp65 Fusion Protein Vaccine

Vaccine Research, 2021
Introduction: Cervical cancer is the fourth leading cause of cancer death in women worldwide. Nearly all cervical cancers are resulted from high-risk Human Papillomavirus (HPV) infection. Currently, there is no available HPV-specific therapy.
Chao Zhang, Chenliang Zhou, Xiaoliang Wang, Xinxing Ma, Meijun Diao, Haitao Liu, Dan Xu, Jian Wei, Yuanxiang Jiang, Menghua Zhang, Lingyun Zhou, Jiang Fan, Ge Liu   +12 more
doaj   +1 more source

Primary and booster immune responses to SA14-14-2 Japanese encephalitis vaccine in Korean infants

, 1999
Attenuated SA14-14-2 Japanese encephalitis (JE) vaccine has been administered safely and effectively to more than 100 million children in China since 1988 and recently, licensure of the vaccine in Korea has been sought.
박민수
core   +1 more source

Effectiveness of influenza vaccine in aging and older adults: comprehensive analysis of the evidence [PDF]

, 2012
Foremost amongst the diseases preventable by vaccination is influenza. Worldwide, influenza virus infection is associated with serious adverse events leading to hospitalization, debilitating complications, and death in elderly individuals ...
Assir N, Lang, Pierre-Olivier, Govind, Sheila, Aspinall R, Mendes A, Mendes, Aline, Socquet, Jennifer, Govind S, Socquet J, Assir, Noémie, Lang PO, Aspinall, Richard   +11 more
core   +1 more source