Results 61 to 70 of about 3,300,951 (351)

New Perspectives in Therapeutic Vaccines for HPV: A Critical Review

open access: yesMedicina, 2022
Human Papillomavirus is the main cause of cervical cancer, including squamous cell carcinoma of the oropharynx, anus, rectum, penis, vagina, and vulva.
Barbara Gardella   +9 more
doaj   +1 more source

Chikungunya: vaccines and therapeutics [PDF]

open access: yesF1000Research, 2017
Chikungunya virus (CHIKV) has come to prominence as a global, re-emerging pathogen over the last two decades, progressing from sporadic, remote outbreaks to worldwide explosive epidemics. From contained, though considerable, outbreaks in the southern Indian Ocean, parts of South America and the Caribbean, CHIKV continues to be a significant pathogen in
Kothila Tharmarajah   +2 more
openaire   +3 more sources

Preclinical study and clinical trial of a novel therapeutic vaccine against multi-drug resistant tuberculosis

open access: yesHuman Vaccines & Immunotherapeutics, 2017
[Purpose] Multi-drug resistant (MDR), Mycobacterium tuberculosis (TB) is a big problem in the world. We have developed novel TB therapeutic vaccine (HVJ-E/HSP65 DNA +IL-12 DNA). [Methods and Results] DNA vaccine expressing TB heat shock protein 65 and IL-
Masaji Okada   +6 more
doaj   +1 more source

Guanylate cyclase C as a target for prevention, detection, and therapy in colorectal cancer. [PDF]

open access: yes, 2017
INTRODUCTION: Colorectal cancer remains the second leading cause of cancer death in the United States, and new strategies to prevent, detect, and treat the disease are needed.
Aka, Allison A.   +5 more
core   +2 more sources

Staphylococcus aureus Vaccine Research and Development: The Past, Present and Future, Including Novel Therapeutic Strategies

open access: yesFrontiers in Immunology, 2021
Staphylococcus aureus is one of the most important human pathogens worldwide. Its high antibiotic resistance profile reinforces the need for new interventions like vaccines in addition to new antibiotics. Vaccine development efforts against S.
Jonah Clegg   +5 more
semanticscholar   +1 more source

A Scalable Protocol for Ex Vivo Production of CAR-Engineered Human NK Cells

open access: yesMethods and Protocols
Chimeric antigen receptor-expressing NK (CAR-NK) cells represent an advancing frontier in cancer immunotherapy, building upon decades of natural killer cell research and recent breakthroughs in CAR technology.
Supreet Khanal, Nirjal Bhattarai
doaj   +1 more source

Design of a Synthetic Long Peptide Vaccine Targeting HPV-16 and -18 Using Immunoinformatic Methods

open access: yesPharmaceutics, 2023
Human papillomavirus types 16 and 18 cause the majority of cervical cancers worldwide. Despite the availability of three prophylactic vaccines based on virus-like particles (VLP) of the major capsid protein (L1), these vaccines are unable to clear an ...
Alexandru Tîrziu   +9 more
doaj   +1 more source

Evaluation of Microparticulate Ovarian Cancer Vaccine via Transdermal Route of Delivery [PDF]

open access: yes, 2016
Ovarian cancer is the fifth most commonly occurring malignancy in women, with the highest mortality rate among all the gynecological tumors. Microparticulate vaccine can serve as an immunotherapeutic approach with a promising antigenic delivery system ...
Akalkotkar, Archana   +3 more
core   +2 more sources

Therapeutic vaccines in autoimmunity [PDF]

open access: yesProceedings of the National Academy of Sciences, 2004
Similarly to prophylactic vaccines whose purpose is to prevent infectious diseases, therapeutic vaccines against autoimmune diseases are based on their similarity to the putative causes of the disease. We shall describe here two such examples: a copolymer of amino acids related to myelin basic protein, in the case of multiple sclerosis, and a peptide ...
Michael, Sela, Edna, Mozes
openaire   +2 more sources

Bioproduction of a Therapeutic Vaccine Against Human Papillomavirus in Tomato Hairy Root Cultures

open access: yesFrontiers in Plant Science, 2019
Human papillomavirus (HPV) tumor disease is a critical public health problem worldwide, especially in the developing countries. The recognized pathogenic function of E5, E6, and E7 oncoproteins offers the opportunity to devise therapeutic vaccines based ...
S. Massa   +4 more
semanticscholar   +1 more source

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