Results 1 to 10 of about 28,130 (184)

Insights into the Pathogenesis of HS and Therapeutical Approaches [PDF]

Biomedicines, 2021
Hidradenitis suppurativa (HS) is a debilitating, chronic, (auto)inflammatory disease primarily affecting apocrine gland-rich areas of the body. Although pathogenic mechanisms responsible for HS have not yet been fully elucidated, it is a multifactorial ...
Elia Rosi, Maria Thais Fastame, Ilaria Scandagli, Antonella Di Cesare, Federica Ricceri, Nicola Pimpinelli, Francesca Prignano   +6 more
doaj   +2 more sources

Case Report: Personalized Therapeutical Approaches with Lenalidomide in Del(5q): A Case Series [PDF]

Frontiers in Oncology, 2022
Myelodysplastic Syndrome (MDS) with del(5q) represents a unique WHO entity, which is often treated with lenalidomide according to standard clinical practice. Guidelines concerning treatment duration have thus far not been implemented, but rather comprise
Anna Stein, Anne Sophie Kubasch, Claudia Haferlach, Uwe Platzbecker   +3 more
doaj   +2 more sources

The Double-Edged Sword of Oxidative Stress in Skin Damage and Melanoma: From Physiopathology to Therapeutical Approaches [PDF]

Antioxidants, 2022
The skin is constantly exposed to exogenous and endogenous sources of reactive oxygen species (ROS). An adequate balance between ROS levels and antioxidant defenses is necessary for the optimal cell and tissue functions, especially for the skin, since it
Monica Emanuelli, Davide Sartini, Elisa Molinelli, Roberto Campagna, Valentina Pozzi, Eleonora Salvolini, Oriana Simonetti, Anna Campanati, Annamaria Offidani   +8 more
doaj   +2 more sources

Solitary fibrous tumour: histological discoveries, behavioural aspects, risk assessment and therapeutical approaches [PDF]

Therapeutic Advances in Medical Oncology
Solitary fibrous tumours (SFT) are fibroblastic mesenchymal tumours that can develop virtually at any site. It usually affects adults, and its incidence is estimated as 1 new case per million people per year.
Claudia Di Prata, Paolo Del Fiore, Chiara Trevisiol, Saveria Tropea, Maria-Samaritana Buzzaccarini, Marco Krengli, Giovanni Scarzello, Ilaria Cosci, Marta Sbaraglia, Benedetta Chiusole, Fabio Murtas, Marcodomenico Mazza, Antonella Brunello, Marco Rastrelli, Simone Mocellin   +14 more
doaj   +2 more sources

The knowns and unknowns of long COVID-19: from mechanisms to therapeutical approaches [PDF]

Frontiers in Immunology
The coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 has been defined as the greatest global health and socioeconomic crisis of modern times. While most people recover after being infected with the virus, a significant proportion of them
Roxana Gheorghita, Roxana Gheorghita, Iuliana Soldanescu, Andrei Lobiuc, Olga Adriana Caliman Sturdza, Olga Adriana Caliman Sturdza, Roxana Filip, Roxana Filip, Adela Constantinescu – Bercu, Adela Constantinescu – Bercu, Mihai Dimian, Mihai Dimian, Serghei Mangul, Serghei Mangul, Mihai Covasa, Mihai Covasa   +15 more
doaj   +2 more sources

Therapeutical approaches to paroxysmal hemicrania, hemicrania continua and short lasting unilateral neuralgiform headache attacks: a critical appraisal [PDF]

The Journal of Headache and Pain, 2017
Background Hemicrania continua (HC), paroxysmal hemicrania (PH) and short lasting neuralgiform headache attacks (SUNCT and SUNA) are rare syndromes with a difficult therapeutic approach.
Carlo Baraldi, Lanfranco Pellesi, Simona Guerzoni, Maria Michela Cainazzo, Luigi Alberto Pini   +4 more
doaj   +2 more sources

Obesity and lymphedema in geriatrics: combined therapeutical approaches [PDF]

BMC Geriatrics, 2010
Campisi C, Boccardo F, Campisi C, Accogli S, Campisi C   +4 more
doaj   +2 more sources

alpha2,3 sialic acid processing enzymes expression in gastric cancer tissues reveals that ST3Gal3 but not Neu3 are associated with Lauren's classification, angiolymphatic invasion and histological grade

European Journal of Histochemistry, 2022
Gastric cancer (GC) is one of the leading causes of cancer-related deaths worldwide. Despite progress in the last decades, there are still no reliable biomarkers for the diagnosis of and prognosis for GC.
Michael W.L. Quirino, Amanda P.B. Albuquerque, Maria F.D. de Souza, Antônio F. da Silva Filho, Mário R. Martins, Maira G. da Rocha Pitta, Michelly C. Pereira, Moacyr J.B. de Melo Rêgo   +7 more
doaj   +1 more source

FUCA2 and TSTA3 expression in gastric cancer: candidate biomarkers of malignant transformation

Folia Histochemica et Cytobiologica, 2022
INTRODUCTION: Aberrant fucosylation is closely related to malignant transformation, cancer detection, and evaluation of treatment efficacy. The fucosylation process requires GDP-L-fucose, fucosyltransferases, and fucosidases.
Michael Williames Leal Quirino, Amanda Pinheiro de Barros Albuquerque, Maria de Fátima Deodato de Souza, Antônio Felix da Silva Filho, Mário Rino Martins, Maira Galdino da Rocha Pitta, Michelly Cristiny Pereira, Moacyr Jesus Barreto de Melo   +7 more
doaj   +1 more source

Clinicopathological profile and management of 161 cases of actinic cheilitis [PDF]

Anais Brasileiros de Dermatologia, 2015
BACKGROUND:Actinic cheilitis (AC) is a potentially malignant disorder of the lip caused by chronic exposure to ultraviolet radiation from the sun.OBJECTIVES:To evaluate the clinical, demographic, morphological and therapeutic management in AC cases data ...
Maria Luiza Diniz de Sousa Lopes, Francisco Leonardo da Silva Júnior, Kenio Costa Lima, Patrícia Teixeira de Oliveira, Éricka Janine Dantas da Silveira   +4 more
doaj   +2 more sources