Results 21 to 30 of about 1,302,607 (412)

Genesis of an emergency public drug information website by the French Society of Pharmacology and Therapeutics during the COVID‐19 pandemic

Fundamental & Clinical Pharmacology, 2020
On March 16, 2020, the French Society of Pharmacology and Therapeutics put online a national Question and Answer (Q&A) website, https://sfpt-fr.org/covid19 on the proper use of drugs during the COVID‐19 pandemic.
Louis Larrouquere, Manon Gabin, Emmanuelle Poingt, Amelle Mouffak, A. Hlavaty, M. Lepelley, C. Khouri, A. Bellier, J. Alexandre, P. Bedouch, L. Bertoletti, R. Bordet, B. Bouhanick, A. Jonville‐Béra, S. Laporte, C. Le Jeunne, L. Létinier, J. Micallef, F. Naudet, M. Roustit, M. Molimard, Vincent Richard, J. Cracowski   +22 more
semanticscholar   +1 more source

Utilization of Physiologically Based Pharmacokinetic Modeling in Clinical Pharmacology and Therapeutics: an Overview

Current Pharmacology Reports, 2020
The purpose of this review was to assess the advancement of applications for physiologically based pharmacokinetic (PBPK) modeling in various therapeutic areas.
Courtney L Perry, Grace Davis, T. M. Conner, Tao Zhang   +3 more
semanticscholar   +1 more source

Time to Step Up: A Call to Action For the Clinical and Quantitative Pharmacology Community to Accelerate Therapeutics for COVID‐19

Clinical and Translational Science, 2020
The global response to finding therapeutics for coronavirus disease 2019 (COVID‐19) is chaotic even if well intentioned. There is an opportunity, but more importantly, an obligation for the global clinical and quantitative pharmacology community to come ...
Dan Hartman, Steven Kern, Fran Brown, Suzanne K. Minton, Craig R. Rayner   +4 more
doaj   +1 more source

Ethnomedicinal applications, phytochemistry, and pharmacological properties of Laggera aurita Linn (Asteraceae): A Review

Bulletin of the National Research Centre, 2022
Background The plant Laggera aurita (Asteraceae) is a commonly utilized medicinal plant growing as a weed in African countries used in the treatment of many diseases.
Sa’adatu Muhammad Julde, Safiya Bala Borodo, Abubakar Sadiq Wada, Mubarak Hussaini Ahmad, Sani Malami, Lawal Alhassan Bichi   +5 more
doaj   +1 more source

Network Pharmacology-Based Strategy for the Investigation of the Anti-Obesity Effects of an Ethanolic Extract of Zanthoxylum bungeanum Maxim

Frontiers in Pharmacology, 2020
Network pharmacology is considered as the next paradigm in drug discovery. In an era when obesity has become global epidemic, network pharmacology becomes an ideal tool to discover novel herbal-based therapeutics with effective anti-obesity effects ...
Ying Wang, Song Hong Yang, Keying Zhong, Ting Jiang, Mi Zhang, Hiu Yee Kwan, Tao Su   +6 more
doaj   +1 more source

Comparing the signaling and transcriptome profiling landscapes of human iPSC-derived and primary rat neonatal cardiomyocytes

Scientific Reports, 2023
The inaccessibility of human cardiomyocytes significantly hindered years of cardiovascular research efforts. To overcome these limitations, non-human cell sources were used as proxies to study heart function and associated diseases.
Kyla Bourque, Jace Jones-Tabah, Darlaine Pétrin, Ryan D. Martin, Jason C. Tanny, Terence E. Hébert   +5 more
doaj   +1 more source

Clinical Pharmacology & Therapeutics 2030

Clinical pharmacology and therapy, 2020
Welcome to the first issue of Clinical Pharmacology & Therapeutics (CPT) produced by the journals’ new editorial team (Table 1). We have chosen the theme Clinical Pharmacology and Therapeutics 2030 (Figure 1) for this occasion, to share our vision for ...
P. H. van der Graaf, K. Giacomini
semanticscholar   +1 more source

American Society for Pharmacology and Experimental Therapeutics Division for Pharmacology Education at EB2022—Meeting report

Pharmacology Research & Perspectives, 2022
The American Society for Pharmacology and Experimental Therapeutics (ASPET) held its annual meeting at the Experimental Biology 2022 conference in Philadelphia, PA on April 2–5, 2022.
Joe B. Blumer, Marieke Kruidering, Katharina Brandl, Brooks McPhail, Mark A. Simmons   +4 more
doaj   +1 more source

A pharmacological characterization of Cannabis sativa chemovar extracts

Journal of Cannabis Research, 2020
Background Cannabis contains Δ9-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD) as the primary constituents responsible for pharmacological activity.
Alykhan Devsi, Brett Kiyota, Theophile Ouellette, Andrew P. Hegle, Ricardo E. Rivera-Acevedo, Jasper Wong, Ying Dong, Michael K. Pugsley, Timothy Fung   +8 more
doaj   +1 more source

NKTR-255, a novel polymer-conjugated rhIL-15 with potent antitumor efficacy

Journal for ImmunoTherapy of Cancer, 2021
Background NKTR-255 is a novel polyethylene glycol-conjugate of recombinant human interleukin-15 (rhIL-15), which was designed to retain all known receptor binding interactions of the IL-15 molecule. We explored the biologic and pharmacologic differences
Peter Kirk, Murali Addepalli, Thomas Chang, Palakshi Obalapur, Peiwen Kuo, Phi Quach, Jonathan Zalevsky, Rhoneil Pena, Saul Kivimae, Werner Rubas, Takahiro Miyazaki, Loui Madakamutil, Mekhala Maiti, Marlene Hennessy, Sara Sheibani, Joanna Wilczek, Janet Cetz, Andrew Moffett, Yinyan Tang, Jicai Huang, Dawei Sheng   +20 more
doaj   +1 more source