Results 11 to 20 of about 1,549,234 (325)

E. PHARMACOLOGY AND THERAPEUTICS. [PDF]

The Lancet, 1897
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Leech, D. G., de Martigny, F. X. L., Spier, J. R., Marshall, C. R.   +3 more
openaire   +1 more source

Comparing the signaling and transcriptome profiling landscapes of human iPSC-derived and primary rat neonatal cardiomyocytes

Scientific Reports, 2023
The inaccessibility of human cardiomyocytes significantly hindered years of cardiovascular research efforts. To overcome these limitations, non-human cell sources were used as proxies to study heart function and associated diseases.
Kyla Bourque, Jace Jones-Tabah, Darlaine Pétrin, Ryan D. Martin, Jason C. Tanny, Terence E. Hébert   +5 more
doaj   +1 more source

Network Pharmacology-Based Strategy for the Investigation of the Anti-Obesity Effects of an Ethanolic Extract of Zanthoxylum bungeanum Maxim

Frontiers in Pharmacology, 2020
Network pharmacology is considered as the next paradigm in drug discovery. In an era when obesity has become global epidemic, network pharmacology becomes an ideal tool to discover novel herbal-based therapeutics with effective anti-obesity effects ...
Ying Wang, Song Hong Yang, Keying Zhong, Ting Jiang, Mi Zhang, Hiu Yee Kwan, Tao Su   +6 more
doaj   +1 more source

Ethnomedicinal applications, phytochemistry, and pharmacological properties of Laggera aurita Linn (Asteraceae): A Review

Bulletin of the National Research Centre, 2022
Background The plant Laggera aurita (Asteraceae) is a commonly utilized medicinal plant growing as a weed in African countries used in the treatment of many diseases.
Sa’adatu Muhammad Julde, Safiya Bala Borodo, Abubakar Sadiq Wada, Mubarak Hussaini Ahmad, Sani Malami, Lawal Alhassan Bichi   +5 more
doaj   +1 more source

Clinical Pharmacology & Therapeutics 2030

Clinical pharmacology and therapy, 2020
Welcome to the first issue of Clinical Pharmacology & Therapeutics (CPT) produced by the journals’ new editorial team (Table 1). We have chosen the theme Clinical Pharmacology and Therapeutics 2030 (Figure 1) for this occasion, to share our vision for ...
P. H. van der Graaf, K. Giacomini
semanticscholar   +1 more source

A pharmacological characterization of Cannabis sativa chemovar extracts

Journal of Cannabis Research, 2020
Background Cannabis contains Δ9-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD) as the primary constituents responsible for pharmacological activity.
Alykhan Devsi, Brett Kiyota, Theophile Ouellette, Andrew P. Hegle, Ricardo E. Rivera-Acevedo, Jasper Wong, Ying Dong, Michael K. Pugsley, Timothy Fung   +8 more
doaj   +1 more source

Clinical Pharmacology & Therapeutics: Past, Present, and Future. [PDF]

, 2017
Clinical Pharmacology & Therapeutics (CPT), the definitive and timely source for advances in human therapeutics, transcends the drug discovery, development, regulation, and utilization continuum to catalyze, evolve, and disseminate discipline ...
Terzic, Andre, Waldman, Scott A.
core   +2 more sources

The growth of siRNA-based therapeutics: updated clinical studies.

Biochemical Pharmacology, 2021
More than two decades after the natural gene-silencing mechanism of RNA interference was elucidated, small interfering RNA (siRNA)-based therapeutics have finally broken into the pharmaceutical market.
M. M. Zhang, R. Bahal, T. Rasmussen, J. Manautou, Xiao-bo Zhong   +4 more
semanticscholar   +1 more source

Advancing pharmacometrics and systems pharmacology. [PDF]

, 2012
Pharmacometrics and systems pharmacology are emerging as principal quantitative sciences within drug development and experimental therapeutics. In recognition of the importance of pharmacometrics and systems pharmacology to the discipline of clinical ...
Terzic, Andre, Waldman, Scott A.
core   +2 more sources

CGRP physiology, pharmacology, and therapeutic targets: Migraine and beyond.

Physiological Reviews, 2022
Calcitonin gene-related peptide (CGRP) is a neuropeptide with diverse physiological functions. Its two isoforms (α and β) are widely expressed throughout the body in sensory neurons, as well as in other cell types, such as motor neurons and ...
A. Russo, D. Hay
semanticscholar   +1 more source