Results 31 to 40 of about 1,302,607 (412)
Transfer of rhodamine-123 into the brain and cerebrospinal fluid of fetal, neonatal and adult rats
Fluids and Barriers of the CNS, 2021 Background Adenosine triphosphate binding cassette transporters such as P-glycoprotein (PGP) play an important role in drug pharmacokinetics by actively effluxing their substrates at barrier interfaces, including the blood-brain, blood-cerebrospinal ...
Liam M. Koehn +4 more
doaj +1 more source
Identification and Molecular Dynamic Simulation of Flavonoids from Mediterranean species of Oregano against the Zika NS2B-NS3 Protease [PDF]
World Journal of Pharmaceutical Research, Volume 11, Issue 15,
Page 1236-1259, Year 2022, 2022 The Zika virus, is an emerging infectious disease causing severe complications such as microcephaly in infants and Guillain Barre syndrome in adults. There is no licensed vaccination or approved medicine to treat ZIKV infection. Therefore, extensive research is being carried out to find compounds that can be used effectively as therapeutic molecules to
arxiv +1 more source
Peer Review Certifies Quality and Innovation in Clinical Pharmacology & Therapeutics. [PDF]
, 2017 Clinical Pharmacology & Therapeutics (CPT) is an established voice of the discipline, a trusted source of new knowledge showcasing discovery, translation, and application of novel therapeutic paradigms to advance the management of patients and ...
Terzic, Andre M., Waldman, Scott A.
core +2 more sources
Curcumin as a Natural Remedy for Atherosclerosis: A Pharmacological Review
Molecules, 2021 Curcumin, a natural polyphenolic compound present in Curcuma longa L. rhizomes, shows potent antioxidant, anti-inflammatory, anti-cancer, and anti-atherosclerotic properties.
Laxman Singh +4 more
doaj +1 more source
RNAi-Based Therapeutics and Novel RNA Bioengineering Technologies
Journal of Pharmacology and Experimental Therapeutics, 2022 RNA interference (RNAi) provides researchers with a versatile means to modulate target gene expression. The major forms of RNAi molecules, genome-derived microRNAs (miRNAs) and exogenous small interfering RNAs (siRNAs), converge into RNA-induced ...
G. Traber, A. Yu
semanticscholar +1 more source
Bulletin of the National Research Centre, 2022 Background Eragrostis tremula Hochst. ex Steud. (Poaceae) is used in ethno-medicine as a memory enhancer. Studies have shown that the whole plant possesses memory enhancing potentials and could be beneficial in the management of amnesia and cognitive ...
Abdullahi Balarabe Nazifi +4 more
doaj +1 more source
Psychedelics as Transformative Therapeutics.
American Journal of Psychiatry, 2023 Over the past decade, psychedelic compounds have emerged as potentially transformative therapeutics for a variety of intractable neuropsychiatric conditions.
B. Roth, R. Gumpper
semanticscholar +1 more source
Nature Communications, 2020 C-terminal binding protein (CtBP) interacting protein (CtIP) is a fundamental factor for the initiation of DNA end resection to initiate DNA repair. Here the authors reveal mechanistic insights into the regulation of CtIP via the deubiquitinase USP52.
Ming Gao +12 more
doaj +1 more source
CGRP physiology, pharmacology, and therapeutic targets: Migraine and beyond.
Physiological Reviews, 2022 Calcitonin gene-related peptide (CGRP) is a neuropeptide with diverse physiological functions. Its two isoforms (α and β) are widely expressed throughout the body in sensory neurons, as well as in other cell types, such as motor neurons and ...
A. Russo, D. Hay
semanticscholar +1 more source
Forensic pharmacology: An important and evolving subspecialty needs recognition in India
Journal of Pharmacy and Bioallied Sciences, 2016 With training in pharmacology, a pharmacologist has an expert knowledge as well as working experience in the subjects of therapeutics, pharmacokinetics, and toxicology along with exposure to subjects such as forensic medicine during the medical education.
Harshad Onkarrao Malve
doaj +1 more source