Results 91 to 100 of about 1,594,004 (375)
TrkB-Targeted Therapy for Mucoepidermoid Carcinoma
Biomedicines, 2020 The brain-derived neurotrophic factor (BDNF)/tyrosine receptor kinase B (TrkB) pathway was previously associated with key oncogenic outcomes in a number of adenocarcinomas.
Vivian P. Wagner +8 more
doaj +1 more source
Acceptability of prophylactic treatment against COVID-19 by paramedics
European Psychiatry, 2021 Introduction The year 2020 was marked by the COVID-19 pandemic that killed more than one million people. Scientists around the world are looking for prophylactic treatment against this virus.
H. El Kefi +6 more
doaj +1 more source
Current status and future directions of botulinum neurotoxins for targeting pain processing. [PDF]
, 2015 Current evidence suggests that botulinum neurotoxins (BoNTs) A1 and B1, given locally into peripheral tissues such as skin, muscles, and joints, alter nociceptive processing otherwise initiated by inflammation or nerve injury in animal models and humans.
Pellett, Sabine +2 more
core +2 more sources
FEBS Letters, EarlyView.The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley +1 more source
Communications BiologyXRN1 (5’-3’ exoribonuclease 1) degrades RNA from the 5′ → 3′ direction and utilizes both single- and double-stranded RNA as substrates. XRN1 plays a critical role in mRNA turnover as well as regulating the cellular response to viral infection.
Gordon J. Lockbaum +21 more
doaj +1 more source
Cancer Medicine, 2020 Background The incidence of male breast cancer (MBC), although rare, has shown an increase. However, the current epidemiology of and practice patterns for MBC remain unclear.
Taisuke Ishii +3 more
doaj +1 more source
Exploring Virulence Factors and Alternative Therapies against Staphylococcus aureus Pneumonia
Toxins, 2020 Pneumonia is an acute pulmonary infection associated with high mortality and an immense financial burden on healthcare systems. Staphylococcus aureus is an opportunistic pathogen capable of inducing S.
Jelle Vlaeminck +7 more
doaj +1 more source
Pediatric Obesity: Influence on Drug Dosing and Therapeutics [PDF]
, 2018 Obesity is an ongoing global health concern and has only recently been recognized as a chronic disease of energy homeostasis and fuel partitioning. Obesity afflicts 17% of US children and adolescents.
Ameer, Barbara, PharmD, MBA, BCPS, FCP +1 more
core +1 more source
Investigating the functionality of an OCT4-short response element in human induced pluripotent stem cells. [PDF]
, 2016 Pluripotent stem cells offer great therapeutic promise for personalized treatment platforms for numerous injuries, disorders, and diseases. Octamer-binding transcription factor 4 (OCT4) is a key regulatory gene maintaining pluripotency and self-renewal ...
Awe, Jason P +9 more
core +3 more sources