Results 101 to 110 of about 1,055,467 (319)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
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BioengineeringObjectives: This study’s purpose is to investigate the lumbar biomechanical effects of unilateral partial facetectomy (UPF) of different facet joint (FJ) portions under percutaneous endoscopy.
Tao Ma +4 more
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, 2008 Therapeutics Letter 70 summarizes the top five most accessed Cochrane reviews in 2007. Topics include prevention of fall in elderly people, treating obesity in children, low glycaemic diets for overweight and obesity, and nicotine receptor partial ...
Therapeutics Initiative (University of British Columbia)
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Current Issues in Molecular BiologyAcute lymphoblastic leukemia (ALL) is the most common childhood cancer, with pediatric ALL having a ~90 percent cure rate, while the adult cure rate is considerably lower.
Makayla R. K. Wilkins, Brett E. Pickett
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, 1994 Therapeutics Letter 1 addresses common questions, including dosage, about H2-blockers for treatment of non-ulcer dyspepsia in adults. Other than cost, there is little difference between the four H2-blockers (Cimetidine, Famotidine, Nizatidine, and ...
Therapeutics Initiative (University of British Columbia)
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Neutrophils in Myocarditis: A Focus on the Secretory and Phagocytotic Functions
Reviews in Cardiovascular MedicineMyocarditis is a life-threatening inflammatory disorder that affects the cardiac muscle tissue. Current treatments merely regulate heart function but fail to tackle the root cause of inflammation.
Lisha Jia +4 more
doaj +1 more source
, 1999 Therapeutics Letter 28 explores the role of angiotensin II receptor blockers in hypertension and congestive heart failure. Conclusions: Angiotensin receptor blockers act to modulate the renin angiotensin pathway at a different site compared to ACE ...
Therapeutics Initiative (University of British Columbia)
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