Results 111 to 120 of about 1,055,467 (319)
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Therapeutics Letter 11 reviews the treatment of transient and chronic insomnia in the primary care setting. Conclusions: Manage insomnia in your practice by education and encouragement of appropriate sleep habits.
Therapeutics Initiative (University of British Columbia)
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The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Viral infectious diseases continue to pose significant public health threats, driving severe epidemics and occasional pandemics of great consequences to humans. Viral infections trigger a range of transcriptional and epitranscriptional changes, including
Mahmoud Bayoumi +4 more
doaj +1 more source
Therapeutics Letter 66 provides an update on the prescription drug treatments for overactive bladder that were previously reviewed in Therapeutics Letter 57.
Therapeutics Initiative (University of British Columbia)
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Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Therapeutics Letter 7 examines drugs of choice for the treatment of hypertension. Conclusions: based on the evidence available at this time and using criteria of effectiveness and cost, thiazides are clearly the drug of first choice.
Therapeutics Initiative (University of British Columbia)
core

