Results 131 to 140 of about 1,064,547 (319)
Therapeutics Letter 97 examines intravenous (IV) iron for severe iron deficiency. Conclusions Intravenous iron markedly benefits appropriately selected people with chronic severe iron deficiency.
Therapeutics Initiative (University of British Columbia)
core
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Therapeutics Letter 45 considers the value of single stereoisomer drugs. Stereoisomers are molecules with one or more “chiral” centres that allow the possibility of forms with the same chemical formula but differing spatial arrangements. The concept that
Therapeutics Initiative (University of British Columbia)
core
Aumento del uso de nuevos antipsicóticos en niños: ¿Debemos preocuparnos?
nan Therapeutics Initiative
doaj +1 more source
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Therapeutics Letter 42 explores the reporting of serious adverse events (SAEs) using examples from lipid-lowering trials. Conclusions: Total %SAEs is an important measure of the health impact of a drug.
Therapeutics Initiative (University of British Columbia)
core
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Therapeutics Letter 119 discusses epinephrine autoinjectors available in Canada. Conclusions People at risk for anaphylaxis in the outpatient setting should be advised to have access to at least two epinephrine autoinjectors especially when they are far ...
Therapeutics Initiative (University of British Columbia)
core
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Therapeutics Letter 56 examines drugs for Alzheimer's disease. Conclusions: Donepezil has not been demonstrated to improve outcomes of importance to patients and caregivers (e.g. institutionalization or disability).
Therapeutics Initiative (University of British Columbia)
core

