Results 131 to 140 of about 1,064,547 (319)

Therapeutics Letter 97 [PDF]

open access: yes, 2015
Therapeutics Letter 97 examines intravenous (IV) iron for severe iron deficiency. Conclusions Intravenous iron markedly benefits appropriately selected people with chronic severe iron deficiency.
Therapeutics Initiative (University of British Columbia)
core  

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Therapeutics Letter 45 [PDF]

open access: yes, 2002
Therapeutics Letter 45 considers the value of single stereoisomer drugs. Stereoisomers are molecules with one or more “chiral” centres that allow the possibility of forms with the same chemical formula but differing spatial arrangements. The concept that
Therapeutics Initiative (University of British Columbia)
core  

Aumento del uso de nuevos antipsicóticos en niños: ¿Debemos preocuparnos?

open access: yesEvidencia. Actualización en la Práctica Ambulatoria, 2010
nan Therapeutics Initiative
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Therapeutics Letter 42 [PDF]

open access: yes, 2001
Therapeutics Letter 42 explores the reporting of serious adverse events (SAEs) using examples from lipid-lowering trials. Conclusions: Total %SAEs is an important measure of the health impact of a drug.
Therapeutics Initiative (University of British Columbia)
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Therapeutics Letter 119 [PDF]

open access: yes, 2019
Therapeutics Letter 119 discusses epinephrine autoinjectors available in Canada. Conclusions People at risk for anaphylaxis in the outpatient setting should be advised to have access to at least two epinephrine autoinjectors especially when they are far ...
Therapeutics Initiative (University of British Columbia)
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Therapeutics Letter 56 [PDF]

open access: yes, 2005
Therapeutics Letter 56 examines drugs for Alzheimer's disease. Conclusions: Donepezil has not been demonstrated to improve outcomes of importance to patients and caregivers (e.g. institutionalization or disability).
Therapeutics Initiative (University of British Columbia)
core  

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