Results 11 to 20 of about 1,553,588 (375)
The American Journal of the Medical Sciences, 1905 n ...
Wilcox, Reynold Webb +1 more
openaire +2 more sources
The American Journal of the Medical Sciences, 1900 n ...
REYNOLD WEBB WILCOX, SMITH ELY JELLIFFE
openaire +2 more sources
The American Journal of The Medical Sciences, 1920 n ...
Lambert, Samuel W., Lieb, Charles C.
openaire +1 more source
Dual inhibition of αvβ6 and αvβ1 reduces fibrogenesis in lung tissue explants from patients with IPF
Respiratory Research, 2021 Rationale αv integrins, key regulators of transforming growth factor-β activation and fibrogenesis in in vivo models of pulmonary fibrosis, are expressed on abnormal epithelial cells (αvβ6) and fibroblasts (αvβ1) in fibrotic lungs.
Martin L. Decaris +27 more
doaj +1 more source
PEGylated therapeutics in the clinic
Bioengineering & Translational Medicine, 2023 The covalent attachment of polyethylene glycol (PEG) to therapeutic agents, termed PEGylation, is a well‐established and clinically proven drug delivery approach to improve the pharmacokinetics and pharmacodynamics of drugs.
Yongsheng Gao +3 more
semanticscholar +1 more source
A spoonful of sugar: the application of glycopolymers in therapeutics [PDF]
, 2011 Glycopolymers, synthetic polymers displaying carbohydrate moieties, have been linked to many potential applications at the biology–chemistry interface. One area that holds particular promise is the employment of glycopolymers as vehicles for therapeutics
Cameron, Neil R., Spain, Sebastian G.
core +2 more sources
RNA-based therapeutics: an overview and prospectus
Cell Death and Disease, 2022 The growing understanding of RNA functions and their crucial roles in diseases promotes the application of various RNAs to selectively function on hitherto “undruggable” proteins, transcripts and genes, thus potentially broadening the therapeutic targets.
Yiran Zhu +3 more
semanticscholar +1 more source
OncoImmunology, 2021 Co-stimulatory 4–1BB receptors on tumor-infiltrating T cells are a compelling target for overcoming resistance to immune checkpoint inhibitors, but initial clinical studies of 4–1BB agonist mAbs were accompanied by liver toxicity. We sought to engineer a
Stefan Warmuth +23 more
doaj +1 more source
Pregabalin: a range of misuse-related unanswered questions [PDF]
, 2019 © 2019 The Authors.
Chiappini, Stephania, Schifano, Fabrizio
core +2 more sources
Engineering the next generation of cell-based therapeutics
Nature reviews. Drug discovery, 2022 Cell-based therapeutics are an emerging modality with the potential to treat many currently intractable diseases through uniquely powerful modes of action.
C. Bashor +4 more
semanticscholar +1 more source