Results 11 to 20 of about 1,429,081 (399)
The American Journal of The Medical Sciences, 1920 n ...
Lambert, Samuel W., Lieb, Charles C.
openaire +1 more source
Journal of Neuroinflammation, 2021 Background Inflammation in the central nervous system (CNS) is observed in many neurological disorders. Nitric oxide-soluble guanylate cyclase-cyclic guanosine monophosphate (NO–sGC–cGMP) signaling plays an essential role in modulating neuroinflammation.
Susana S. Correia +16 more
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Avulsion injuries: an update on radiologic findings [PDF]
Yeungnam University Journal of Medicine, 2021 Avulsion injuries result from the application of a tensile force to a musculoskeletal unit or ligament. Although injuries tend to occur more commonly in skeletally immature populations due to the weakness of their apophysis, adults may also be subject to
Changwon Choi +4 more
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, 2020 The CNS Neuroscience & Therapeutics provides a medium for rapid publication of original clinical, experimental, and translational research papers, timely reviews, and reports of novel findings of therapeutic relevance to the central nervous system.
Boltze, Johannes +8 more
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RNA-based therapeutics: an overview and prospectus
Cell Death and Disease, 2022 The growing understanding of RNA functions and their crucial roles in diseases promotes the application of various RNAs to selectively function on hitherto “undruggable” proteins, transcripts and genes, thus potentially broadening the therapeutic targets.
Yiran Zhu +3 more
semanticscholar +1 more source
Dual inhibition of αvβ6 and αvβ1 reduces fibrogenesis in lung tissue explants from patients with IPF
Respiratory Research, 2021 Rationale αv integrins, key regulators of transforming growth factor-β activation and fibrogenesis in in vivo models of pulmonary fibrosis, are expressed on abnormal epithelial cells (αvβ6) and fibroblasts (αvβ1) in fibrotic lungs.
Martin L. Decaris +27 more
doaj +1 more source
Conversational Agents in Therapeutic Interventions for Neurodevelopmental Disorders: A Survey [PDF]
, 2021 Neurodevelopmental Disorders (NDD) are a group of conditions with onset in the developmental period characterized by deficits in the cognitive and social areas. Conversational agents have been increasingly explored to support therapeutic interventions for people with NDD.
arxiv +1 more source
Drug delivery systems for RNA therapeutics
Nature reviews genetics, 2022 RNA-based gene therapy requires therapeutic RNA to function inside target cells without eliciting unwanted immune responses. RNA can be ferried into cells using non-viral drug delivery systems, which circumvent the limitations of viral delivery vectors ...
Kalina Paunovska +2 more
semanticscholar +1 more source
Big Hopes with Small Molecules – PIQUR Therapeutics AG is aiming to Turn Cancer into a Manageable Disease [PDF]
, 2014 The origins of PIQUR Therapeutics AG, which was established in 2011, are found in significant research work at the University of Basel. The main focus of the spin-off of the University of Basel is the active pharmaceutical ingredient PQR309, which was ...
PIQUR Therapeutics AG
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Oncogenesis, 2023 Chimeric antigen receptor T-cell (CAR-T) therapy has demonstrated potent clinical efficacy in the treatment of hematopoietic malignancies. However, the application of CAR-T in solid tumors has been limited due in part to the expression of inhibitory ...
Zhao Chen +25 more
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