Results 71 to 80 of about 305,051 (312)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Toward a deeper understanding of the thermal degradation mechanism of nanocellulose

, 2017
Understanding the thermal degradation process of cellulose-nanofibers (CNF) is necessary for developing high-value added CNF-based materials with e.g. fire retardant properties or high thermal stability.
Nathalie Lavoine, Lichtenstein, Karin,, Karin Lichtenstein, Lavoine, Nathalie,   +3 more
core   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Analytical methods for assessing paper degradation In transformers [PDF]

, 2006
Power transformers are essential equipments for distributing electricity. However, maintenance of these equipments is necessary to ensure long working life and to avoid catastrophic incidents.
Christofidis, Stavros
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

A study of poly(vinyl alcohol) thermal degradation by thermogravimetry and differential thermogravimetry

Ingeniería e Investigación, 2007
The thermal degradation of poly(vinyl alcohol) (PVA) having different degrees of hydrolysis and molecular weights was studied by thermogravimetry (TGA) and differential thermogravimetry (DTGA).
Julián Esteban Barrera, John Alexander Rodríguez, Jairo Ernesto Perilla, Néstor Ariel Algecira Enciso   +3 more
doaj  

Characterisation of the mechanical and thermal degradation behaviour of natural fibres for lightweight automotive applications

, 2013
It is well established that light-weighting of automotive parts leads to reduced carbon emissions over vehicle lifetime. Mineral fibres and fillers have a relatively high density and may require high levels of energy in their production, resulting in a ...
Liggat, John, Rudeiros Fernandez, Jose Luis, Thomason, James, Soliman, M.   +3 more
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Review : Auto-oxidation of aliphatic polyamides [PDF]

, 2013
The literature on oxidation kinetics of polyamides and model compounds has been reviewed in order to try to extract suitable information for non-empirical kinetic modeling.
GUILMENT, Jean, VERDU, Jacques, Okamba Diogo, Octavie, OKAMBA-DIOGO, Octavie, FERNAGUT, François, FAYOLLE, Bruno, RICHAUD, Emmanuel   +6 more
core   +1 more source