Results 61 to 70 of about 508,590 (314)

Experimental Evidence of the Coupling between the Energy Charge–Discharge and Natural Ventilation in a Full-Scale Passive Building

open access: yesBuildings, 2023
An experimental study was carried out on a full-scale passive building equipped with global and local instrumentation with the aim of characterizing the energy charge and discharge processes and their coupling to the outdoor thermal stresses, especially ...
Miguel Chen Austin   +5 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Reuse Waste Material and Carbon Dioxide Emissions to Save Energy and Approach Sustainable Lightweight Portable Shelters

open access: yesEnvironmental and Climate Technologies, 2020
Despite their great significance, lightweight structures have poor thermal inertia. In order to enhance the thermal comfort inside such buildings, architects need lightweight thermal storage.
Alkhalidi Ammar, Zaytoun Yara Nidal
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

COLDFARMSENS - A SMART IOT-BASED ARCHITECTURE FOR ANALYZING AND REGULATING GREENHOUSE CONDITIONS [PDF]

open access: yesProceedings on Engineering Sciences
Our research focuses on addressing the unique challenges faced by farmers in cold and arid regions. Specifically, we have developed an advanced IoT-enabled intelligent greenhouse atmosphere monitoring and alarming system called ColdFarmSens.
Rinky Dwivedi , Deepa Gupta , Arun Kumar
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

On the thermal buffering of naturally ventilated buildings through internal thermal mass

open access: yes
In this paper we examine the role of thermal mass in buffering the interior temperature of a naturally ventilated building from the diurnal fluctuations in the environment.
Woods, A. W. andy; BPI;, Holford, J. M.
core   +1 more source

Pile heat exchangers: thermal behaviour and interactions [PDF]

open access: yes, 2013
Thermal piles – that is structural foundation piles also used as heat exchangers as part of a ground energy system – are increasingly being adopted for their contribution to more sustainable energy strategies for new buildings.
Loveridge, F.A.   +3 more
core   +1 more source

Development of a Particulate Solids Thermal Mass Flowmeter

open access: yesKONA Powder and Particle Journal, 2014
An ideal mass flow meter should have the following properties: it should be non-invasive so as not to disrupt the flow profile; it should be easily installed on the conveying line to provide on-line and continuous measurements; it should be able to provide an accurate indication of the mass flow rate regardless of the orientation of the measurement ...
Mary Kato, John Pugh, Don McGlinchey
openaire   +3 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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