Results 51 to 60 of about 762,159 (346)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Physicochemical and pasting properties of corn starch as affected by hydrothermal modification by various methods

International Journal of Food Properties, 2022
Native corn starch has a lack of characteristics such as low thermal stability, low resistance to shear force, and a high tendency to retrograde. To address this problem, it needs to be modified to improve its application in the food sector. Hydrothermal
Herlina Marta, Yana Cahyana, Sarah Bintang, Giffary Pramafisi Soeherman, Mohamad Djali   +4 more
doaj   +1 more source

Influence of Thermal Modification in Nitrogen Atmosphere on Physical and Technological Properties of European Wood Species with Different Structural Features [PDF]

, 2022
P. Kozakiewicz, Agnieszka Laskowska, Michał Drożdżek, J. Zawadzki   +3 more
openalex   +1 more source

Surface modification of HVOF thermal sprayed WC–CoCr coatings by laser treatment [PDF]

, 2010
In this work the affects of laser characteristics on microstructure and microhardness of high velocity oxygen fuel sprayed (HVOF) WC–CoCr coatings were investigated.
A. Forn, AK Maiti, B Wielage, BE Bodger, BS Mann, D. Brabazon, E Cappelli, E. Chikarakara, G Barbezat, IM Hutchings, J Mateos, J. A. Picas, JKN Murthy, M. Punset, P Serra, RJK Wood, S. Aqida, S. Naher, SH Zhang, TY Cho   +19 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Evaluation of different models for validating of photovoltaic cell temperature under semi-arid conditions

Heliyon, 2021
Photovoltaic (PV) solar energy enables direct production of electricity. The photovoltaic effect produced in the solar cells converts light energy from the sun's rays into electricity.
Ibtissam Lamaamar, Amine Tilioua, Zaineb Ben Zaid, Abdelhak Babaoui, Mahmoud Ettakni, Moulay Ahmed Hamdi Alaoui   +5 more
doaj   +1 more source

Quantum corrections to thermodynamics of quasitopological black holes

, 2017
Based on the modification to area-law due to thermal fluctuation at small horizon radius, we investigate the thermodynamics of charged quasitopological and charged rotating quasitopological black holes.
Upadhyay, Sudhaker
core   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Multi-Scale Characterisation of the Fire Hazards of Timber Cladding

Fire
Timber-clad facades, traditionally prevalent in North America and Scandinavia, are gaining popularity in central Europe and the UK for applications beyond low-rise buildings. Timber differs from typical cladding materials, such as masonry, due to its non-
Danny Hopkin, Michael Spearpoint, Yorgos Kanellopoulos, Carmen Gorska, Chris Mayfield   +4 more
doaj   +1 more source