Results 51 to 60 of about 692,380 (296)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Numerical Simulation and Optimized Field-Driven Design of Triple Periodic Minimal Surface Structure Liquid-Cooling Radiator

Energies
This work investigates the design of liquid-cooled heat sinks for IGBT modules via optimizing the Triple Periodic Minimal Surface (TPMS) structure. The performance of heat sinks with different porosity TPMS structures was compared through the finite ...
Zhuopei Lv, Xinbo Chai, Fuyin Wei, Hongkai Yang, Chao Wu, Jianping Shi   +5 more
doaj   +1 more source

A Review on Energy Consumption Optimization Techniques in IoT Based Smart Building Environments [PDF]

, 2019
In recent years, due to the unnecessary wastage of electrical energy in residential buildings, the requirement of energy optimization and user comfort has gained vital importance.
Fayaz, Muhammad, Lajis, Adidah, Nasir, Haidawati, Shah, Abdul Salam, Shah, Asadullah   +4 more
core   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Crystallization of Biogenic Hydroxyapatite: Phase Purity and Morphological Control via Successive Annealing and Grinding

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi
Hydroxyapatite (HAp) derived from biogenic sources offers a sustainable and cost-effective alternative to synthetic materials, yet controlling its crystal structure and morphology remains a key challenge.
H. Esma Okur
doaj   +1 more source

Environment Optimization Scheme Based on Edge Computing Using PSO for Efficient Thermal Comfort Control in Resident Space

Actuators, 2021
With the fast development of infrastructure and communication technology, the Internet of Things (IoT) has become a promising field. Ongoing research is looking at the smart home environment as the most promising sector that adopts IoT and cloud ...
Rongxu Xu, Wenquan Jin, Dohyeun Kim
doaj   +1 more source

On the use of thermal conductive focusing for solar concentration enhancement [PDF]

, 2016
© 2016. This version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/We discuss the possibility for solar concentration enhancement via conductive heat transport. Here, we are concerned, as in orthodox
Arias Montenegro, Francisco Javier
core   +2 more sources

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Topology optimization for near-junction thermal spreading of electronics in ballistic-diffusive regime

iScience, 2023
Summary: Hotspots in electronic devices can cause overheating and reduce performance. Enhancing the thermal spreading ability is critical for reducing device temperature to improve the reliability. However, as devices shrink, phonon ballistic effects can
Zheng-Lai Tang, Yang Shen, Han-Ling Li, Bing-Yang Cao   +3 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source