Results 51 to 60 of about 705,331 (300)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Topology optimization for near-junction thermal spreading of electronics in ballistic-diffusive regime

open access: yesiScience, 2023
Summary: Hotspots in electronic devices can cause overheating and reduce performance. Enhancing the thermal spreading ability is critical for reducing device temperature to improve the reliability. However, as devices shrink, phonon ballistic effects can
Zheng-Lai Tang   +3 more
doaj   +1 more source

Computing complexity measures for quantum states based on exponential families

open access: yes, 2012
Given a multiparticle quantum state, one may ask whether it can be represented as a thermal state of some Hamiltonian with k-particle interactions only.
Galla, Tobias   +3 more
core   +1 more source

A Review on Energy Consumption Optimization Techniques in IoT Based Smart Building Environments [PDF]

open access: yes, 2019
In recent years, due to the unnecessary wastage of electrical energy in residential buildings, the requirement of energy optimization and user comfort has gained vital importance.
Fayaz, Muhammad   +4 more
core   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Multiobjective design optimization of parabolic trough collectors

open access: yesScientific Reports, 2022
Despite the large amount of research conducted on PTC performance analysis, few and rare numbers of research have considered the design optimization of PTCs.
Mohamed Mahran Kasem
doaj   +1 more source

Thermal Energy Optimization of Building Integrated Semi-Transparent Photovoltaic Thermal Systems [PDF]

open access: yes, 2015
Building integrated photovoltaic (BIPV) : The concept where the photovoltaic element assumes the function of power generation and the role of the covering component element has the potential to become one of the principal sources of renewable energy for ...
Agrawal, B. (Basant)   +2 more
core  

A three-stage optimization methodology for envelope design of passive house considering energy demand, thermal comfort and cost [PDF]

open access: yes, 2020
Due to reducing the reliance of buildings on fossil fuels, Passive House (PH) is receiving more and more attention. It is important that integrated optimization of passive performance by considering energy demand, cost and thermal comfort.
Feng, W, Lu, S, Wang, R
core  

Cool Roof Impact on Building Energy Need: The Role of Thermal Insulation with Varying Climate Conditions [PDF]

open access: yes, 2019
Cool roof effectiveness in improving building thermal-energy performance is affected by different variables. In particular, roof insulation level and climate conditions are key parameters influencing cool roofs benefits and whole building energy ...
Cabeza, Luisa F.   +5 more
core   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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