Results 51 to 60 of about 164,686 (263)
Multiobjective design optimization of parabolic trough collectors
Despite the large amount of research conducted on PTC performance analysis, few and rare numbers of research have considered the design optimization of PTCs.
Mohamed Mahran Kasem
doaj +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Optimization-Based Network Identification for Thermal Transient Measurements
Network identification by deconvolution is a proven method for determining the thermal structure function of a given device. The method allows to derive the thermal capacitances as well as the resistances of a one-dimensional thermal path from the ...
Nils J. Ziegeler +2 more
doaj +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Since dye-sensitized solar cells (DSSC) have a suitable efficiency in the invisible region, they present a promising avenue for sustainable energy generation, particularly in the context of indoor environments where ambient lighting prevails.
Mona Rahmatian +2 more
doaj +1 more source
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Radial movement optimization (RMO) technique for solving unit commitment problem in power systems
Unit commitment (UC) is one of the nonlinear optimization problems with linear and nonlinear constraints. In this work, radial movement optimization (RMO) is employed to solve the optimal thermal unit commitment problem. Radial movement optimization is a
Vanithasri M. +2 more
doaj +1 more source
Gradient-based optimization of spacecraft and aircraft thermal design
Steady-case thermal analysis plays an important role in dimensioning thermal control systems for spacecrafts and aircrafts. Usually a trial and error approach is used based on engineering judgement and experience.
Laurynas Mačiulis, Rimantas Belevičius
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Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
OPTIMIZATION OF THERMAL LAYOUT DESIGN OF ELECTRONIC EQUIPMENTS ON THE PRINTED CIRCUIT BOARD
A thermal layout modeling and optimization routine for a Printed Circuit Board (PCB) has been made in the present work. The thermal model includes the modeling of electronic components based on thermal resistances and the PCB as a flat plate with ...
Ihsan Y. Hussain +1 more
doaj +1 more source

