Results 71 to 80 of about 621,425 (316)

Solid-state thermal control devices

open access: yes, 2021
Over the past decade, solid-state thermal control devices have emerged as potential candidates for enhanced thermal management and storage. They distinguish themselves from traditional passive thermal management devices in that their thermal properties ...
Yalamarthy, Ananth   +10 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Effects of Thermal Stress on Dual Task Performance and Attention Allocation

open access: yes, 2005
A visual-visual dual task was designed to test the effect of the thermal environment on dual task performance and attention allocation. The temperatures selected for testing were 20 and 35°C Wet Bulb Globe Temperature (WBGT) in experiment 1 and 25, 30 ...
Waldemar Karwowski   +7 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Thermal performance of radiative cooling panels [PDF]

open access: yesInternational Journal of Heat and Mass Transfer, 1983
Abstract The performance of panels which cool by.means of thermal infrared heat transfer to the sky is calculated from basic principles. The efficiency of a radiative cooling panel is defined. Computer calculations with the full heat transfer equations are performed for horizontal surfaces with infrared-transparent covers.
Berdahl, P., Martin, M., Sakkal, F.
openaire   +2 more sources

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

CFD Analysis of Thermal Performance Enhancement in Ribbed Microchannels Using Nanofluids

open access: yesEntropie
A 2-D numerical investigation was carried out to study the nanofluid flow and heat transfer inside a horizontal ribbed micro-channel. The alumina oxide nanoparticles were suspended in water as based fluid at different volume fraction 0, 2 and 4 ...
Khadija Madani, Rejeb Ben Maad
doaj   +1 more source

Performance of a building integrated photovoltaic/thermal (BIPVT) solar collector

open access: yes, 2009
The idea of combining photovoltaic and solar thermal collectors (PVT collectors) to provide electrical and heat energy is an area that has, until recently, received only limited attention.
Carson, James K.   +3 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

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