Results 61 to 70 of about 1,665,855 (306)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Transfer Learning for Thermal Comfort Prediction in Multiple Cities

, 2020
HVAC (Heating, Ventilation and Air Conditioning) system is an important part of a building, which constitutes up to 40% of building energy usage. The main purpose of HVAC, maintaining appropriate thermal comfort, is crucial for the best utilisation of ...
David, Klaus, Gao, Nan, Rahaman, Mohammad Saiedur, Salim, Flora D., Shao, Wei, Zhai, Jun   +5 more
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Experimental Study on the Factors Influencing the Thermal Performance of Vaccine Refrigeration Vehicles

Zhileng xuebao, 2023
To investigate the temperature distribution and optimize the thermal performance of a vehicle carriage for transporting refrigerated vaccines, a 3.9 m3 vehicle carriage working within the temperature range of 2–8 °C is examined in this study.
Zhao Juan, Zhang Zhongbin, Chen Meng, Gan Qiang, Gong Li, Song Ping, Deng Qingqing   +6 more
doaj  

Thermal effects in InGaAs/AlAsSb quantum-cascade lasers [PDF]

, 2006
A quantum-cascade laser (QCL) thermal model is presented. On the basis of a finite-difference approach, the model is used in conjunction with a self-consistent carrier transport model to calculate the temperature distribution in a near-infrared InGaAs ...
C.A. Evans, D. Indjin, Evans, Evans, Jovanović, P. Harrison, V.D. Jovanović, Yang, Yang, Yu, Yu, Z. Ikonić, Zhang   +12 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Menstrual Health in Servicewomen: The Menstrual Cycle, Menstrual Disturbances, and Occupational Consequences

Sports Medicine - Open
Background Most women serving in the military do so during their reproductive life and enter service at a young gynecological age. This review provides an overview of the menstrual cycle and summarizes the evidence for menstrual cycle disturbances in the
Ritva S. Mikkonen, Holly McClung, Gabrielle Giersch, Jeroen Van Cutsem, Helen Wright, Thomas J. O’Leary, Julie P. Greeves   +6 more
doaj   +1 more source

Analysing the Effect of Substrate Properties on Building Envelope Thermal Performance in Various Climates

Energies, 2020
Existing regulations on the thermal efficiency of building envelope assemblies are based on the steady state thermal properties of substrate materials.
Kishor T. Zingre, Kiran Kumar D. E. V. S., Man Pun Wan   +2 more
doaj   +1 more source

Invited Article: CO_2 laser production of fused silica fibers for use in interferometric gravitational wave detector mirror suspensions [PDF]

, 2011
In 2000 the first mirror suspensions to use a quasi-monolithic final stage were installed at the GEO600 detector site outside Hannover, pioneering the use of fused silica suspension fibers in long baseline interferometric detectors to reduce suspension ...
Barton, M. A., Bell, A., Cagnoli, G., Cantley, C. A., Crooks, D. R. M., Cumming, A., Grant, A., Hammond, G. D., Harry, G. M., Heptonstall, A., Hough, J., Jones, R., Kelley, D., Kumar, R., Martin, I. W., Robertson, N. A., Rowan, S., Strain, K. A., Tokmakov, K., van Veggel, M.   +19 more
core   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source