Results 61 to 70 of about 621,425 (316)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Experimental Study on the Factors Influencing the Thermal Performance of Vaccine Refrigeration Vehicles

Zhileng xuebao, 2023
To investigate the temperature distribution and optimize the thermal performance of a vehicle carriage for transporting refrigerated vaccines, a 3.9 m3 vehicle carriage working within the temperature range of 2–8 °C is examined in this study.
Zhao Juan, Zhang Zhongbin, Chen Meng, Gan Qiang, Gong Li, Song Ping, Deng Qingqing   +6 more
doaj  

The role of a building’s thermal properties on pupils’ thermal comfort in junior school classrooms as determined in field studies [PDF]

, 2014
Recent thermal comfort research in a light-weight junior school building showed that children were more sensitive to higher temperatures than adults and subsequently that current thermal comfort standards were not appropriate for the assessment of their ...
James, Patrick A.B., Jentsch, Mark F., Teli, Despoina,, James, P.A.B., Teli, Despoina, Jentsch, M.F.   +5 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Menstrual Health in Servicewomen: The Menstrual Cycle, Menstrual Disturbances, and Occupational Consequences

Sports Medicine - Open
Background Most women serving in the military do so during their reproductive life and enter service at a young gynecological age. This review provides an overview of the menstrual cycle and summarizes the evidence for menstrual cycle disturbances in the
Ritva S. Mikkonen, Holly McClung, Gabrielle Giersch, Jeroen Van Cutsem, Helen Wright, Thomas J. O’Leary, Julie P. Greeves   +6 more
doaj   +1 more source

Analysing the Effect of Substrate Properties on Building Envelope Thermal Performance in Various Climates

Energies, 2020
Existing regulations on the thermal efficiency of building envelope assemblies are based on the steady state thermal properties of substrate materials.
Kishor T. Zingre, Kiran Kumar D. E. V. S., Man Pun Wan   +2 more
doaj   +1 more source

Review of Molten-Salt Thermocline Tank Modeling for Solar Thermal Energy Storage

, 2013
Molten-salt thermocline tanks are a low-cost option for thermal energy storage in concentrating solar power systems. A review of previous experimental and numerical thermocline tank studies is performed to identify key issues associated with tank design ...
Yang, Z., Garimella, S V, Flueckiger, S. M.   +2 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Asymmetrical compound parabolic concentrator with single flow system: field-test scale, thermal performance parameters, and E. coli inactivation

Materials Research Express, 2019
This work presents a developed field-test scaled asymmetrical compound parabolic concentrator (ACPC) and an investigation of its performance with a single flow system of water on Escherichia coli inactivation. As a function of water flow rate, ability to
Wreerat Laithong, Phattarathicha Tepsri, Sirichai Thepa, Roongrojana Songprakorp, Sorachon Yoriya   +4 more
doaj   +1 more source

A comparative study of thermal performances of three mud dwelling units with courtyards in composite climate

Journal of Architecture and Urbanism, 2017
Jharkhand is a state in the eastern part of India. The tropic of Cancer (23 and a half degree north line) passes through Ranchi district in Jharkhand. Mud huts with burnt clay tiled roofs in Ranchi district in Jharkhand are an integral component of the ...
Janmejoy Gupta, Manjari Chakraborty, Arnab Paul, Vamsi Korrapatti   +3 more
doaj   +1 more source