Results 171 to 180 of about 37,151 (264)

Deep Learning‐Driven Computational Imaging for Noninvasive Monitoring System of Brain Temperature and Metabolism: A Hypothermia Validation for Acute Ischemic Stroke

MedComm, Volume 7, Issue 8, August 2026.
This study presents the first proof‐of‐concept framework for 3D brain temperature and metabolism imaging using deep learning and clinical validation. An integrated multimodal instrument enables noninvasive neuro‐monitoring, while MRI‐based 3D modeling and computational imaging improve prediction accuracy, visualization quality, and spatial resolution ...
Tianhang Yang, Qihan Zhang, Yilun Huang, Yuan Wang, Fuzhi Cao, Xin Zhang, Ming Wei, Qingfeng Ma, Hongzhi Kuai, Ming Li, Jianzhuo Yan, Miaowen Jiang, Xunming Ji   +12 more
wiley   +1 more source

Innate immune signalling in the adipocyte. [PDF]

J Biochem
Dumesic PA.
europepmc   +1 more source

SIRT Family: Biological Functions and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang, Feng‐Li Jiang, Fang‐Yuan Zhang, Dong‐Hui Huang, Xiao‐Ying Li, Song Gao, Hua You, Qi‐Jun Wu, Huan‐Huan Chen, Ting‐Ting Gong   +9 more
wiley   +1 more source

Cross-Talk Between Signaling and Transcriptional Networks Regulating Thermogenesis-Insights into Canonical and Non-Canonical Regulatory Pathways. [PDF]

Int J Mol Sci
Simka-Lampa K.
europepmc   +1 more source

Metabolic Regulation of Macrophages in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Extracellular metabolites drive metabolic rewiring of glucose, lipid, and amino acid pathways in macrophages, steering their polarization toward pro‐ or anti‐inflammatory phenotypes and shaping a wide range of disease processes. Macrophages from different tissues display distinct metabolic signatures, and therapeutic strategies that target these ...
Shan Huang, Yu Zhang, Jiali Min, Jiahui Yang, Yuchen Li, Hao Zhang, Shanshan Liu   +6 more
wiley   +1 more source

Thermogenic adipose tissue in older adults with obesity: a narrative review of mechanisms, brown fat resistance, and the translational relevance of exercise and nutrition. [PDF]

Front Nutr
Wang F, Qiao H, Zhou H, Zheng Y, Ni Y, He X.   +5 more
europepmc   +1 more source

The Dietary Protein Source Modulates Obesity Development and Induces Distinct Plasma Lipid Profiles and Transcriptome Profiles in Liver and Adipose Tissue

Molecular Nutrition &Food Research, Volume 70, Issue 15, 17 August 2026.
By performing plasma metabolomics analyses combined with RNA sequencing and gene set enrichment analyses of liver, muscle, white‐ and brown‐adipose tissue in mice, we aimed to decipher the metabolic output and pathways modulated by intake of different dietary proteins.
Lene S. Myrmel, Even Fjære, Annette Bernhard, Josef D. Rasinger, Ole Jakob Nøstbakken, Helene Søiland, Philipp Rausch, Martin von Bergen, Ulrike Rolle‐Kampzcyk, Liang Xiao, Hanlin Zhou, Guibo Li, Karsten Kristiansen, Lise Madsen   +13 more
wiley   +1 more source

Deciphering Uncoupling Proteins in Cellular Homeostasis and Metabolic Health. [PDF]

Int J Biol Sci
Liu YT, Ding YJ, Qiu HL, Che Y, Tang QZ.
europepmc   +1 more source

Dietary Titanium Dioxide (E171) Alters the Colon Transcriptome—Evidence From a Human Dietary Intervention Study

Molecular Nutrition &Food Research, Volume 70, Issue 16, 27 August 2026.
Oral E171 exposure (2 mg/kg body weight/day) in a randomized cross‐over study of 31 healthy adults increased fecal titanium and blood superoxide while altering the colon transcriptome and enriching 73 pathways linked to oxidative stress, metabolism, and colorectal cancer.
Nicolaj S. Bischoff, Anna K. Undas, Greet van Bemmel, Marcel van Herwijnen, Marcha Verheijen, Simone G. Van Breda, Jacco J. Briedé, Lana Drenth‐Brink, Marcella Peelen‐Buijs, Iris Elferink, Héloïse Proquin, Henk van Loveren, Ad A. van Bodegraven, Dick T. H. M. Sijm, Theo M. de Kok   +14 more
wiley   +1 more source

Fueling or Fighting Cancer? The Thermogenic Paradox of Brown Adipose Tissue. [PDF]

Curr Obes Rep
Guerrero JJG, Encarnacion PC, Wang CH, Del Rosario MAS, Notarte KI, Zhou J, Hsieh YT, Wang WY, Chang CW, Li WC.   +9 more
europepmc   +1 more source