Results 81 to 90 of about 49,629 (277)
ABSTRACT Triple‐negative breast cancer (TNBC) represents the most aggressive subtype with limited therapeutic options and the poorest clinical outcomes. Using high‐resolution nUPLC‐QTOF‐MS/MS, we performed comprehensive proteomic profiling of TNBC cell lines representing disease progression stages: HCC‐1937 (stage IIB), HCC‐1599 (stage IIIA), and MDA ...
Claudia Sissely Chaviano‐Montes de Oca +7 more
wiley +1 more source
ABSTRACT Obesity is a major risk factor for type 2 diabetes. Some traditional Chinese medicine (TCM) compounds can improve obesity by increasing energy consumption. This study aimed to identify and verify TCM compounds that promote adipose thermogenesis to alleviate obesity via transcriptomic analysis, molecular docking, network pharmacology, and ...
Jing Li +6 more
wiley +1 more source
Microcalorimetric studies on the thermogenesis of energy release of mitochondria isolated from rice
After isolation from rice mitochondria still have activity and can live for a long time by using its stored nutrients. The thermogenesis curves of energy release of the mitochondria isolated from variant strains of rice have been determined by using an ...
Han-Tao Zhou +7 more
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Non-Shivering Thermogenesis in Birds: A Role for Skeletal Muscle
Avian non-shivering thermogenesis (NST) is still a controversial topic. Empirical data collected in the past two decades have demonstrated that NST is potentially one of the mechanisms deployed by birds to modulate their thermoregulation.
Bicudo, José Eduardo Pereira Wilken +2 more
core +1 more source
Intuitively, an animal that is able to produce more heat internally (e.g. through BAT-thermogenesis) could tolerate having a greater exposed surface area.
Roderich Groß (791841) +3 more
core +1 more source
Salvia miltiorrhiza Bunge in metabolic syndrome and cardiovascular diseases: multi‐target actions on shared signaling pathways. ABSTRACT Metabolic syndrome (MetS) represents a clinical disorder characterized by the clustering of conditions including obesity, elevated blood sugar levels, and high lipid levels, which are intricately linked to the onset ...
Zhiyi Jia +6 more
wiley +1 more source
Hyperoside ameliorates metabolic dysfunction in high‐fat diet‐induced type 2 diabetic mice, accompanied by enhanced brown adipose tissue thermogenic activity, inguinal white adipose tissue browning‐related changes, reduced M1 macrophage polarization, and gut microbiota remodeling.
WeiFeng Cai +7 more
wiley +1 more source
Mogroside V Promotes Brown Adipose Thermogenesis via FTO‐m6A‐LETMD1‐UCP1 Pathway to Combat Obesity
Mogroside V (MV) alleviates high‐fat diet‐induced obesity and metabolic dysfunction. Mechanistically, MV suppresses FTO expression, thereby increasing m6A modification of Letmd1 mRNA and enhancing its YTHDC2‐dependent stabilization. Theincreased LETMD1 expression is associated with elevated PGC1α and UCP1 levels, contributing to brown adipocyte ...
Yuan‐hai Sun +5 more
wiley +1 more source
ABSTRACT Microplastics (MPs) have been identified as major environmental contaminants that can affect organisms directly and act as carriers of particles and chemical additives, thereby aggravating endocrine networks that coordinate metabolic homeostasis.
Sunday Amos Onikanni +10 more
wiley +1 more source
Thermogenesis and Deacclimatization in Mice Raised at High Altitud [PDF]
:T he male mice were raised in the tent of Yatsugatake laboratory (2,400m above the sea leve ,)l YG, for about one month from October to November in 1986 and in the laboratory of matsumoto (6 10m above the sea le ,v)le MG. The average ambient temperature
上田, 五雨 +7 more
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