Beyond Pleasure: Unraveling the Multifaceted Role of Dopamine in Obesity and Metabolic Regulation. [PDF]
Yang S +9 more
europepmc +1 more source
Migrating songbirds regularly use shallow torpor (up to 98% of birds for some species) to save energy (up to 42%) during inactive periods. This Ruby‐crowned Kinglet Corthylio calendula that was captured after a spring snowstorm highlights the value of being able to save energy when encountering unfavourable conditions.
Ryan A. C. Leys +2 more
wiley +1 more source
Exercise and cold exposure as dual physiological stressors in MASLD: AMPK-mediated metabolic adaptation and interorgan crosstalk. [PDF]
Wang S, Gao Y, Wang Y, Wang J, Liu Y.
europepmc +1 more source
ABSTRACT Background Adequate nutrition during pregnancy is well established; however, how pregnancy affects energy metabolism, particularly the relationship between energy intake, expenditure and maternal mass, remains poorly understood. Current dietary recommendations advise increasing energy intake across pregnancy, but these are based on theoretical
Georgia S. Clarke +3 more
wiley +1 more source
ATP Release and Purinergic Signaling Potentiate β‐Adrenergic Effects on Brown Adipocytes
ABSTRACT Aim Brown adipose tissue (BAT) specializes in energy consumption and thermogenesis in response to cold stress. Brown adipocytes (BA) express purinergic receptors, yet little is known about the source of extracellular ATP and the role of purinergic signaling, and the potential interaction with β‐adrenergic signaling.
Marco Tozzi +8 more
wiley +1 more source
Cox10-mediated mitochondrial respiration in brown adipocytes regulates adaptive thermogenesis and systemic metabolism. [PDF]
Paulo E, Wu Y, Wang B.
europepmc +1 more source
IMPROVE 2025: The 3rd International Meeting on Pathway‐Related Obesity: Vision & Evidence
ABSTRACT An international cohort of 161 clinicians and researchers from 19 countries attended the 3rd International Meeting on Pathway‐Related Obesity: Vision & Evidence (IMPROVE) in Prague, Czech Republic, on 2–4 July 2025. The aims of the meeting were to advance understanding of hyperphagia and obesity caused by defects in the melanocortin‐4 receptor
Jesús Argente +17 more
wiley +1 more source
Junctophilin-2-orchestrated calcium signalosome regulates brown adipocyte thermogenesis and energy metabolism. [PDF]
Chen B +23 more
europepmc +1 more source
Life‐stage variation in Sable Shearwater (Ardenna carneipes) physiology assessed using proteomics
Life‐stage transitions in seabirds involve substantial shifts in physiological demands, yet the molecular mechanisms underpinning these changes remain poorly resolved. Here we applied untargeted data‐independent acquisition mass spectrometry (DIA‐MS) to characterize and compare the plasma proteomes of fledgling and adult Sable Shearwaters Ardenna ...
Alix M. de Jersey +5 more
wiley +1 more source
Cold Exposure Shifts Gut Microbial Butyrate Synthesis Toward the Lysine-Dependent and But-Mediated Terminal Pathways to Enhance Cold Tolerance in Min Pigs. [PDF]
Chang Y +8 more
europepmc +1 more source

