Results 81 to 90 of about 45,442 (301)
Advanced Science, 2023 Recent genetic evidence has linked WNT downstream mutations to fat distribution. However, the roles of WNTs in human obesity remain unclear. Here, the authors screen all Wnt‐related paracrine factors in 1994 obese cases and 2161 controls using whole ...
Yingkai Sun +19 more
doaj +1 more source
The Liver as a Hub in Thermogenesis [PDF]
Cell Metabolism, 2017 Manipulating thermogenesis could increase energy expenditure and improve metabolism. Brown fat is a major site of nonshivering thermogenesis, but other tissues, notably muscle and liver, can contribute to cold adaptation. In this issue, Simcox et al.
openaire +2 more sources
Real‐time biosensing of Parkinson's disease biomarkers via NIR‐activated upconversion nanoparticles
BMEMat, EarlyView.Schematic illustration of the luminescence resonance energy transfer‐driven core‐shell‐shell UCNPs (cssUCNPs@Fluo4) nanoprobe for simultaneous monitoring of Ca²⁺‐temperature dynamics in Parkinson's disease models. Abstract Parkinson's disease (PD) is a progressive neurodegenerative disorder with incompletely understood pathophysiology, necessitating ...
Jialin Liu +9 more
wiley +1 more source
Frontiers in NutritionThe development of strategies that promote the activation of adaptive thermogenesis in brown and beige adipose tissues is expected to lead to advances in the prevention and treatment of obesity, diabetes, and cardiovascular diseases.
Bruna Bombassaro +7 more
doaj +1 more source
Cold exposure induces lipid dynamics and thermogenesis in brown adipose tissue of goats
BMC Genomics, 2022 Background Adaptive thermogenesis by brown adipose tissue (BAT) is important to the maintenance of temperature in newborn mammals. Cold exposure activates gene expression and lipid metabolism to provide energy for BAT thermogenesis. However, knowledge of
Xin Liu +10 more
doaj +1 more source
Thermogenesis in Adipose Tissue Activated by Thyroid Hormone [PDF]
, 2020 Thermogenesis is the production of heat that occurs in all warm-blooded animals. During cold exposure, there is obligatory thermogenesis derived from body metabolism as well as adaptive thermogenesis through shivering and non-shivering mechanisms.
Winifred W. Yau, Paul M. Yen
core +1 more source
Food Safety and Health, EarlyView.Circadian rhythm disruption impairs metabolic regulation, appetite control, and vascular function, promoting obesity and cardiovascular diseases. Evidence highlights a bidirectional relationship where metabolic disorders further disturb circadian timing.
Ghizal Fatima +4 more
wiley +1 more source
A brown fat-enriched adipokine Adissp controls adipose thermogenesis and glucose homeostasis
Nature Communications, 2022 The signaling mechanisms regulating adipose thermogenesis have not been fully elucidated. Here, the authors show that a brown fat-enriched adipokine ADISSP promotes adipose thermogenesis and improves metabolic health independently of b-adrenergic ...
Qingbo Chen +9 more
doaj +1 more source
α2 adrenergic receptor-mediated inhibition of thermogenesis [PDF]
, 2013 2 adrenergic receptor ( 2-AR) agonists have been used as antihypertensive agents, in the management of drug withdrawal, and as sedative analgesics. Since 2-AR agonists also influence the regulation of body temperature, we explored their potential as ...
Morrison, Shaun F. +3 more
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BiomoleculesAllostatic adaptations to a perceived threat are crucial for survival and may tap into mechanisms serving the homeostatic control of energy balance. We previously established that exposure to predator odor (PO) in rats significantly increases skeletal ...
Christina A. Watts +7 more
doaj +1 more source