Results 171 to 180 of about 65,191 (322)

Impact of acute caffeine intake on local tolerance to cold before and after total sleep deprivation

open access: yesExperimental Physiology, EarlyView.
Abstract Total sleep deprivation (TSD) alters local cold tolerance and could thus increase the risk of cold injury. We evaluated the impact of acute caffeine intake, the main countermeasure to TSD‐related deleterious effects, on local cold tolerance before and after TSD.
Baptiste de Lorgeril   +11 more
wiley   +1 more source

Association between thyroid function and acute mountain sickness upon rapid ascent to 3650 m in euthyroid lowlanders in China

open access: yesExperimental Physiology, EarlyView.
This study evaluated the association between baseline thyroid hormones levels, sensitivity index and the incidence of AMS in 70 healthy individuals traveling from Beijing (44 m above sea level) to Lhasa (3650 m above sea level). The dataset was divided into a training set (n = 56) and a validation set (n = 14) at an ratio of 8:2.
Cencen Wu   +13 more
wiley   +1 more source

Lipolysis sensation by white fat afferent nerves triggers brown fat thermogenesis

open access: yesMolecular Metabolism, 2016
Objective: Metabolic challenges, such as a cold environment, stimulate sympathetic neural efferent activity to white adipose tissue (WAT) to drive lipolysis, thereby increasing the availability of free fatty acids as one source of fuel for brown adipose ...
John T. Garretson   +5 more
doaj  

Acclimatization to cold in humans [PDF]

open access: yes
This review focuses on the responses and mechanisms of both natural and artificial acclimatization to a cold environment in mammals, with specific reference to human beings.
Greenleaf, John E.   +1 more
core   +1 more source

Topical application of the cold‐mimetic l‐menthol decreases wheel running without affecting the beneficial effects of voluntary exercise in mice

open access: yesExperimental Physiology, EarlyView.
Abstract Topical application of l‐menthol, a pharmacological cold‐mimetic and agonist of the cold‐sensing receptor TRPM8 (transient receptor potential cation channel subfamily M member 8), has been shown to stimulate brown adipose tissue (BAT) thermogenesis and reduce weight gain in both obese and lean male mice, without affecting energy intake.
Annalaura Bellucci   +8 more
wiley   +1 more source

Oxyntomodulin physiology and its therapeutic development in obesity and associated complications

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Physiological influences of OXM and its emerging insights from evidence on bariatric surgery effects. CCK, cholecystokinin; FGF21, fibroblast growth factor 21; GLUT4, glucose transporter type 4; IRS1, insulin receptor substrate‐1; NNMT, nicotinamide N‐methyltransferase; OXM, oxyntomodulin Abstract Incretins, such as glucagon‐like
Martin T. W. Kueh   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy