Transfer RNA methyltransferases from Thermoplasma acidophilum, a thermoacidophilic archaeon. [PDF]
Int J Mol Sci, 2014 We investigated tRNA methyltransferase activities in crude cell extracts from the thermoacidophilic archaeon Thermoplasma acidophilum. We analyzed the modified nucleosides in native initiator and elongator tRNAMet, predicted the candidate genes for the ...
Kawamura T +4 more
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Structure and Stability of the Dimeric Triosephosphate Isomerase from the Thermophilic Archaeon Thermoplasma acidophilum. [PDF]
PLoS ONE, 2015 Thermoplasma acidophilum is a thermophilic archaeon that uses both non-phosphorylative Entner-Doudoroff (ED) pathway and Embden-Meyerhof-Parnas (EMP) pathway for glucose degradation.
Sang Ho Park +10 more
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Crystal structure of (S)-3-O-geranylgeranylglyceryl phosphate synthase from Thermoplasma acidophilum in complex with the substrate sn-glycerol 1-phosphate. [PDF]
Acta Crystallogr F Struct Biol Commun, 2019 (S)-3-O-Geranylgeranylglyceryl phosphate synthase (GGGPS) catalyzes the initial ether-bond formation between sn-glycerol 1-phosphate (G1P) and geranylgeranyl pyrophosphate to synthesize (S)-3-O-geranylgeranylglyceryl phosphate in the production of an ...
Nemoto N +3 more
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The RecJ2 protein in the thermophilic archaeon Thermoplasma acidophilum is a 3'-5' exonuclease that associates with a DNA replication complex. [PDF]
J Biol Chem, 2017 RecJ/cell division cycle 45 (Cdc45) proteins are widely conserved in the three domains of life, i.e. in bacteria, Eukarya, and Archaea. Bacterial RecJ is a 5′-3′ exonuclease and functions in DNA repair pathways by using its 5′-3′ exonuclease activity ...
Ogino H, Ishino S, Kohda D, Ishino Y.
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BiomoleculesThe exosome multiprotein complex plays a critical role in RNA processing and degradation. This system governs the regulation of mRNA quality, degradation in the cytoplasm, the processing of short noncoding RNA, and the breakdown of RNA fragments.
Seonha Park +7 more
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Multisite-specific archaeosine tRNA-guanine transglycosylase (ArcTGT) from Thermoplasma acidophilum, a thermo-acidophilic archaeon. [PDF]
Nucleic Acids Res, 2016 Archaeosine (G+), which is found only at position 15 in many archaeal tRNA, is formed by two steps, the replacement of the guanine base with preQ0 by archaeosine tRNA-guanine transglycosylase (ArcTGT) and the subsequent modification of preQ0 to G+ by ...
Kawamura T +7 more
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(R)-mevalonate 3-phosphate is an intermediate of the mevalonate pathway in Thermoplasma acidophilum. [PDF]
J Biol Chem, 2014 Background: A few enzyme reactions in the mevalonate pathway remain unclear in most archaea. Results: (R)-Mevalonate 3-phosphate is synthesized by Ta1305 protein from Thermoplasma acidophilum and is converted into isopentenyl diphosphate in cell-free ...
Azami Y +5 more
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Occupancy of the HbYX hydrophobic pocket is sufficient to induce gate opening in the archaeal 20S proteasomes [PDF]
eLifeEnhancing proteasome function has been a long-standing but challenging target of interest for the potential treatment of neurodegenerative diseases, emphasizing the importance of understanding proteasome activation mechanisms.
Janelle JY Chuah +2 more
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An active site-tail interaction in the structure of hexahistidine-tagged Thermoplasma acidophilum citrate synthase. [PDF]
Acta Crystallogr F Struct Biol Commun, 2015 Citrate synthase from the thermophilic euryarchaeon T. acidophilum fused to a hexahistidine tag was purified and biochemically characterized. The structure of the unliganded enzyme at 2.2 Å resolution contains tail–active site contacts in half of the ...
Murphy JR, Donini S, Kappock TJ.
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A new crystal form of the DNA-free full-length XPD helicase from Thermoplasma acidophilum. [PDF]
Acta Crystallogr F Struct Biol CommunBravo M, Fan L.
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