Results 121 to 130 of about 2,155 (226)

TRP ion channels in thermosensation, thermoregulation and metabolism [PDF]

Temperature, 2015
In humans, the TRP superfamily of cation channels includes 27 related molecules that respond to a remarkable variety of chemical and physical stimuli. While physiological roles for many TRP channels remain unknown, over the past years several have been shown to function as molecular sensors in organisms ranging from yeast to humans.
Hong Wang, Jan Siemens
openaire   +2 more sources

TRP Channels Entering the Structural Era [PDF]

, 2013
Transient receptor potential (TRP) channels are important in many neuronal and non-neuronal physiological processes. The past 2 years have seen much progress in the use of structural biology techniques to elucidate molecular mechanisms of TRP channel ...
Gaudet, Rachelle
core   +1 more source

Complex plant responses to drought and heat stress under climate change

The Plant Journal, Volume 117, Issue 6, Page 1873-1892, March 2024.
Significance Statement In this review, we explain how plants respond to drought, heat, and their combined stress at both physiological and molecular levels. Additionally, we summarize novel resilience mechanisms revealed through natural variations and discuss strategies for developing crops resilient to the increasing dry and hot conditions resulting ...
Hikaru Sato, Junya Mizoi, Kazuo Shinozaki, Kazuko Yamaguchi‐Shinozaki   +3 more
wiley   +1 more source

Intrinsic Thermal Sensing Controls Proteolysis of Yersinia Virulence Regulator RovA [PDF]

, 2009
Pathogens, which alternate between environmental reservoirs and a mammalian host, frequently use thermal sensing devices to adjust virulence gene expression. Here, we identify the Yersinia virulence regulator RovA as a protein thermometer. Thermal shifts
A Lupas, AK Heroven, AK Heroven, AK Heroven, AK Heroven, AL Goldberg, Ann Kathrin Heroven, Ariane Zimmermann, DA Parsell, DW Ellison, DW Ellison, E Gur, EJ Bottone, G Nagel, G Zhao, HC Huang, HJ Koornhof, HJ Tran, I Bolin, I Lee, IM Shah, IM Shah, JM Flynn, JR Rohde, JS Cathelyn, K Nomura, KA Datsenko, Katharina Herbst, KC Keiler, KH Wang, L Wang, M Gonzalez, M Marceau, M Pruteanu, Martin Weichert, Matthias Bujara, MB Lawrenz, ME Konkel, MW Jackson, NC Stenseth, NP Hoe, NR Thomson, O Gal-Mor, P Legault, P Servant, PA Revell, Petra Dersch, R Hurme, Ralph R. Isberg, RT Sauer, S Gottesman, S Licht, SC Straley, SG Rudyak, SP Wilkinson, TA Baker, TA Phillips, V Tsilibaris, VL Motin, W Schumann, Wiebke Opitz   +60 more
core   +4 more sources

A Precise Temperature-Responsive Bistable Switch Controlling Yersinia Virulence.

PLoS Pathogens, 2016
Different biomolecules have been identified in bacterial pathogens that sense changes in temperature and trigger expression of virulence programs upon host entry.
Aaron Mischa Nuss, Franziska Schuster, Louisa Roselius, Johannes Klein, René Bücker, Katharina Herbst, Ann Kathrin Heroven, Fabio Pisano, Christoph Wittmann, Richard Münch, Johannes Müller, Dieter Jahn, Petra Dersch   +12 more
doaj   +1 more source

Allosteric Activation of Bacterial Response Regulators: the Role of the Cognate Histidine Kinase Beyond Phosphorylation [PDF]

, 2014
Response regulators are proteins that undergo transient phosphorylation, connecting specific signals to adaptive responses. Remarkably, the molecular mechanism of response regulator activation remains elusive, largely because of the scarcity of ...
Aguilar, Pablo Sebastián, Albanesi, Daniela, Botti, Horacio, Buschiazzo, Alejandro, Cybulski, Larisa Estefania, de Mendoza, Diego, Larrieux, Nicole, Mechaly, Ariel, Nieves, Marcos, Ruetalo, Natalia, Trajtenberg, Felipe   +10 more
core   +4 more sources

Stabilizing a mammalian RNA thermometer confers neuroprotection in subarachnoid hemorrhage

Nature Communications
Mammals tightly regulate their core body temperature, yet how cells sense and respond to small temperature changes remains incompletely understood.
Min Zhang, Bin Zhang, Chengli Liu, Marco Preußner, Megha Ayachit, Weiming Li, Yafei Huang, Deyi Liu, Quanwei He, Ann-Kathrin Emmerichs, Stefan Meinke, Shu Chen, Lin Wang, Liduan Zheng, Qiubai Li, Qin Huang, Tom Haltenhof, Ruoxi Gao, Xianan Qin, Aifang Cheng, Tianzi Wei, Li Yu, Mario Schubert, Xin Gao, Mingchang Li, Florian Heyd   +25 more
doaj   +1 more source

Temperature regulation of plant hormone signaling during stress and development [PDF]

, 2021
Global climate change has broad-ranging impacts on the natural environment and human civilization. Increasing average temperatures along with more frequent heat waves collectively have negative effects on cultivated crops in agricultural sectors and wild
Castroverde, Christian, Dina, Damaris
core   +1 more source

Thermosensation: Hot Findings Make TRPNs Very Cool [PDF]

Current Biology, 2003
TRPV and TRPM proteins have been shown to form temperature-responsive cation channels that act in nociception. Recent work on the mouse ANKTM1 and Drosophila Painless proteins shows that members of a third TRP subfamily, TRPN, also function in thermosensation.
openaire   +2 more sources

cGMP dynamics underlie thermosensation in C. elegans [PDF]

, 2019
AbstractAnimals sense ambient temperature so that they can adjust their behavior to the environment; they avoid noxious heat and coldness and stay within a survivable temperature range. C. elegans can sense temperature, memorize past cultivation temperature and navigate towards preferable temperature, for which a thermosensory neuron, AFD, is essential.
Aoki, Ichiro, Shiota, Makoto, Nakano, Shunji, Mori, Ikue   +3 more
openaire   +1 more source