Results 51 to 60 of about 1,938 (214)
eLife, 2016 Venom toxins are invaluable tools for exploring the structure and mechanisms of ion channels. Here, we solve the structure of double-knot toxin (DkTx), a tarantula toxin that activates the heat-activated TRPV1 channel. We also provide improved structures
Chanhyung Bae +10 more
doaj +1 more source
RNA thermosensors facilitate Streptococcus pneumoniae and Haemophilus influenzae immune evasion.
PLoS Pathogens, 2021 Bacterial meningitis is a major cause of death and disability in children worldwide. Two human restricted respiratory pathogens, Streptococcus pneumoniae and Haemophilus influenzae, are the major causative agents of bacterial meningitis, attributing to ...
Hannes Eichner +6 more
doaj +1 more source
Gene Regulatory Changes Associated With Phenological Transitions in an Ecologically Significant Tree Species. [PDF]
Plant Environ InteractClimate change is driving earlier spring leaf‐out across temperate regions, but the genetic mechanisms and environmental interactions underlying this variability are poorly understood. We conducted a controlled growth chamber experiment using excised northern red oak (Quercus rubra) branches, testing the influence of temperature and photoperiod on leaf
Caso-McHugh T +3 more
europepmc +2 more sources
Fluorescence Turns on‐off‐on Sensing of Ferric Ion and L‐Ascorbic Acid by Carbon Quantum Dots
Journal of Food Quality, Volume 2023, Issue 1, 2023., 2023 This study used a hydrothermal approach to create a sensitive and focused nanoprobe. Using an “on‐off‐on” sensing mechanism, the nanoprobe was employed to detect and quantify ferric ions and L‐ascorbic acid. Synthesis of the carbon quantum dots was achieved with a single hydrothermal step at 180°C for 24 hours using hot pepper as the starting material.
Ravin K. Msto +7 more
wiley +1 more source
Injury Threshold of Oral Contact with Hot Foods and Method for Its Sensory Evaluation
Safety, 2018 Epidemiological studies indicate an increased risk of esophageal cancer from the consumption of very hot foods and beverages. The contact time and the contact temperature are decisive for the risk of injury.
Dirk W. Lachenmeier, Walter Lachenmeier
doaj +1 more source
Temperature Sensing in Plants: On the Dawn of Molecular Thermosensor Research [PDF]
, 2022 text学術雑誌論文 / Journal ArticleAlthough many studies on plant growth and development focus on the effects of light, a growing number of studies dissect plant responses to temperature and the underlying signaling pathways. The identity of plant thermosensing
21903 +3 more
core +1 more source
TREKing noxious thermosensation [PDF]
The EMBO Journal, 2009 The ability to sense environmental temperature as pleasant or unpleasant is associated with the activity of thermo‐sensitive neurons in the peripheral nervous system. Differential sensation of pleasant environmental temperatures (warm and cool) versus unpleasant and noxious (cold and hot) temperatures requires the definition of thresholds and ...
openaire +2 more sources
TRPV3 in skin thermosensation and temperature responses. [PDF]
J Physiol SciHuman skin, as a sophisticated sensory organ, is able to detect subtle changes in ambient temperature. This thermosensory capability is primarily mediated by temperature-sensitive TRP channels expressed in both sensory neurons and keratinocytes. Among these, TRPV3, which responds to warm temperatures and plays a crucial role in various skin functions ...
Lei J, Tominaga M.
europepmc +3 more sources
Molecular Processes in Biological Thermosensation [PDF]
Journal of Biophysics, 2008 Since thermal gradients are almost everywhere, thermosensation could represent one of the oldest sensory transduction processes that evolved in organisms. There are many examples of temperature changes affecting the physiology of living cells. Almost all classes of biological macromolecules in a cell (nucleic acids, lipids, proteins) can present a ...
Digel, Ilya (Prof. Dr.) +2 more
openaire +2 more sources
The Cellular Code for Mammalian Thermosensation [PDF]
The Journal of Neuroscience, 2013 Mammalian somatosenory neurons respond to thermal stimuli and allow animals to reliably discriminate hot from cold and to select their preferred environments. Previously, we generated mice that are completely insensitive to temperatures from noxious cold to painful heat (−5 to 55°C) by ablating several different classes of nociceptor early in ...
Leah A, Pogorzala +2 more
openaire +2 more sources