Results 51 to 60 of about 89,627 (264)
Frontiers in Neuroscience, 2021 This study aimed to examine whether the cortical processing of emotional faces is modulated by the computerization of face stimuli (”avatars”) in a group of 25 healthy participants.
Teresa Sollfrank +14 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Prefrontal-Hippocampal Pathways Through the Nucleus Reuniens Are Functionally Biased by Brain State
Frontiers in Neuroanatomy, 2022 Circuit-level communication between disparate brain regions is fundamental for the complexities of the central nervous system operation. Co-ordinated bouts of rhythmic activity between the prefrontal cortex (PFC) and hippocampus (HPC), in particular, are
Brandon E. Hauer +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Canadian Journal of Gastroenterology and HepatologyBackground. Data on the economic burden of chronic hepatitis C (CHC) among immigrants are limited. Our objective was to estimate the CHC-attributable mortality and healthcare costs among immigrants in Ontario, Canada. Methods.
Aysegul Erman +8 more
doaj +1 more source
Refinements to Mumford’s theta and adelic theta groups [PDF]
Annales mathématiques du Québec, 2014 Let $X$ be an abelian variety defined over an algebraically closed field $k$. We consider theta groups associated to \emph{simple semi-homogenous vector bundles of separable type} on $X$. We determine the structure and representation theory of these groups. In doing so we relate work of Mumford, Mukai, and Umemura.
openaire +2 more sources
The Dynamics of the Theta Method [PDF]
SIAM Journal on Scientific and Statistical Computing, 1991 In the dymanics of numerical methods for nonlinear differential equations there is a growing interest in specifying procedures that avoid the introduction of spurious solutions by time discretization [see \textit{A. Iserles} and the authors, SIAM J. Numer. Anal. 28, No. 6, 1723-1751 (1991)].
Stuart, A. M., Peplow, A. T.
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FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source