Results 161 to 170 of about 11,476 (205)

Naturally occurring variation in a cytochrome P450 modifies thiabendazole responses independently of beta-tubulin. [PDF]

PLoS Pathog
Collins JB, Dilks CM, Hahnel SR, Rodriguez B, Fox BW, Redman E, Yu J, Cooke B, Sihuta K, Zamanian M, Roy PJ, Schroeder FC, Gilleard JS, Andersen EC.   +13 more
europepmc   +1 more source

Exploring the Androgen Receptor Binding Affinity of Azole Derivatives through Multiscale Computational and Experimental Approaches. [PDF]

Environ Sci Technol
Pathak RK, Jeong DH, Jang MJ, Lee HS, Kim JM.   +4 more
europepmc   +1 more source

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Ocular Penetration of Thiabendazole

Archives of Ophthalmology, 1990
OcularToxocara canisinfection may cause decreased vision owing to direct retinal injury by theToxocaraorganism or by secondary effects related to inflammation and scarring. Several treatment modalities for ocular toxocariasis have been advocated, including systemic antiparasitic medications, photocoagulation, and vitreous surgery.
A M, Maguire, M A, Zarbin, T B, Connor, J, Justin   +3 more
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Thiabendazole in hookworm infection

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1966
Abstract Thiabendazole was administered orally to 100 patients infected with hookworms. 60% harboured A. duodenale and 40% N. americanus. The mean ova count per gramme of faeces was 7178 ± 5166. 5 dosage schedules were tried, and therapeutic efficiency was assessed by finding out the percentage reduction in egg count. With 100 mg. per kg.
D V, Sabharwal, S K, Tikare, S N, Saxena, P S, Gupta, H K, Chuttani   +4 more
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Micronodular cirrhosis after thiabendazole

Digestive Diseases and Sciences, 1989
Hepatotoxicity secondary to the administration of thiabendazole has been rare since this drug was produced in 1964. In 14 of 15 patients reported previously in the literature, severe intrahepatic cholestasis resolved within seven months of the onset of illness. A recent report documented the progression to cirrhosis in a 15th patient.
M A, Roy, F W, Nugent, H T, Aretz
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Anticonvulsant action of thiabendazole

European Journal of Pharmacology, 1977
Thiabendazole was found to be specifically effective against maximal electroshock seizures in albino rats. It produced a significant dose-dependent decrease in the duration of the tonic extensor phase of hind legs. The ED50 was similar for oral or s.c. administration.
C, Shashindran, I S, Gandhi, N S, Parmar
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Thiabendazole in Pinworm Infestations

Archives of Pediatrics & Adolescent Medicine, 1965
THIABENDAZOLE HIABENDAZOLE * (2- (4′ Thiazolyl)-benzimidazole) has been used extensively as a veterinary anthelmintic. More recently it has been employed in the treatment of various human parasitic infestations, including strongyloidiasis, ascariasis, hookworm, trichuriasis, creeping eruption, and trichinosis.
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Thiabendazole in human filariasis

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1966
Abstract Thiabendazole was used in the treatment of patients with Loa loa, A. perstans and O. volvulus infections, in a dose of 25 mg. per kg. twice a day for 5–10 days, and was found ineffective. This study was prompted by its reported efficacy in the treatment of tropical eosinophilia and trichinosis.
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Thiabendazole

2021
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