Results 91 to 100 of about 89,923 (337)

Thiamine, gastrointestinal beriberi and acetylcholine signaling

Frontiers in Nutrition
Research has highlighted numerous detrimental consequences of thiamine deficiency on digestive function. These range from impaired gastric and intestinal motility to aberrant changes in pancreatic exocrine function, gastric acidity and disturbances in ...
Elliot Overton, Alina Emelyanova, Victoria I. Bunik, Victoria I. Bunik, Victoria I. Bunik   +4 more
doaj   +1 more source

Variability and Heritability of Thiamine Pharmacokinetics With Focus on OCT1 Effects on Membrane Transport and Pharmacokinetics in Humans

Clinical pharmacology and therapy, 2020
Thiamine is substrate of the hepatic uptake transporter organic cation transporter 1 (OCT1), and pathological lipid metabolism was associated with OCT1‐dependent thiamine transport.
Ole Jensen, J. Matthaei, Felix G. Blome, M. Schwab, M. Tzvetkov, J. Brockmöller   +5 more
semanticscholar   +1 more source

Pediatric intestinal pseudo‐obstruction found in 3‐year‐old male with Rett‐related mutation of methyl‐CpG binding protein 2

JPGN Reports, EarlyView.
Abstract A 3‐year‐old male with chronic abdominal distention, constipation, and severe malnutrition is diagnosed with pediatric intestinal pseudo‐obstruction (PIPO) after extensive evaluation that excluded mechanical, malabsorptive, metabolic, inflammatory, and infectious causes. Aside from speech delay, he has a normal neurologic exam.
Angela Tran, Namrata Patel‐Sanchez
wiley   +1 more source

Pathway Editing Targets for Thiamine Biofortification in Rice Grains

Frontiers in Plant Science, 2018
Thiamine deficiency is common in populations consuming polished rice as a major source of carbohydrates. Thiamine is required to synthesize thiamine pyrophosphate (TPP), an essential cofactor of enzymes of central metabolism. Its biosynthesis pathway has
Anu P. Minhas, Rakesh Tuli, Sanjeev Puri
doaj   +1 more source

Hydrocortisone, Ascorbic Acid and Thiamine (HAT Therapy) for the Treatment of Sepsis. Focus on Ascorbic Acid

Nutrients, 2018
Sepsis is a devastating disease that carries an enormous toll in terms of human suffering and lives lost. Over 100 novel pharmacologic agents that targeted specific molecules or pathways have failed to improve the outcome of sepsis.
P. Marik
semanticscholar   +1 more source

The Management of Parkinson's Disease Before, during and after Pregnancy—an MDS Scientific Issues Committee Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Pregnancy after a Parkinson's diagnosis presents complex challenges. Due to the paucity of literature, there is no evidence‐based guidelines and protocols for preconception care, management of pregnancy, childbirth and the postpartum period in women with early‐onset Parkinson's disease (PD).
Alexander C. Lehn, Jee‐Young Lee, Giorgia Sciacca, Stacy Patterson, Adam Morton, Paul Pun, Walaa A. Kamel, Marina Picillo, Bart Post, Eng‐King Tan, Tamine Capato, Bastiaan R. Bloem, Manon Auffret, Annelien M. Oosterbaan, Willanka Kapelle, Michiko K. Bruno, Lorraine V. Kalia, Jeffrey H. Kordower, Daniela Berg   +18 more
wiley   +1 more source

A Retrospective Case Series of Thiamine Deficiency in Non-Alcoholic Hospitalized Veterans: An Important Cause of Delirium and Falling? [PDF]

, 2021
Elisabeth Mates, Deepti Alluri, Tailer Artis, Mark S. Riddle   +3 more
openalex   +1 more source

Early Vitamin C and Thiamine Administration to Patients with Septic Shock in Emergency Departments: Propensity Score-Based Analysis of a Before-and-After Cohort Study

Journal of Clinical Medicine, 2019
Background: Intravenous vitamin C and thiamine administration may be a potential adjuvant therapy for septic shock. We aimed to investigate the impact of early vitamin C and thiamine administration in septic shock patients.
T. Shin, Youn-Jung Kim, S. Ryoo, S. Hwang, I. Jo, S. Chung, Sung-Hyuk Choi, G. Suh, W. Kim   +8 more
semanticscholar   +1 more source

GmPGL1, a Thiamine Thiazole Synthase, Is Required for the Biosynthesis of Thiamine in Soybean

Frontiers in Plant Science, 2019
Thiamine is an essential cofactor in several enzymatic reactions for all living organisms. Animals cannot synthesize thiamine and depend on their diet.
Xingxing Feng, Xingxing Feng, Suxin Yang, Kuanqiang Tang, Kuanqiang Tang, Yaohua Zhang, Jiantian Leng, Jingjing Ma, Jingjing Ma, Quan Wang, Quan Wang, Xianzhong Feng   +11 more
doaj   +1 more source

The Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) Protocol: a prospective, multi-center, double-blind, adaptive sample size, randomized, placebo-controlled, clinical trial

Trials, 2019
BackgroundSepsis accounts for 30% to 50% of all in-hospital deaths in the United States. Other than antibiotics and source control, management strategies are largely supportive with fluid resuscitation and respiratory, renal, and circulatory support ...
D. Hager, M. Hooper, G. Bernard, L. Busse, E. W. Ely, A. Fowler, D. Gaieski, A. Hall, J. Hinson, J. Jackson, G. Kelen, M. Levine, C. Lindsell, Richard E Malone, A. McGlothlin, R. Rothman, K. Viele, D. Wright, J. Sevransky, G. Martin   +19 more
semanticscholar   +1 more source