Pathway Editing Targets for Thiamine Biofortification in Rice Grains
Frontiers in Plant Science, 2018 Thiamine deficiency is common in populations consuming polished rice as a major source of carbohydrates. Thiamine is required to synthesize thiamine pyrophosphate (TPP), an essential cofactor of enzymes of central metabolism. Its biosynthesis pathway has
Anu P. Minhas, Rakesh Tuli, Sanjeev Puri
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Not all weight loss is psychiatric: Diagnostic bias in pediatric Crohn's disease
JPGN Reports, EarlyView.Abstract Crohn's disease (CD) is a chronic inflammatory bowel disease (IBD) that can often be misdiagnosed, particularly in the female population. This is especially true in the initial stages, which are frequently characterized by weight loss and, at times, dietary intake restriction.
Karolina Aleksandra Jamrozik +7 more
wiley +1 more source
Covalently bound substrate at the regulatory site triggers allosteric enzyme activation [PDF]
, 2008 The mechanism by which the enzyme pyruvate decarboxylase from yeast is activated allosterically has been elucidated. A total of seven three-dimensional structures of the enzyme, of enzyme variants or of enzyme complexes form two yeast species (three of ...
Georg Wille +5 more
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Osmotic, oxidative and salinity stresses upregulate the expressions of Thiamine (vitamin B1) biosynthesis genes (THIC and THI1/THI4) in oil palm (Elaeis guineensis) [PDF]
, 2016 Thiamine or vitamin B1 comprises a pyrimidine moiety and a thiazole moiety. Thiamine pyrophosphate (TPP), the active form of thiamine, acts as a cofactor for various major enzymes for example transketolase (TK), α-ketoglutarate dehydrogenase (KGDH) and ...
Abdul Rahman, Nur Syuhadah +4 more
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Movement Disorders Clinical Practice, EarlyView.ABSTRACT Background Classifying abnormal tongue movements is challenging due to their varied presentations and limited visibility compared to other body parts. Accurate identification of the phenomenology guides physical examination and can point to specific diagnoses.
Nathaniel Bendahan +4 more
wiley +1 more source
Clinical Medicine Insights: Endocrinology and Diabetes, 2014 Thiamine deficiency has been documented to be prevalent in patients with diabetes mellitus, and correction of thiamine deficiency in this population may provide beneficial effects in several cardiometabolic parameters, including prevention of impending ...
Omar Al-Attas +5 more
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Processed Rice in Hawaii: Nutritive Value, Susceptibility to Insect Infestation and Consumer Acceptance as Compared with White and Brown Rice [PDF]
, 1950 Factors affecting the nutritive value and use of processed rice In Hawaii have been studied. Twenty-two samples of processed rice have been found to have an average thiamine content of 193 micrograms per 100 grams.
Hartzler, Eva +2 more
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Generation of Lamprey Monoclonal Antibodies (Lampribodies) Using the Phage Display System. [PDF]
, 2019 The variable lymphocyte receptors (VLRs) consist of leucine rich repeats (LRRs) and comprise the humoral antibodies produced by lampreys and hagfishes.
Amemiya, Chris T +3 more
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Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends
Med Research, EarlyView.The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley +1 more source
GmPGL1, a Thiamine Thiazole Synthase, Is Required for the Biosynthesis of Thiamine in Soybean
Frontiers in Plant Science, 2019 Thiamine is an essential cofactor in several enzymatic reactions for all living organisms. Animals cannot synthesize thiamine and depend on their diet.
Xingxing Feng +11 more
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