Results 121 to 130 of about 112,496 (296)

Off‐Label Manipulation of Paediatric Medication Remains a Challenge in Clinical Practice: An Observational Study

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim The aim was to observe the methods used for off‐label manipulation of medication on Norwegian paediatric wards. Methods This prospective observational study used a digital form to collect information on how medicine was manipulated on five paediatric wards in four university and local hospitals, from October 2023 to May 2024.
Randi Hamre Svendsen   +4 more
wiley   +1 more source

Substrate transport and drug interaction of human thiamine transporters SLC19A2/A3

open access: yesNature Communications
Thiamine and pyridoxine are essential B vitamins that serve as enzymatic cofactors in energy metabolism, protein and nucleic acid biosynthesis, and neurotransmitter production.
Peipei Li   +13 more
doaj   +1 more source

A non-alcoholic case of Wernicke's encephalopathy [PDF]

open access: yes, 2000
Wernicke's encephalopathy is an acute neurological disease caused by thiamine deficiency. Alcoholism is the most important risk factor. Recently, non-alcoholic cases are increasingly being recognised.
Cheung, RTF, Lee, N
core  

Updates on Mediterranean diet and health status: active ingredients and pharmacological mechanisms

open access: yesBritish Journal of Pharmacology, EarlyView.
The Mediterranean diet (MedDiet) is among the most extensively studied dietary patterns and has been consistently associated with reduced risk of all‐cause mortality, cardiovascular disease, metabolic disorders, cognitive decline and several types of cancers.
Lukas Schwingshackl   +3 more
wiley   +1 more source

Single‐Cell Virtual Perturbation Screening Identifies STAT3 as a Key Regulator of Dentinogenesis

open access: yesCell Proliferation, EarlyView.
STAT3 promotes odontoblast differentiation in dental mesenchymal cells by transcriptionally regulating WNT2B via the canonical Wnt/β‐catenin signalling pathway. These findings elucidate a mechanism underlying dentine development. ABSTRACT Dentine formation constitutes a physiological process precisely regulated by signal transduction modules governing ...
Yanfei Zhu   +12 more
wiley   +1 more source

Thiamine-responsive megaloblastic anemia: early diagnosis may be effective in preventing deafness

open access: yesThe Turkish Journal of Pediatrics, 2009
Thiamine-responsive megaloblastic anemia syndrome is an autosomal recessive disorder characterized by diabetes mellitus, megaloblastic anemia and sensorineural hearing loss.
Hasan Onal   +7 more
doaj  

Repeatability and validity of a food frequency questionnaire in free-living older people in relation to cognitive function [PDF]

open access: yes, 2008
Objectives: To determine the repeatability and validity of a self-administered, 175-item food frequency questionnaire (FFQ) in free-living older people and to assess whether these are influenced by cognitive function.
Aucott, Lorna S   +4 more
core  

Clinical and genetic characterization of intellectual disability

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
This study examines the etiological factors and comorbidities in a large cohort of Finnish patients with intellectual disability. Genetic causes—including chromosomal abnormalities and pathogenic gene variants—were more frequently identified in individuals with moderate to profound intellectual disability.
Aarni Venetvaara   +14 more
wiley   +1 more source

A Case of Anaphylaxis to Intramuscular but Not to Oral Application of Thiamine (Vitamin B1)

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2018
We report a 78 year-old non-atopic female with polyneuropathy who started to receive monthly intramuscular injections of thiamine hydrochloride. She had an anaphylaxis after the fourth injection.
Stefanie Aurich   +2 more
doaj  

Air embolism secondary to suspected lymphatic tissue disruption with severe exercise‐induced pulmonary haemorrhage

open access: yesEquine Veterinary Education, EarlyView.
Summary Air embolism is rare in horses and typically associated with complications following intravenous catheterisation or other medical procedures. Exercise‐induced pulmonary haemorrhage (EIPH) is common in racehorses but not usually associated with air embolism. This report describes a case of air embolism in a 4‐year‐old Thoroughbred with EIPH. The
J. Wittenberg   +7 more
wiley   +1 more source

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