Results 131 to 140 of about 112,496 (296)
S‐Adenosylmethionine (SAM) hydrolases counter increased SAM epimerisation in thermophilic archaea
The FEBS Journal, EarlyView.S‐Adenosyl‐l‐methionine (SAM) is a vital enzyme cofactor. Epimerisation at the sulfonium centre of biologically active (SS,SCα)‐SAM is driven by heat, yielding biologically inactive (RS,SCα)‐SAM. Here, two novel archaeal SAM hydrolases from the thermophilic Sulfolobus acidocaldarius and the halophilic Haloferax volcanii are shown to cleave (RS,SCα)‐SAM.
Agnes Bartels +7 more
wiley +1 more source
The FEBS Journal, EarlyView.Using 1H NMR metabolomics, we measured polar and lipid metabolites from human blood neutrophils from people with frailty (n = 31, mean age 84Y), people with rheumatoid arthritis (n = 16, mean age 55Y), robust older (n = 24, mean age 66Y) and healthy younger people (n = 21, mean age 22Y).
Genna Ali Abdullah +5 more
wiley +1 more source
Sex‐Specific Atlantic Salmon Upstream Passage and Fallback at a Natural Cascade After Dam Removal
Fisheries Management and Ecology, EarlyView.ABSTRACT In the Boquet River (NY, USA) a low‐head dam set above a ~200‐m bedrock cascade was removed in 2015. We used radio‐telemetry to assess landlocked Atlantic salmon passage at the remaining cascade (2020, 2022). Across years, 52% of males (13/25) attempted cascade passage whereas females made no discernable attempts (0/11).
Kurt C. Heim +5 more
wiley +1 more source
The Implications of Atlantic Salmon (Salmo salar L.) Fatty Acid Profiles for Their Thiamine Status
Ecology and EvolutionThiamine deficiency is an ongoing issue across the Northern Hemisphere, causing reproductive failure in multiple salmonid populations. In the Baltic Sea, a large brackish water system in northern Europe, previous research has suggested that this ...
Vittoria Todisco +6 more
doaj +1 more source
International Journal of Cosmetic Science, EarlyView.Microalgae extracts show immense potential in cosmetics for their bioactivities; emerging extraction techniques enhance bioactive compound yield from microalgae. Abstract Microalgae have attracted significant interest in numerous sectors, particularly in the cosmetic industries, owing to their rich composition of bioactive compounds. This paper aims to
Alireza Mousakhani Ganjeh +5 more
wiley +1 more source
Associative learning and thiamine based flavor preference [PDF]
The current experiment explored the extent to which thiamine deficiency at the time of conditioning is important as well as the importance of thiamine deficiency at the time of testing. This experiment controlled for previous experiments' flaws.
Richardson, Rachel Anne
core
Immunology &Cell Biology, EarlyView.VitBAg antigen presentation is promoted through a cytosolic pathway that reaches ligand‐receptive MR1 to present to MAIT cells, like the riboflavin transport pathway. Riboflavin solute carrier transporters can promote this MR1 presentation, but they are not essential for this role, suggesting redundant pathways to uptake VitBAg.
Sebastian Cruz‐Gomez +10 more
wiley +1 more source
Alcohol consumption and risk of dementia: a systematic review and meta‐analysis
Internal Medicine Journal, EarlyView.Abstract To examine the relationship between alcohol intake and the risk of developing dementia, we conducted a comprehensive search of PubMed, Embase, Cochrane Library and Web of Science databases for relevant studies up to July 22, 2024. The quality of the original studies was appraised utilising the Newcastle‐Ottawa Scale (NOS).
Ren Zhang, Baitao Li, Yue Miao
wiley +1 more source
Building a Digital Health Innovation Ecosystem: Tech‐Push, Demand‐Pull, and Government Policy
Information Systems Journal, EarlyView.ABSTRACT Health and social care are at a pivotal point, encountering complex and multifaceted systemic and workforce‐related challenges. Governments have identified the need to redefine health and social care services to address the evolving needs of both patients and service providers.
Denis Dennehy +4 more
wiley +1 more source
De novo stolon organogenesis in potato leaf callus elicited by Agrobacterium tumefaciens stimulus
Journal of Integrative Plant Biology, EarlyView.Agrobacterium tumefaciens triggers stolon regeneration from potato leaf callus independent of T‐DNA insertion, suggesting a strategy to reprogram callus identity and expand the potential of tissue regeneration. ABSTRACT Plant cells can undergo cellular reprogramming, enabling pluripotent callus formation from excised leaves.
Seung Yong Shin +7 more
wiley +1 more source