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Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency in Children and Adults [PDF]
Thiamine (vitamin B1) is an essential nutrient that serves as a cofactor for a number of enzymes, mostly with mitochondrial localization. Some thiamine-dependent enzymes are involved in energy metabolism and biosynthesis of nucleic acids whereas others ...
Shibani Dhir +4 more
doaj +4 more sources
Hiding in Plain Sight: Modern Thiamine Deficiency [PDF]
Thiamine or vitamin B1 is an essential, water-soluble vitamin required for mitochondrial energetics—the production of adenosine triphosphate (ATP). It is a critical and rate-limiting cofactor to multiple enzymes involved in this process, including those ...
Chandler Marrs, Derrick Lonsdale
doaj +2 more sources
Thiamine Deficiency in Surgical Patients
William W. Coon, Earl F. Wolfman
openalex +5 more sources
Early rearing of steelhead (Oncorhynchus mykiss) in Oregon hatcheries is often problematic; fry can become emaciated and die during the period between hatch and first feed. Thiamine (vitamin B1) deficiency has caused early mortality in salmonids; however,
Aimee N. Reed +3 more
doaj +1 more source
The Prevalence of Thiamine Deficiency and Associated Factors among Adult Population in Shiraz, Southern Iran [PDF]
Background: Thiamine is an essential nutrient, and its deficiency is accompanied by nervous and cardiovascular disorders. This study aimed to assess the prevalence of thiamine deficiency and associated factors among adults in Shiraz, southern Iran ...
Zahra Hassanzadeh-Rostami +5 more
doaj +1 more source
Severe thiamine deficiency in eastern Baltic cod (Gadus morhua).
The eastern Baltic cod (Gadus morhua) population has been decreasing in the Baltic Sea for at least 30 years. Condition indices of the Baltic cod have decreased, and previous studies have suggested that this might be due to overfishing, predation, lower ...
Josefin Engelhardt +6 more
doaj +1 more source
High-dose thiamine prevents brain lesions and prolongs survival of Slc19a3-deficient mice. [PDF]
SLC19A3 deficiency, also called thiamine metabolism dysfunction syndrome-2 (THMD2; OMIM 607483), is an autosomal recessive neurodegenerative disorder caused by mutations in SLC19A3, the gene encoding thiamine transporter 2.
Kaoru Suzuki +5 more
doaj +1 more source
Thiamine deficiency and oxalosis [PDF]
Type I hyperoxaluria results from reduced activity of α-ketoglutarate: glyoxylate carboligase, which is necessary for the synergistic decarboxylation of glyoxylate and α-ketoglutarate to α-hydroxy-β-keto-adipate.Since thiamine pyrophosphate is a cofactor in the reaction, thiamine deficiency might be expected to result in tissue oxalosis. However, there
Diane C. Salyer, William R. Salyer
openaire +3 more sources
Neonatal cardiomyopathy and lactic acidosis responsive to thiamine [PDF]
A congestive cardiomyopathy was diagnosed in a girl at the age of 4 weeks. In the weeks following she developed general muscle hypotonia and plasma lactate increased to 8.5 mmol/L.
Abeling, N.G.G.M. (Nicolaas) +5 more
core +5 more sources
Thiamine is essential for the activity of several enzymes associated with energy metabolism in humans. Chronic alcohol use is associated with deficiency of thiamine along with other vitamins through several mechanisms.
Samir Kumar Praharaj +4 more
doaj +1 more source

