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Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency in Children and Adults [PDF]

open access: yesFrontiers in Psychiatry, 2019
Thiamine (vitamin B1) is an essential nutrient that serves as a cofactor for a number of enzymes, mostly with mitochondrial localization. Some thiamine-dependent enzymes are involved in energy metabolism and biosynthesis of nucleic acids whereas others ...
Shibani Dhir   +4 more
doaj   +5 more sources

Prevalence of Thiamine Deficiency in Pregnancy and its impact on fetal outcome in an area endemic for thiamine deficiency. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2023
BackgroundPregnancy is a metabolically challenging state with increased nutritional demand. Thiamine is an important cofactor in various metabolic pathways and thus its deficiency could have a serious impact on both maternal and fetal outcomes.
Ozaifa Kareem   +7 more
doaj   +3 more sources

Hiding in Plain Sight: Modern Thiamine Deficiency

open access: yesCells, 2021
Thiamine or vitamin B1 is an essential, water-soluble vitamin required for mitochondrial energetics—the production of adenosine triphosphate (ATP). It is a critical and rate-limiting cofactor to multiple enzymes involved in this process, including those ...
Chandler Marrs, Derrick Lonsdale
doaj   +2 more sources

Thiamine deficiency‐related neuropathy: A reversible entity from an endemic area [PDF]

open access: yesEur J Neurol, 2023
Despite thiamine deficiency being a lesser‐known entity in modern times, beriberi in various forms, including thiamine deficiency‐related neuropathy, remains endemic in Kashmir due to the consumption of polished rice as a staple food.
S. Nisar   +6 more
semanticscholar   +2 more sources

Thiamine deficiency in pregnancy and lactation: implications and present perspectives [PDF]

open access: yesFront Nutr, 2023
During pregnancy, many physiologic changes occur in order to accommodate fetal growth. These changes require an increase in many of the nutritional needs to prevent long-term consequences for both mother and the offspring.
Ozaifa Kareem   +4 more
semanticscholar   +2 more sources

Severe thiamine deficiency in eastern Baltic cod (Gadus morhua).

open access: yesPLoS ONE, 2020
The eastern Baltic cod (Gadus morhua) population has been decreasing in the Baltic Sea for at least 30 years. Condition indices of the Baltic cod have decreased, and previous studies have suggested that this might be due to overfishing, predation, lower ...
Josefin Engelhardt   +6 more
doaj   +2 more sources

High-dose thiamine strategy in Wernicke–Korsakoff syndrome and related thiamine deficiency conditions associated with alcohol use disorder

open access: yesIndian Journal of Psychiatry, 2021
Thiamine is essential for the activity of several enzymes associated with energy metabolism in humans. Chronic alcohol use is associated with deficiency of thiamine along with other vitamins through several mechanisms.
Samir Kumar Praharaj   +4 more
doaj   +2 more sources

Thiamine deficiency: a commonly unrecognised but easily treatable condition [PDF]

open access: yesPostgrad Med J, 2022
Thiamine is present in many foods and is well recognised as an essential nutrient critical for energy metabolism. While thiamine deficiency is commonly recognised in alcoholism, it can present in many other settings where it is often not considered and ...
T. Schostak   +3 more
semanticscholar   +2 more sources

Thiamine deficiency secondary to intestinal surgery leading to shoshin beriberi and Wernicke encephalopathy: a case report [PDF]

open access: yesFrontiers in Pediatrics
PurposeThiamine is an essential micronutrient, and its deficiency, also known as beriberi, can have significant clinical implications. Thiamine deficiency impairs oxidative metabolic pathways, leading to reduced adenosine triphosphate (ATP) synthesis and
Peiyu Huang   +3 more
doaj   +2 more sources

Cross-Sectional Study of Thiamine Deficiency and Its Associated Risks in Emergency Care [PDF]

open access: yesWestern Journal of Emergency Medicine
Background: Growing data indicates that thiamine deficiency occurs during acute illness in the absence of alcohol use disorder. Our primary objective was to measure clinical factors associated with thiamine deficiency in patients with sepsis, diabetic ...
Joseph Miller   +9 more
doaj   +2 more sources

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