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Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency in Children and Adults [PDF]

open access: yesFrontiers in Psychiatry, 2019
Thiamine (vitamin B1) is an essential nutrient that serves as a cofactor for a number of enzymes, mostly with mitochondrial localization. Some thiamine-dependent enzymes are involved in energy metabolism and biosynthesis of nucleic acids whereas others ...
Shibani Dhir   +4 more
doaj   +4 more sources

Hiding in Plain Sight: Modern Thiamine Deficiency [PDF]

open access: yesCells, 2021
Thiamine or vitamin B1 is an essential, water-soluble vitamin required for mitochondrial energetics—the production of adenosine triphosphate (ATP). It is a critical and rate-limiting cofactor to multiple enzymes involved in this process, including those ...
Chandler Marrs, Derrick Lonsdale
doaj   +2 more sources

Thiamine Supplementation Improves Survival and Body Condition of Hatchery-Reared Steelhead (Oncorhynchus mykiss) in Oregon

open access: yesVeterinary Sciences, 2023
Early rearing of steelhead (Oncorhynchus mykiss) in Oregon hatcheries is often problematic; fry can become emaciated and die during the period between hatch and first feed. Thiamine (vitamin B1) deficiency has caused early mortality in salmonids; however,
Aimee N. Reed   +3 more
doaj   +1 more source

The Prevalence of Thiamine Deficiency and Associated Factors among Adult Population in Shiraz, Southern Iran [PDF]

open access: yesInternational Journal of Nutrition Sciences, 2020
Background: Thiamine is an essential nutrient, and its deficiency is accompanied by nervous and cardiovascular disorders. This study aimed to assess the prevalence of thiamine deficiency and associated factors among adults in Shiraz, southern Iran ...
Zahra Hassanzadeh-Rostami   +5 more
doaj   +1 more source

Severe thiamine deficiency in eastern Baltic cod (Gadus morhua).

open access: yesPLoS ONE, 2020
The eastern Baltic cod (Gadus morhua) population has been decreasing in the Baltic Sea for at least 30 years. Condition indices of the Baltic cod have decreased, and previous studies have suggested that this might be due to overfishing, predation, lower ...
Josefin Engelhardt   +6 more
doaj   +1 more source

High-dose thiamine prevents brain lesions and prolongs survival of Slc19a3-deficient mice. [PDF]

open access: yesPLoS ONE, 2017
SLC19A3 deficiency, also called thiamine metabolism dysfunction syndrome-2 (THMD2; OMIM 607483), is an autosomal recessive neurodegenerative disorder caused by mutations in SLC19A3, the gene encoding thiamine transporter 2.
Kaoru Suzuki   +5 more
doaj   +1 more source

Thiamine deficiency and oxalosis [PDF]

open access: yesJournal of Clinical Pathology, 1974
Type I hyperoxaluria results from reduced activity of α-ketoglutarate: glyoxylate carboligase, which is necessary for the synergistic decarboxylation of glyoxylate and α-ketoglutarate to α-hydroxy-β-keto-adipate.Since thiamine pyrophosphate is a cofactor in the reaction, thiamine deficiency might be expected to result in tissue oxalosis. However, there
Diane C. Salyer, William R. Salyer
openaire   +3 more sources

Neonatal cardiomyopathy and lactic acidosis responsive to thiamine [PDF]

open access: yes, 1991
A congestive cardiomyopathy was diagnosed in a girl at the age of 4 weeks. In the weeks following she developed general muscle hypotonia and plasma lactate increased to 8.5 mmol/L.
Abeling, N.G.G.M. (Nicolaas)   +5 more
core   +5 more sources

High-dose thiamine strategy in Wernicke–Korsakoff syndrome and related thiamine deficiency conditions associated with alcohol use disorder

open access: yesIndian Journal of Psychiatry, 2021
Thiamine is essential for the activity of several enzymes associated with energy metabolism in humans. Chronic alcohol use is associated with deficiency of thiamine along with other vitamins through several mechanisms.
Samir Kumar Praharaj   +4 more
doaj   +1 more source

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