Results 31 to 40 of about 19,767 (240)

Practical Recommendations of the Obesity Management Task Force of the European Association for the Study of Obesity for the Post-Bariatric Surgery Medical Management [PDF]

, 2017
Bariatric surgery is today the most effective long-term therapy for the management of patients with severe obesity, and its use is recommended by the relevant guidelines of the management of obesity in adults.
Azran, Carmil, Batterham, Rachel L, Busetto, Luca, Dicker, Dror, Farpour-Lambert, Nathalie, Fried, Martin, Hjelmes\ue6th, J\uf8ran, Kinzl, Johann, Leitner, Deborah R, Makaronidis, Janine M, Schindler, Karin, Toplak, Hermann, Yumuk, Volkan   +12 more
core   +6 more sources

Thiamine pyrophosphokinase deficiency: report of two Chinese cases and a literature review

Frontiers in Pediatrics, 2023
Thiamine pyrophosphokinase (TPK) deficiency, is a rare autosomal recessive disorder of congenital metabolic dysfunction caused by variants in the TPK1 gene.
Dan Zhao, Ming Liu, Huafang Jiang, Tianyu Song, Chaolong Xu, Xin Duan, Ruoyu Duan, Han Xu, Zhimei Liu, Fang Fang   +9 more
doaj   +1 more source

Wernicke encephalopathy complicating catatonic schizophrenia

European Psychiatry, 2021
Introduction Wernicke’s encephalopathy is a potentially fatal neurological emergency caused by thiamine deficiency. Although it is often associated with chronic alcoholism, it can also occur in all situations that lead to a thiamine deficiency such as ...
C. Rihab, S. Ellouze, N. Messedi, M. Turki, F. Ben Ali, W. Abid, M. Halouani, J. Aloulou   +7 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Molecular mechanisms of the non-coenzyme action of thiamin in brain. Biochemical, structural and pathway analysis [PDF]

, 2015
Thiamin (vitamin B1) is a pharmacological agent boosting central metabolism through the action of the coenzyme thiamin diphosphate (ThDP). However, positive effects, including improved cognition, of high thiamin doses in neurodegeneration may be ...
Andrey, Vovk, Contestabile, Roberto, DI SALVO, Martino Luigi, Garik, Mkrtchyan, Lucien, Bettendorff, Parroni, Alessia, Thilo, Kaehne, Vasily, Aleshin, Victoria, Bunik, Yulia, Parkhomenko   +9 more
core   +1 more source

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

Advanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen, Ruqiao Duan, Cunzheng Zhang, Gaonan Li, XiaoLin Ji, Qi Zhang, Fei Pei, Kun Wang, Liping Duan   +8 more
wiley   +1 more source

A Patient With Thiamine Deficiency Exhibiting Muscle Edema Suggested by MRI

Frontiers in Neurology, 2018
Myalgia is sometimes observed in patients with thiamine-deficiency neuropathy. However, the detailed mechanism(s) underlying muscular manifestations have been poorly elucidated.
Kenichiro Murate, Yasuaki Mizutani, Toshiki Maeda, Ryunosuke Nagao, Kouichi Kikuchi, Sayuri Shima, Yoshiki Niimi, Akihiro Ueda, Shinji Ito, Tatsuro Mutoh   +9 more
doaj   +1 more source

An audit of the changes in thiamine levels during higher caloric nutritional rehabilitation of adolescent patients hospitalised with a restrictive eating disorder

Journal of Eating Disorders, 2020
Background Routine supplementation of thiamine in patients with restrictive eating disorders prior to initiation of nutritional rehabilitation, is an example of a clinical guideline based on expert opinion rather than evidence-based recommendations. This
Elizabeth Parker, Terri Maister, Anita Stefoska-Needham, Christine Wearne, Gail Anderson, Linette Gomes, Simon Clarke, Michael Kohn   +7 more
doaj   +1 more source

Engineering an Optogenetic pH‐Modulator in Bacteria

Advanced Science, EarlyView.
ABSTRACT Cells in many naturally occurring organisms routinely cooperate to control their extracellular pH in a dynamic and reversible manner, but this capability has been underexplored in synthetic biology. Here, we sought to engineer a microbial system that switches between two states —high and low extracellular pH— with minimal human intervention ...
Jenevieve Kuang, Olivia J. Armendarez, Wei‐Ting Chang, Matthew M. Hausladen, Shanna Bonanno, Daniel J. Wilson, Neel S. Joshi, Leila F. Deravi   +7 more
wiley   +1 more source

Thiamine deficiency in diabetes, obesity and bariatric surgery: Recipes for diabetic ketoacidosis

Journal of Family Medicine and Primary Care
Diabetic ketoacidosis (DKA) is a life-threatening condition affecting individuals with diabetes characterised by hyperglycaemia, metabolic acidosis and ketonemia. The incidence and financial burden of DKA is still high.
Akhila Panda, Amirmohammad Heidari, Maryam Borumand, Musaab Ahmed, Ahmed Hassan, Mohamed H Ahmed   +5 more
doaj   +1 more source