Results 21 to 30 of about 919,128 (362)

Thiamine deficiency unrelated to alcohol consumption in high‐income countries: a literature review

open access: yesAnnals of the New York Academy of Sciences, 2021
Thiamine deficiency has been typically associated with alcoholism or as a prevalent problem in low‐ and middle‐income countries (LMICs) whose populations rely on staple foods with a low content of thiamine.
F. Gomes   +3 more
semanticscholar   +1 more source

High-dose thiamine strategy in Wernicke–Korsakoff syndrome and related thiamine deficiency conditions associated with alcohol use disorder

open access: yesIndian Journal of Psychiatry, 2021
Thiamine is essential for the activity of several enzymes associated with energy metabolism in humans. Chronic alcohol use is associated with deficiency of thiamine along with other vitamins through several mechanisms.
S. Praharaj   +4 more
semanticscholar   +1 more source

Thiamine deficiency disorders: a clinical perspective

open access: yesAnnals of the New York Academy of Sciences, 2020
Thiamine is an essential water‐soluble vitamin that plays an important role in energy metabolism. Thiamine deficiency presents many challenges to clinicians, in part due to the broad clinical spectrum, referred to as thiamine deficiency disorders (TDDs),
T. J. Smith   +6 more
semanticscholar   +1 more source

A fresh look at thiamine deficiency—new analyses by the global thiamine alliance

open access: yesAnnals of the New York Academy of Sciences, 2021
Severe thiamine (vitamin B1) deficiency is generally regarded as a problem affecting mostly infants in low‐income communities of Southeast Asia and adult alcoholics regardless of their location.
M. Bourassa   +2 more
semanticscholar   +1 more source

High-dose thiamine prevents brain lesions and prolongs survival of Slc19a3-deficient mice. [PDF]

open access: yesPLoS ONE, 2017
SLC19A3 deficiency, also called thiamine metabolism dysfunction syndrome-2 (THMD2; OMIM 607483), is an autosomal recessive neurodegenerative disorder caused by mutations in SLC19A3, the gene encoding thiamine transporter 2.
Kaoru Suzuki   +5 more
doaj   +1 more source

Thiamine deficiency and oxalosis [PDF]

open access: yesJournal of Clinical Pathology, 1974
Type I hyperoxaluria results from reduced activity of α-ketoglutarate: glyoxylate carboligase, which is necessary for the synergistic decarboxylation of glyoxylate and α-ketoglutarate to α-hydroxy-β-keto-adipate.Since thiamine pyrophosphate is a cofactor in the reaction, thiamine deficiency might be expected to result in tissue oxalosis. However, there
Diane C. Salyer, William R. Salyer
openaire   +3 more sources

Glucose-induced down regulation of thiamine transporters in the kidney proximal tubular epithelium produces thiamine insufficiency in diabetes [PDF]

open access: yes, 2012
Increased renal clearance of thiamine (vitamin B1) occurs in experimental and clinical diabetes producing thiamine insufficiency mediated by impaired tubular re-uptake and linked to the development of diabetic nephropathy.
A Adaikalakoteswari   +42 more
core   +11 more sources

Neonatal cardiomyopathy and lactic acidosis responsive to thiamine [PDF]

open access: yes, 1991
A congestive cardiomyopathy was diagnosed in a girl at the age of 4 weeks. In the weeks following she developed general muscle hypotonia and plasma lactate increased to 8.5 mmol/L.
Abeling, N.G.G.M. (Nicolaas)   +5 more
core   +5 more sources

Anaesthesia and intensive care management of shoshin beriberi in perioperative period in young adult

open access: yesAnnals of Cardiac Anaesthesia, 2023
Thiamine deficiency presents as dry and wet beriberi. Wet beriberi is a complication of the cardiovascular system. Acute form of wet beriberi known as Shoshin beriberi is an acute presentation of cardiogenic shock which is rapidly reversed with thiamine ...
Sujit J Kshirsagar   +2 more
doaj   +1 more source

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