Pharmacokinetics of high-dose oral thiamine hydrochloride in healthy subjects. [PDF]
Background: High dose oral thiamine may have a role in treating diabetes, heart failure, and hypermetabolic states. The purpose of this study was to determine the pharmacokinetic profile of oral thiamine hydrochloride at 100 mg, 500 mg and 1500 mg doses ...
Smithline HA, Donnino M, Greenblatt DJ.
europepmc +3 more sources
Physiological changes and reproductive performance in presence or absence of thiamine in the diet of Sterlet sturgeon, Acipenser ruthenus [PDF]
To evaluate the effects of thiamine (vitamin B1) on physiological changes and reproductive performance of Sterlet sturgeon (Acipenser ruthenus), 30 females (averaged 698 ± 15 g) were selected in maturity stage IV and were randomly distributed in six ...
Sareh Ghiasi, Bahram Falahatkar
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Wernicke's Encephalopathy Secondary to Hyperemesis Gravidarum in Pregnancy: A Case Report. [PDF]
ABSTRACT Wernicke's Encephalopathy, although classically associated with chronic alcoholism, can also occur during pregnancy as a complication of hyperemesis gravidarum and is often underdiagnosed. We report a case of a 34‐year‐old pregnant woman at 16 weeks of gestation who presented with prolonged vomiting, altered mental status, nystagmus, and gait ...
Mahato A +6 more
europepmc +2 more sources
Subclinical thiamine deficiency results in failed reproduction in Arctic foxes
Thiamine deficiency can result in life‐threatening physiological and neurological complications. While a thiamine‐deficient diet may result in the onset of such symptoms, the presence of thiaminase – an enzyme that breaks down thiamine – is very often ...
Craig Jackson +9 more
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Spectrophotometric Determination of Thiamine hydrochloride Via Oxidative Coupling Reaction Using 4-Aminoantipyrine [PDF]
A sensitive spectrophotometric method has been developed for the determination of thiamine hydrochloride by oxidative coupling reaction of thiamine with the reagent 4-aminoantipyrine (4-AAP) in the presence of copper sulphate as oxidizing agent in ...
Reem Al-Luhaiby, Mohammed Alenizzi
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A PAPER CHROMATOGRAPHIC METHOD FOR STABILITY INDICATING ASSAY OF THIAMINE HYDROCHLORIDE IN PHARMACEUTICAL PREPARATIONS [PDF]
Paper chromatographic separation of thiamine hydrochloride from its degradation products has been successfully carried out on Whatmann No. 1 chromatographic paper using n-butanol, acetic acid, acetone, water (45:20:10:25) as the developing system.
S. Shawky +3 more
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Background: Patients with alcohol use disorder (AUD) may develop peripheral edema due to alcohol-related liver, renal, or heart disease. Thiamine deficiency is reported to occur in AUD and type 2 diabetes mellitus (T2DM).
Hitomi Tanaka +6 more
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Glucose-induced down regulation of thiamine transporters in the kidney proximal tubular epithelium produces thiamine insufficiency in diabetes [PDF]
Increased renal clearance of thiamine (vitamin B1) occurs in experimental and clinical diabetes producing thiamine insufficiency mediated by impaired tubular re-uptake and linked to the development of diabetic nephropathy.
Larkin James R. +22 more
core +1 more source
In this research, an easy, acurate and rapid spectrophotometric method for determination of sulphite and thiamine hydrochloride is described. This method used proton transfer reaction between sulphite ion with alizarine at (pH 6.73) to develop red ...
Bassima A. Abed Al-Hadi
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THIAMINE IMPROVES LEAD-INDUCED NEUROTOXICITY IN RATS: BEHAVIORAL, BIOCHEMICAL AND STRUCTURAL ASSESSMENT [PDF]
This study was designed to investigate neuro-behavioral, neuro-biochemical and neuro-morphological alterations induced by sub-acute toxicity of lead (Pb) in male Wistar rats as well as the assessment of the neuroprotective effect of thiamine ...
OSAMA EL OKLE +2 more
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