Results 11 to 20 of about 7,079 (224)

2-(3-Oxo-3,4-dihydro-2H-1,4-benzothiazin-4-yl)acetamide [PDF]

Acta Crystallographica Section E, 2010
In the title compound, C10H10N2O2S, the thiazine ring approximates to an envelope form with the S atom in the flap position. The amide group attached to the acetate group is almost perpendicular to the mean plane of the thiazine ring [dihedral angle = 88.
Muhammad Salim, Shiyao Yang, Zaid Mahmood, Azher Saeed, Muhammad Saleem Akhtar   +4 more
doaj   +3 more sources

Thiosulfonate-Derived BODIPY "Stick and Glue" Strategy for Fluorescent Thiol Labeling. [PDF]

Angew Chem Int Ed Engl
We present a powerful photochemical strategy for converting disulfide bonds into stable thioether linkages via a [1,2]‐sigmatropic rearrangement. By integrating this reaction into traditional methanethiosulfonate‐based thiol labeling, we enable light‐triggered stabilization of peptide and protein conjugates with enhanced robustness and versatility ...
Šálková L, Dunlop D, Tütüncü BB, Knejzlík Z, Slanina T.   +4 more
europepmc   +3 more sources

Investigating the antiparasitic potential of the marine sesquiterpene avarone, its reduced form avarol, and the novel semisynthetic thiazinoquinone analogue thiazoavarone [PDF]

, 2020
The chemical analysis of the sponge Dysidea avara afforded the known sesquiterpene quinone avarone, along with its reduced form avarol. To further explore the role of the thiazinoquinone scaffold as an antiplasmodial, antileishmanial and antischistosomal
AIELLO, ANNA, Avunduk, Sibel, Basilico, Nicoletta, CASERTANO, MARCELLO, FATTORUSSO, CATERINA, Gimmelli, Roberto, Guidi, Alessandra, IMPERATORE, CONCETTA, LUCIANO, PAOLO, MENNA, MARIALUISA, Parapini, Silvia, PERSICO, MARCO, Ruberti, Giovina, Saccoccia, Fulvio   +13 more
core   +1 more source

Antiplasmodial activity of p-substituted benzyl thiazinoquinone derivatives and their potential against parasitic infections [PDF]

, 2020
Malaria is a life-threatening disease and, what is more, the resistance to available antimalarial drugs is a recurring problem. The resistance of Plasmodium falciparum malaria parasites to previous generations of medicines has undermined malaria control ...
Basilico, Nicoletta, Casertano, Marcello, Fattorusso, Caterina, Imperatore, Concetta, Menna, Marialuisa, Parapini, Silvia, Persico, Marco   +6 more
core   +2 more sources

The [4+2]‐Cycloaddition of α‐Nitrosoalkenes with Thiochalcones as a Prototype of Periselective Hetero‐Diels–Alder Reactions—Experimental and Computational Studies [PDF]

, 2020
The [4+2]‐cycloadditions of α‐nitrosoalkenes with thiochalcones occur with high selectivity at the thioketone moiety of the dienophile providing styryl‐substituted 4H‐1,5,2‐oxathiazines in moderate to good yields.
Boger D. L., Carruthers W., Corey E. J., Fleming I., Huisgen R., Huisgen R., Reissig H.-U., Warren S., Zweifel G. S.   +8 more
core   +1 more source

Effects of the substituents of pyrazole/thiazine ligands on the magnetic properties of chloro-bridged Cu(II) complexes [PDF]

, 2017
[Abstract] We have synthesised and characterised the dimeric copper(II) complexes [{CuCl(PzTz)}2(μ-Cl)2], [{CuCl(DMPzTz)}2(μ-Cl)2] and [{CuCl(DPhPzTz)}2(μ-Cl)2] and the monomeric complex [CuCl2(DMPzTz)] (PzTz = 2-(1-pyrazolyl)-1,3-thiazine, DMPzTz = 2-(3,
Bernalte-García, Álvaro, Esteban-Gómez, David, Luna-Giles, Francisco, Platas-Iglesias, Carlos, Torres-García, Pablo, Viñuelas-Zahínos, Emilio   +5 more
core   +2 more sources

Isomorphous diethyl 1-(4-chlorobenzyl)-4-(4-chlorophenyl)-2,2-dioxo-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[2,1-c][1,4]thiazine-1,3-dicarboxylate and its 1-(4-methylbenzyl)-4-(4-methylphenyl)-substituted analogue obeying the chloro–methyl exchange rule

Acta Crystallographica Section E: Crystallographic Communications, 2018
Accurate studies on the effect of substituents on the crystal packing are essential for understanding the intermolecular interactions and thus paving the way to crystal structure prediction.
R. Sribala, N. Srinivasan, S. Indumathi, R. V. Krishnakumar   +3 more
doaj   +1 more source

Crystal structure of Brinzolamide: a carbonic anhydrase inhibitor

Acta Crystallographica Section E: Crystallographic Communications, 2016
In crystal structure of the title compound, C12H21N3O5S3 [systematic name: (R)-4-ethylamino-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide], there exist three kinds of hydrogen-bonding interactions.
Huirong Zheng, Benyong Lou
doaj   +1 more source

Novel temperature-activated, humidity-sensitive optical sensor [PDF]

, 2017
A novel, colorimetric, temperature-activated humidity indicator is presented, with a colour change based on the semi-reversible aggregation of thiazine dyes (esp. methylene blue, MB) encapsulated within the polymer, hydroxypropyl cellulose (HPC).
Burns, Luke, Hawthorne, D., Hazafy, D., Mills, A.   +3 more
core   +1 more source

On the functionalization of benzo[e][2,1]thiazine

Beilstein Journal of Organic Chemistry, 2009
The reactions of benzo[e][2,1]thiazine-4-chloro-3-carbaldehydes 1 and benzo[e][2,1]thiazine-4-chloro-3-carbonitriles 2 with a number of oxidizing and reducing agents are reported.
Kirill Popov, Tatyana Volovnenko, Julian Volovenko   +2 more
doaj   +1 more source