Synthesis of 3,5-diaryltetrahydro-N- [(4’-nitroanilino)methyl-thiazine-1,1-dioxide and N-[(4’-methylanilino)methyl-]-1,4-thiazine-1,1-dioxides by condensing 3,5-diaryl-tetrahydro-1,4-thiazine-1,1-dioxide with formaldehyde and 4-nitroaniline/4 ...
V. Sundari +3 more
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2,3-Diphenyl-2,3-dihydro-4H-pyrido[3,2-e][1,3]thiazin-4-one
In the racemic title compound, C19H14N2OS, the two phenyl substituents on the 1,3-thiazine ring are almost perpendicular to the pyridine ring which is fused to the thiazine ring [inter-ring dihedral angles = 87.90 (8) and 85.54 (7)°].
Hemant P. Yennawar +2 more
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Lysine Methylation is an Endogenous Post-Translational Modification of Tau Protein in Human Brain and a Modulator of Aggregation Propensity [PDF]
Poster Division: Biological Sciences: 1st Place (The Ohio State University Edward F. Hayes Graduate Research Forum)Alzheimer’s Disease (AD) is the most common form of dementia, affecting 13% of Americans aged at least 65 years and 43% of Americans aged ...
Cooper, Grace
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3,4-Dihydro-2H-benzo[4,5]imidazo[2,1-b][1,3]thiazin-3-ol
In the title compound, C10H10N2OS, the benzimidazole ring system is almost planar (r.m.s. deviation = 0.007 Å), whereas the heterocyclic six-membered thiazine ring has an envelope conformation, with the hydroxy-substituted C atom as the flap.
Latifa El Ouasif +4 more
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Preferential utilization of NADPH as the endogenous electron donor for NAD(P)H:quinone oxidoreductase 1 (NQO1) in intact pulmonary arterial endothelial cells [PDF]
The goal was to determine whether endogenous cytosolic NAD(P)H:quinone oxidoreductase 1 (NQO1) preferentially uses NADPH or NADH in intact pulmonary arterial endothelial cells in culture.
Bongard, Robert D +3 more
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Synthesis and Antimicrobial Activity of 1,2-Benzothiazine Derivatives [PDF]
© 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).A number of 1,2 ...
Ann Hunter +12 more
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Kinetic-spectrophotometric method for the determination of trace amounts of bromide in seawater [PDF]
A novel simple, sensitive and rapid kinetic-spectrophotornetric method is proposed for the determination of trace amounts of bromide. The method is based on its catalytic effect on the oxidation of methylene blue (MB) by hydrogen peroxide in strongly ...
Motomizu, Shoji +4 more
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The title adduct, chlorido(2,3-diphenyl-3,4,5,6-tetrahydro-2H-1,3-thiazin-4-one-κO)triphenyltin, [Sn(C6H5)3Cl(C16H15NOS)], resulted from reaction of 2,3-diphenyl-3,4,5,6-tetrahydro-2H-1,3-thiazin-4-one with triphenyltin chloride. The thiazine ring has an
Hemant P. Yennawar +2 more
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The syntheses and crystal structures of two thiazinone compounds, namely, rac-2,3-diphenyl-2,3,5,6-tetrahydro-4H-1,3-thiazine-1,1,4-trione, C16H15NO3S, in its racemic form, and N-[(2S,5R)-1,1,4-trioxo-2,3-diphenyl-1,3-thiazinan-5-yl]acetamide ...
Hemant P. Yennawar +4 more
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Cellular Models of Aggregation-Dependent Template-Directed Proteolysis to Characterize Tau Aggregation Inhibitors for Treatment of Alzheimer's Disease [PDF]
Copyright © 2015, The American Society for Biochemistry and Molecular Biology. Acknowledgements-We thank Drs Timo Rager and Rolf Hilfiker (Solvias, Switzerland) for polymorph analyses.Peer reviewedPublisher ...
Clunas, Scott +14 more
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