Results 31 to 40 of about 2,922 (181)

Synthesis A New Bis Oxazine and Thiazine Derivatives and Study Their Biological Activities

Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2023
Oxazine and thiazine are heterocyclic organic compounds that have a wide range of pharmacological applications. In this study, some chalcone derivatives (1–5) were synthesized based on the reaction of an equal amount of p-substituted acetophenone and ...
Dina Saleem M. Ameen
doaj   +1 more source

Diverse reactivity of maleimides in polymer science and beyond

Polymer International, Volume 74, Issue 4, Page 296-306, April 2025.
This mini‐review provides a thorough overview of maleimide chemistry, highlighting its diverse reactivity in polymer and materials science applications. Abstract Maleimides are remarkably versatile functional groups, capable of participating in homo‐ and copolymerizations, Diels–Alder and (photo)cycloadditions, Michael additions, and other reactions ...
Bruce E Kirkpatrick, Kristi S Anseth, Tayler S Hebner   +2 more
wiley   +1 more source

rac-2,3-Diphenyl-2,3-dihydro-4H-pyrido[3,2-e][1,3]thiazin-4-one 1-oxide

IUCrData, 2017
In the title compound, C19H14N2O2S, the thiazine ring exhibits a screw-boat pucker. The oxygen atom on the sulfur atom of the ring is pseudo-axial on the thiazine ring.
Hemant P. Yennawar, Duncan J. Noble, Ziwei Yang, Lee J. Silverberg   +3 more
doaj   +1 more source

Microfluidic Intracytoplasmic Sperm Injection (MICSI): A Novel Platform for Sperm Isolation, Selection, and Injection Into Oocytes

Andrology, EarlyView.
ABSTRACT Background Infertility is a pressing global health concern, affecting one in six couples worldwide. The failure rate for assisted reproductive technologies (ART) cycles remains at approximately 78%, with limited improvements often attributed to a lack of technological innovation.
Mehran Dabiri, Dale Mark Goss, Steven Alexander Vasilescu, Majid Ebrahimi Warkiani   +3 more
wiley   +1 more source

Crystal structure of (E)-2-benzylidene-4-[(3-phenyl-4,5-dihydroisoxazol-5-yl)methyl]-2H-benzo[b][1,4]thiazin-3(4H)-one

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C25H20N2O2S, the dihydroisoxazole ring exhibits an envelope conformation with the methine atom being the flap, while the 1,4-thiazine ring displays a screw-boat conformation.
Nada Kheira Sebbar, Mohamed Ellouz, El Mokhtar Essassi, Mohamed Saadi, Lahcen El Ammari   +4 more
doaj   +1 more source

Potentiation effects of the positive allosteric modulator PTC‐174 on NMDA receptors in neonatal male rat substantia nigra dopaminergic neurons

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Positive allosteric modulators bind to secondary binding sites on the receptor and alter receptor conformation and activation, changing agonist potency and efficacy. PTC‐174 is a novel NMDA receptor positive allosteric modulator that particularly enhances activity of receptors containing GluN2C or GluN2D subunits.
Bangyuan Liu, Alasdair J. Gibb
wiley   +1 more source

Methyl 2-butyl-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-3-carboxylate

Acta Crystallographica Section E, 2012
In the title compound, C14H17NO5S, the thiazine ring adopts a half-chair conformation. The molecule exhibits an intramolecular O—H...O hydrogen bond, which forms a six-membered S(6) ring motif.
Muhammad Nadeem Arshad, Islam Ullah Khan, Muhammad Zia-ur-Rehman, Waseem Ahmed, Abdullah M. Asiri   +4 more
doaj   +1 more source

Co‐Culture of Mammalian Cells and Photosynthetic Microorganisms for Oxygen Supply in Engineered Tissues

Cell Proliferation, EarlyView.
Continuous 28‐day light exposure alters behaviours of articular cartilage progenitor cells (ACPCs) and mesenchymal stromal cells (MSCs). Co‐culture with Leptolyngbya and Synechococcus does not adversely affect the chondrogenic capacity of ACPCs over a 28‐day period, in contrast to co‐culture with Chlorella.
Meng Wang, Ahmad Furqan Hala, Vera van der Niet, Sebastian T. Bok, Aylin Kara Özenler, Marcel Janssen, Maria J. Barbosa, Dirk Martens, Rene H. Wijffels, Jos Malda, Mylène de Ruijter   +10 more
wiley   +1 more source

Complications and outcomes of standing flank versus ventral midline laparotomy for equine nephrosplenic entrapment

Equine Veterinary Education, EarlyView.
Summary Background Nephrosplenic entrapment (NSE) is a common surgical colic in horses. Ventral midline laparotomy (VML) under general anaesthesia (GA) is the standard approach, whereas standing flank laparotomy (SFL) is an alternative approach for surgical correction. However, direct comparisons between these approaches are lacking.
V. Santalucia, A. J. Tatz, B. Daeem, R. Dahan, M. Quint, G. Kelmer   +5 more
wiley   +1 more source

Design, evaluation, cytotoxic activity, molecular docking, ADMET analysis, and dynamic simulations and the preparation of new isoxazoles, thiazoles, 1,3-thiazines, and thiazolopyrimidines derived from quinoline-pyridopyrimidines

Pharmaceutical Biology
Context Quinoline, isoxazole, and pyridothiazolopyrimidinone derivatives are novel compounds with significant biological activity, exhibiting anticancer properties and holding promising therapeutic applications.Objective This investigation synthesized ...
Ameen A. Abu-Hashem, Nasser Amri, Ahmed F. El-Sayed   +2 more
doaj   +1 more source