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Thiazoles and Thiazolidinones as Antioxidants
Current Medicinal Chemistry, 2013Antioxidants are of great interest because of their involvement in important biological and industrial processes. According to Halliwell antioxidants are substances that at low concentration significantly delay or prevent oxidation. Chemically, oxidation is a process in which a loss of electrons occurs.
A A, Geronikaki, E P, Pitta, K S, Liaras
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Antiprotozoal thiazoles. 2-(5-Nitro-2-thienyl)thiazoles
Journal of Medicinal Chemistry, 1975A series of 2-(5-nitro-2-thienyl)thiazoles and their vinylogs having substituted methylamine side chains has been prepared by halogen displacement on the corresponding 4-chloromethylthiazole. Of these, 4-morpholinomethyl-2-(5-nitro-2-thienyl)thiazole showed moderate activity against Trypanosoma cruzi and Trypanosoma rhodesiense in mice.
J P, Verge, P, Roffey
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Thiazole-Mediated Synthetic Methodology
Chemical Reviews, 2004Review of synthetic schemes which have been developed in about 20 years of research by the use of thiazole-based methodology may serve to illustrate the potential of this approach in synthetic programs toward the construction of complex systems or special molecular fragments.
DONDONI, Alessandro, MARRA, Alberto
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Direct Arylation of Thiazoles on Water
Angewandte Chemie, 2007Wetter is better: The direct arylation of thiazoles on water is quicker, cleaner, and higher-yielding than arylation in organic solvents. The reaction works under mild conditions for an array of aryl iodides, producing 2,5-diaryl thiazoles in excellent yields.
Turner, Gemma L. +2 more
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The Thiazole Aldehyde Synthesis
Synthesis, 1998Aldehydes with diverse structural arrays are prepared by construction of carbon chains at C-2 of the thiazole ring and conversion of the heterocycle into the formyl group. Various methods are described that differ depending on the type of thiazole-based reagent employed in the initial carbon-carbon bond forming reaction leading to 2-substituted ...
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Imidazole, oxazole and thiazole alkaloids
Natural Product Reports, 2006AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
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Synthesis of Thiazoles from Metalated Thiazoles
2010P. A. Koutentis, H. A. Ioannidou
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