Results 101 to 110 of about 38,393 (221)
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aims To explore sex‐specific heterogeneity in the prognostic discrimination of inflammatory markers for mortality across different glycaemic states. Methods This prospective cohort study included 450 438 participants from the UK Biobank (median follow‐up: 15.3 years), stratified by sex and glycaemic status.
Yawen Zhang +5 more
wiley +1 more source
Frontiers in PharmacologyThe therapeutic targeting of peroxisome proliferator-activated receptor gamma (PPARγ) for type 2 diabetes (T2D) remains a double-edged sword: while thiazolidinediones are efficacious, their severe side effects necessitate the discovery of safer ...
Kalpana Panati +2 more
doaj +1 more source
Impact of hypoglycemia on patients with type 2 diabetes mellitus and their quality of life, work productivity, and medication adherence. [PDF]
, 2014 BackgroundThe purpose of this study was to determine the characteristics of adults with type 2 diabetes mellitus (T2DM) that correlate with greater risk of hypoglycemia and determine the impact of hypoglycemia on health-related quality of life, work ...
Annunziata, Kathy +4 more
core +3 more sources
Pleiotropic effects of thiazolidinediones
Expert Opinion on Pharmacotherapy, 2008 Insulin resistance and hyperglycemia characterize type 2 diabetes mellitus. Type 2 diabetes mellitus is usually accompanied by concomitant disorders, such as dyslipidemia, hypertension and atherosclerosis. Thiazolidinediones are antidiabetic drugs that increase insulin sensitivity by activating the peroxisome proliferator-activated receptor gamma ...
Rizos, C. V. +3 more
openaire +3 more sources
Association of GLP‐1 Receptor Agonists With Hepatic Decompensation in the All of Us Research Program
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aims To evaluate the association between glucagon‐like peptide‐1 receptor agonist (GLP‐1RA) initiation and the risk of hepatic decompensation compared with dipeptidyl peptidase 4 inhibitors (DPP4is) in a racially and ethnically diverse cohort of adults with Type 2 diabetes.
Inyoung Hwang, Yun Kim, Sang Won Lee
wiley +1 more source
Dementia Risk in Type 1 and 2 Diabetes: A Nationwide Population‐Based Comparison
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aims Diabetes is increasingly recognised as a major contributor to cognitive decline and dementia, but the risk varies by diabetes type and treatment intensity. We compared the risk of all‐cause dementia, Alzheimer's disease (AD) and vascular dementia (VaD) among individuals with and without diabetes.
Ji Eun Jun +3 more
wiley +1 more source
Neoplasia: An International Journal for Oncology Research, 2006 Peroxisome proliferator-activated receptor-δ (PPAR-δ) is a ligand-activated transcription factor. In addition to its canonical role in lipid, glucose metabolism, PPAR-δ controls cell proliferation, death, differentiation in several tissues.
Sara Vignati +9 more
doaj +1 more source
Reporting guidelines, review of methodological standards, and challenges toward harmonization in bone marrow adiposity research. Report of the Methodologies Working Group of the International Bone Marrow Adiposity Society [PDF]
, 2020 The interest in bone marrow adiposity (BMA) has increased over the last decade due to its association with, and potential role, in a range of diseases (osteoporosis, diabetes, anorexia, cancer) as well as treatments (corticosteroid, radiation ...
et al, +2 more
core +1 more source
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aim Waist‐to‐height ratio (WHtR) has been suggested as a superior marker of cardiometabolic risk compared to waist circumference (WC), but evidence in type 2 diabetes mellitus (T2DM) remains limited. Materials and Methods A population‐based cohort of 2 076 104 patients with T2DM who underwent the Korean national health checkup between 2015 and
Kye‐Yeung Park +7 more
wiley +1 more source