Effect of thermosonication on the UHPLC‐QTOF‐IMS‐based metabolomic profile of orange juice
Abstract Background This study investigated the impact of thermosonication on the metabolomic profile of orange juice to understand processing‐induced alterations in bioactive compounds and quality attributes. Results Moderate thermosonication at 45°C preserved structural siloxanes and certain amino acids, whereas higher temperatures between 60 and 75 ...
Deepti Kothari +4 more
wiley +1 more source
Comparative effects of second-line oral antidiabetic medications on atrial fibrillation risk in patients with type 2 diabetes: a nationwide retrospective cohort study. [PDF]
Heo GY +11 more
europepmc +1 more source
Type 2 Diabetes Mellitus: Molecular Pathogenesis and Therapeutic Interventions
This graphical summary illustrates the multiorgan therapeutic landscape for Type 2 diabetes mellitus (T2D), integrating molecular pathogenesis with modern treatment strategies. It depicts how current interventions, including SGLT2 inhibitors, GLP‐1 receptor agonists, and insulin secretagogues, target key organs—kidney, pancreas, gastrointestinal tract,
Shinuan Fei +9 more
wiley +1 more source
Comparative risk of the neurodegenerative outcomes between sodium-glucose co-transporter 2 (SGLT2) inhibitors and thiazolidinediones in type 2 diabetes: a multicentre cohort study using the Korean healthcare database (2014-2025). [PDF]
Park SJ +19 more
europepmc +1 more source
Central obesity and dyslipidaemia converge to impair insulin signalling and trigger chronic inflammation, oxidative stress, and mitochondrial dysfunction. This integrated metabolic disruption drives lipid imbalance, apoptosis, and persistent hyperglycaemia, ultimately accelerating the progression of type 2 diabetes and cardiovascular disease.
Muhammad Reva Aditya +11 more
wiley +1 more source
Antidiabetic drug and chronic respiratory disease in type 2 diabetes: a network meta-analysis and Mendelian randomization analysis. [PDF]
Patel I +7 more
europepmc +1 more source
ABSTRACT Objective Remote interventions leveraging team‐based care may ameliorate persistent gaps in obesity medication implementation, but prospective studies are lacking. In this paper, the design, enrollment, and implementation of a remote intervention for obesity medications are described.
Bryn Falahee +20 more
wiley +1 more source
Outcomes of oral antidiabetic drugs in metabolic dysfunction-associated steatotic liver disease: a nationwide target trial emulation study. [PDF]
Jang H +10 more
europepmc +1 more source
In this territory‐wide cohort study, improving glycemic control can be observed regardless of cirrhosis status. Oral antidiabetic medication was more often used in the non‐cirrhosis group, and insulin was preferred in patients with decompensated cirrhosis, who exhibited an increasing incidence of hypoglycemia over the years and need individualized ...
Mary Yue Wang +6 more
wiley +1 more source
Comparative Longitudinal Evaluation of Systemic Inflammatory Markers in Type 2 Diabetes Treated with Four Oral Antidiabetic Drug Classes. [PDF]
Yamak M +5 more
europepmc +1 more source

