Results 191 to 200 of about 24,637 (218)

Pharmacokinetic Interactions with Thiazolidinediones

Clinical Pharmacokinetics, 2007
Type 2 diabetes mellitus is a complex disease combining defects in insulin secretion and insulin action. New compounds called thiazolidinediones or glitazones have been developed for reducing insulin resistance. After the withdrawal of troglitazone because of liver toxicity, two compounds are currently used in clinical practice, rosiglitazone and ...
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The mode of action of thiazolidinediones

Diabetes/Metabolism Research and Reviews, 2002
The thiazolidinediones (TZDs) or 'glitazones' are a new class of oral antidiabetic drugs that improve metabolic control in patients with type 2 diabetes through the improvement of insulin sensitivity. TZDs exert their antidiabetic effects through a mechanism that involves activation of the gamma isoform of the peroxisome proliferator-activated receptor
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Information on thiazolidinediones

The Lancet, 2000
S M, Wolfe, P, Lurie, L D, Sasich, E, Barbehenn   +3 more
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Pharmacogenetics of Thiazolidinedione Therapy

Pharmacogenomics, 2007
The thiazolidinediones (TZDs) are peroxisome proliferator-activated receptor-gamma agonists and have glucose-lowering, insulin-sensitizing and anti-inflammatory effects. TZDs are approved for the treatment of Type 2 diabetes, and have been studied as a diabetes-prevention strategy.
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Hepatotoxicity of thiazolidinediones

Diabetes, Obesity and Metabolism, 2001
W L, Isley, J C, Oki
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Thiazolidinediones

Nihon rinsho. Japanese journal of clinical medicine, 2011
Tsukasa, Nakamura, Yoshihiko, Ueda
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Synthesis and Biological Activity of Novel Acridinylidene and Benzylidene thiazolidinediones

European Journal of Medicinal Chemistry, 2005
S L Galdino, I R Pitta
exaly  

Effect of Thiazolidinediones on Albuminuria and Proteinuria in Diabetes: A Meta-analysis

American Journal of Kidney Diseases, 2010
Pantelis Sarafidis, Panagiotis C Stafylas, Panagiotis I Georgianos   +2 more
exaly  

Synthesis and biological evaluation of novel pyrazolyl-2,4-thiazolidinediones as anti-inflammatory and neuroprotective agents

Bioorganic and Medicinal Chemistry, 2010
Amal M Youssef, Erika B Villanueva, Ibrahim M El-Ashmawy   +2 more
exaly  

The potential of antidiabetic thiazolidinediones for anticancer therapy

Expert Opinion on Investigational Drugs, 2006
Andrea Galli, Tommaso Mello, Elisabetta Ceni   +2 more
exaly